Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308957033> ?p ?o ?g. }
- W4308957033 abstract "Abstract Dynamic regulation of nanoparticles in a controllable manner has great potential in various areas. Compared to the individual nanoparticles, the assembled nanoparticles exhibit superior properties and functions, which can be applied to achieve desirable performances. Here, a pH‐responsive i‐motif DNA‐mediated strategy to tailor the programmable behaviors of erbium‐based rare‐earth nanoparticles (ErNPs) decorated copper doped metal‐organic framework (CPM) nanohybrids (ECPM) under physiological conditions is reported. Within the acidic tumor microenvironment, the i‐motif DNA strands are able to form quadruplex structures, resulting in the assembly of nanohybrids and selective tumor accumulation, which further amplify the ErNPs downconversion emission (1550 nm) signal for imaging. Meanwhile, the ECPM matrix acts as a near‐infrared (NIR) photon‐activated reactive oxygen species (ROS) amplifier through the singlet oxygen generation of the matrix in combination with its ability of intracellular glutathione depletion upon irradiation. In short, this work displays a classical example of engineering of nanoparticles, which will manifest the importance of developing nanohybrids with structural programmability in biomedical applications." @default.
- W4308957033 created "2022-11-20" @default.
- W4308957033 creator A5001741146 @default.
- W4308957033 creator A5004219097 @default.
- W4308957033 creator A5005289701 @default.
- W4308957033 creator A5013272580 @default.
- W4308957033 creator A5015968273 @default.
- W4308957033 creator A5018249388 @default.
- W4308957033 creator A5032666798 @default.
- W4308957033 creator A5058418407 @default.
- W4308957033 creator A5060993342 @default.
- W4308957033 creator A5074655512 @default.
- W4308957033 creator A5077395012 @default.
- W4308957033 date "2022-11-14" @default.
- W4308957033 modified "2023-10-14" @default.
- W4308957033 title "Responsive Accumulation of Nanohybrids to Boost NIR‐Phototheranostics for Specific Tumor Imaging and Glutathione Depletion‐Enhanced Synergistic Therapy" @default.
- W4308957033 cites W1979321972 @default.
- W4308957033 cites W1998345142 @default.
- W4308957033 cites W2005496979 @default.
- W4308957033 cites W2015795331 @default.
- W4308957033 cites W2036263185 @default.
- W4308957033 cites W2039573122 @default.
- W4308957033 cites W2049716172 @default.
- W4308957033 cites W2058803970 @default.
- W4308957033 cites W2068050569 @default.
- W4308957033 cites W2101350424 @default.
- W4308957033 cites W2116272749 @default.
- W4308957033 cites W2117552063 @default.
- W4308957033 cites W2171083652 @default.
- W4308957033 cites W2184297178 @default.
- W4308957033 cites W2279490582 @default.
- W4308957033 cites W2508353289 @default.
- W4308957033 cites W2512441039 @default.
- W4308957033 cites W2559793130 @default.
- W4308957033 cites W2561923378 @default.
- W4308957033 cites W2586568190 @default.
- W4308957033 cites W2602077418 @default.
- W4308957033 cites W2610530035 @default.
- W4308957033 cites W2612058835 @default.
- W4308957033 cites W2613352698 @default.
- W4308957033 cites W2624317658 @default.
- W4308957033 cites W2738131416 @default.
- W4308957033 cites W2740337666 @default.
- W4308957033 cites W2791342926 @default.
- W4308957033 cites W2793503277 @default.
- W4308957033 cites W2796348401 @default.
- W4308957033 cites W2807142617 @default.
- W4308957033 cites W2860296076 @default.
- W4308957033 cites W2883266145 @default.
- W4308957033 cites W2883358359 @default.
- W4308957033 cites W2884689002 @default.
- W4308957033 cites W2889882288 @default.
- W4308957033 cites W2894033777 @default.
- W4308957033 cites W2896381621 @default.
- W4308957033 cites W2901577109 @default.
- W4308957033 cites W2905485852 @default.
- W4308957033 cites W2907041641 @default.
- W4308957033 cites W2907510538 @default.
- W4308957033 cites W2948231961 @default.
- W4308957033 cites W2970761159 @default.
- W4308957033 cites W2975715205 @default.
- W4308957033 cites W3012039292 @default.
- W4308957033 cites W3132440774 @default.
- W4308957033 cites W3132531394 @default.
- W4308957033 cites W3133397430 @default.
- W4308957033 cites W3171129376 @default.
- W4308957033 cites W4210726819 @default.
- W4308957033 cites W4308957033 @default.
- W4308957033 cites W58295951 @default.
- W4308957033 doi "https://doi.org/10.1002/advs.202205208" @default.
- W4308957033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36373690" @default.
- W4308957033 hasPublicationYear "2022" @default.
- W4308957033 type Work @default.
- W4308957033 citedByCount "3" @default.
- W4308957033 countsByYear W43089570332022 @default.
- W4308957033 countsByYear W43089570332023 @default.
- W4308957033 crossrefType "journal-article" @default.
- W4308957033 hasAuthorship W4308957033A5001741146 @default.
- W4308957033 hasAuthorship W4308957033A5004219097 @default.
- W4308957033 hasAuthorship W4308957033A5005289701 @default.
- W4308957033 hasAuthorship W4308957033A5013272580 @default.
- W4308957033 hasAuthorship W4308957033A5015968273 @default.
- W4308957033 hasAuthorship W4308957033A5018249388 @default.
- W4308957033 hasAuthorship W4308957033A5032666798 @default.
- W4308957033 hasAuthorship W4308957033A5058418407 @default.
- W4308957033 hasAuthorship W4308957033A5060993342 @default.
- W4308957033 hasAuthorship W4308957033A5074655512 @default.
- W4308957033 hasAuthorship W4308957033A5077395012 @default.
- W4308957033 hasBestOaLocation W43089570331 @default.
- W4308957033 hasConcept C12554922 @default.
- W4308957033 hasConcept C155672457 @default.
- W4308957033 hasConcept C171250308 @default.
- W4308957033 hasConcept C178790620 @default.
- W4308957033 hasConcept C181199279 @default.
- W4308957033 hasConcept C185592680 @default.
- W4308957033 hasConcept C192562407 @default.
- W4308957033 hasConcept C2776107976 @default.
- W4308957033 hasConcept C2777516457 @default.
- W4308957033 hasConcept C3020616263 @default.
- W4308957033 hasConcept C48349386 @default.