FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308954804> ?p ?o ?g. }

• W4308954804 endingPage "1133" @default.
• W4308954804 startingPage "1117" @default.
• W4308954804 abstract "Xenon-129 (129 Xe) gas-exchange MRI is a pulmonary-imaging technique that provides quantitative metrics for lung structure and function and is often compared to pulmonary-function tests. Unlike such tests, it does not normalize to predictive values based on demographic variables such as age. Many sites have alluded to an age dependence in gas-exchange metrics; however, a procedure for normalizing metrics has not yet been introduced.We model healthy reference values for 129 Xe gas-exchange MRI against age using generalized additive models for location, scale, and shape (GAMLSS). GAMLSS takes signal data from an aggregated heathy-reference cohort and fits a distribution with flexible median, variation, skewness, and kurtosis to predict age-dependent centiles. This approach mirrors methods by the Global Lung Function Initiative for modeling pulmonary-function test data and applies it to binning methods widely used by the 129 Xe MRI community to interpret and quantify gas-exchange data.Ventilation, membrane-uptake, red blood cell transfer, and red blood cell:membrane gas-exchange metrics were collected on 30 healthy subjects over an age range of 5 to 68 years. A GAMLSS model was fit against age and compared against widely used linear and generalized-linear binning 129 Xe MRI analysis schemes.All 4 gas-exchange metrics had significant skewness, and membrane-uptake had significant kurtosis compared to a normal distribution. Age has significant impact on distribution parameters. GAMLSS-binning produced narrower bins compared to the linear and generalized-linear binning schemes and distributed signal data closer to a normal distribution.The proposed proof-of-concept GAMLSS-binning approach can improve diagnostic accuracy of 129 Xe gas-exchange MRI by providing a means of modeling voxel distribution data against age." @default.
• W4308954804 created "2022-11-20" @default.
• W4308954804 creator A5011514885 @default.
• W4308954804 creator A5020592001 @default.
• W4308954804 creator A5029288113 @default.
• W4308954804 creator A5057850897 @default.
• W4308954804 creator A5058015755 @default.
• W4308954804 creator A5065013059 @default.
• W4308954804 date "2022-11-13" @default.
• W4308954804 modified "2023-10-15" @default.
• W4308954804 title "Childhood to adulthood: Accounting for age dependence in <scp>healthy‐reference</scp> distributions in <scp>¹²⁹Xe gas‐exchange MRI</scp>" @default.
• W4308954804 cites W1507444366 @default.
• W4308954804 cites W1512638735 @default.
• W4308954804 cites W1829161158 @default.
• W4308954804 cites W1899002956 @default.
• W4308954804 cites W1917018142 @default.
• W4308954804 cites W1974102437 @default.
• W4308954804 cites W1979427597 @default.
• W4308954804 cites W1985643930 @default.
• W4308954804 cites W1990420052 @default.
• W4308954804 cites W1993453452 @default.
• W4308954804 cites W1996604181 @default.
• W4308954804 cites W2000011103 @default.
• W4308954804 cites W2000198726 @default.
• W4308954804 cites W2006487405 @default.
• W4308954804 cites W2016918225 @default.
• W4308954804 cites W2018762529 @default.
• W4308954804 cites W2054344391 @default.
• W4308954804 cites W2069557359 @default.
• W4308954804 cites W2076760127 @default.
• W4308954804 cites W2099449365 @default.
• W4308954804 cites W2100236802 @default.
• W4308954804 cites W2103056943 @default.
• W4308954804 cites W2107026277 @default.
• W4308954804 cites W2114263671 @default.
• W4308954804 cites W2116627890 @default.
• W4308954804 cites W2117340355 @default.
• W4308954804 cites W2119160928 @default.
• W4308954804 cites W2136326182 @default.
• W4308954804 cites W2149707004 @default.
• W4308954804 cites W2154065358 @default.
• W4308954804 cites W2154394773 @default.
• W4308954804 cites W2155691361 @default.
• W4308954804 cites W2157355630 @default.
• W4308954804 cites W2162976407 @default.
• W4308954804 cites W2171024790 @default.
• W4308954804 cites W2277290778 @default.
• W4308954804 cites W2281213695 @default.
• W4308954804 cites W2394947526 @default.
• W4308954804 cites W2513285940 @default.
• W4308954804 cites W2604112991 @default.
• W4308954804 cites W2750789564 @default.
• W4308954804 cites W2752942070 @default.
• W4308954804 cites W2755145368 @default.
• W4308954804 cites W2884742303 @default.
• W4308954804 cites W2890919524 @default.
• W4308954804 cites W2898357610 @default.
• W4308954804 cites W2913822965 @default.
• W4308954804 cites W2937481901 @default.
• W4308954804 cites W2979309248 @default.
• W4308954804 cites W2991332808 @default.
• W4308954804 cites W3011013892 @default.
• W4308954804 cites W3091918949 @default.
• W4308954804 cites W3092628914 @default.
• W4308954804 cites W3097101884 @default.
• W4308954804 cites W3102894679 @default.
• W4308954804 cites W3109137990 @default.
• W4308954804 cites W3112717819 @default.
• W4308954804 cites W3135011014 @default.
• W4308954804 cites W3136914581 @default.
• W4308954804 cites W3157062036 @default.
• W4308954804 cites W3157623571 @default.
• W4308954804 cites W3165608290 @default.
• W4308954804 cites W3179277900 @default.
• W4308954804 cites W3185549342 @default.
• W4308954804 cites W3195131345 @default.
• W4308954804 cites W3197317142 @default.
• W4308954804 cites W3200725112 @default.
• W4308954804 cites W4214863976 @default.
• W4308954804 cites W4223541986 @default.
• W4308954804 cites W4237210482 @default.
• W4308954804 cites W4241468802 @default.
• W4308954804 cites W4299627282 @default.
• W4308954804 cites W4308954804 @default.
• W4308954804 cites W2766277706 @default.
• W4308954804 doi "https://doi.org/10.1002/mrm.29501" @default.
• W4308954804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36372970" @default.
• W4308954804 hasPublicationYear "2022" @default.
• W4308954804 type Work @default.
• W4308954804 citedByCount "4" @default.
• W4308954804 countsByYear W43089548042022 @default.
• W4308954804 countsByYear W43089548042023 @default.
• W4308954804 crossrefType "journal-article" @default.
• W4308954804 hasAuthorship W4308954804A5011514885 @default.
• W4308954804 hasAuthorship W4308954804A5020592001 @default.
• W4308954804 hasAuthorship W4308954804A5029288113 @default.
• W4308954804 hasAuthorship W4308954804A5057850897 @default.
• W4308954804 hasAuthorship W4308954804A5058015755 @default.

• next