FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308974759> ?p ?o ?g. }

• W4308974759 abstract "Abstract Background Hypobaric hypoxia is common at high altitudes. Whether this exacerbates hypoxia during procedural sedation and whether hypoxia can be alleviated by the use of supraglottic jet oxygenation and ventilation (SJOV) are unknown. This study aimed to compare the incidence of hypoxia during gastrointestinal endoscopy under deep sedation at high altitudes with oxygen supply techniques using either a nasal cannula or SJOV. Methods This study was conducted from April 2022 to July 2022 in a tertiary hospital located 3650 m above sea level. Adult patients scheduled for routine gastrointestinal endoscopy under sedation were enrolled and randomized 1:1 to receive SJOV or a nasal cannula during sedation. Moderate hypoxia was the primary outcome, defined as an SPO 2 of 75–89% for < 60 s. The secondary outcomes were respiratory-, cardiovascular-, and SJOV-related complications. The influence of characteristics regarding acclimatization to high altitudes (Tibetan ethnic group and erythrocytosis) on the occurrence of hypoxia was analyzed. Results None of the patients were lost to follow-up. A total of 72 patients were included in the analysis (36 patients in each group). There were 20 (27.8%) patients who experienced moderate hypoxia events. Significantly fewer hypoxic events occurred in the SJOV group than in the nasal cannula group [3 (8.3%) vs. 17 (47.2%), absolute risk difference (95% CI): − 38.9 (− 57.5, − 20.2) %, risk ratio (RR, 95% CI): 0.18 (0.06, 0.55), P < 0.001]. Significantly fewer patients in the SJOV group experienced mild hypoxia (P < 0.001) and severe hypoxia ( P = 0.002). No serious adverse events occurred in either of the groups. The Tibetan ethnic group ( P = 0.086) and erythrocytosis ( P = 0.287) were not associated with the occurrence of hypoxia events. Conclusions The incidence of hypoxia was lower with SJOV than with nasal cannula in patients undergoing gastrointestinal endoscopy under deep sedation at high altitudes. The Tibetan ethnic group and erythrocytosis did not influence the occurrence of hypoxia. Trial registration This study was registered at ClinicalTrials.gov (NCT05304923) before enrollment by Dr. Yi Feng on 31/03/2022." @default.
• W4308974759 created "2022-11-20" @default.
• W4308974759 creator A5022201218 @default.
• W4308974759 creator A5031961027 @default.
• W4308974759 creator A5038823041 @default.
• W4308974759 creator A5064842058 @default.
• W4308974759 creator A5065988302 @default.
• W4308974759 creator A5090526256 @default.
• W4308974759 date "2022-11-14" @default.
• W4308974759 modified "2023-10-09" @default.
• W4308974759 title "Supraglottic jet oxygenation and ventilation decreased hypoxemia during gastrointestinal endoscopy under deep sedation at high altitudes: a randomized clinical trial" @default.
• W4308974759 cites W123609371 @default.
• W4308974759 cites W1991765190 @default.
• W4308974759 cites W1995920079 @default.
• W4308974759 cites W2002913576 @default.
• W4308974759 cites W2025661585 @default.
• W4308974759 cites W2060483697 @default.
• W4308974759 cites W2061051580 @default.
• W4308974759 cites W2553873063 @default.
• W4308974759 cites W2584358852 @default.
• W4308974759 cites W2725194017 @default.
• W4308974759 cites W2781526186 @default.
• W4308974759 cites W2791851888 @default.
• W4308974759 cites W2799505092 @default.
• W4308974759 cites W2891122122 @default.
• W4308974759 cites W2940113088 @default.
• W4308974759 cites W2944592476 @default.
• W4308974759 cites W2960127425 @default.
• W4308974759 cites W3025895727 @default.
• W4308974759 cites W3094300534 @default.
• W4308974759 cites W3097745254 @default.
• W4308974759 cites W3120384989 @default.
• W4308974759 cites W3133612160 @default.
• W4308974759 cites W3181106149 @default.
• W4308974759 cites W3194477300 @default.
• W4308974759 cites W4225162106 @default.
• W4308974759 cites W4226087653 @default.
• W4308974759 cites W4285741444 @default.
• W4308974759 doi "https://doi.org/10.1186/s12871-022-01902-3" @default.
• W4308974759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36376852" @default.
• W4308974759 hasPublicationYear "2022" @default.
• W4308974759 type Work @default.
• W4308974759 citedByCount "0" @default.
• W4308974759 crossrefType "journal-article" @default.
• W4308974759 hasAuthorship W4308974759A5022201218 @default.
• W4308974759 hasAuthorship W4308974759A5031961027 @default.
• W4308974759 hasAuthorship W4308974759A5038823041 @default.
• W4308974759 hasAuthorship W4308974759A5064842058 @default.
• W4308974759 hasAuthorship W4308974759A5065988302 @default.
• W4308974759 hasAuthorship W4308974759A5090526256 @default.
• W4308974759 hasBestOaLocation W43089747591 @default.
• W4308974759 hasConcept C141071460 @default.
• W4308974759 hasConcept C168563851 @default.
• W4308974759 hasConcept C178790620 @default.
• W4308974759 hasConcept C185592680 @default.
• W4308974759 hasConcept C2776779939 @default.
• W4308974759 hasConcept C2776814716 @default.
• W4308974759 hasConcept C2778074680 @default.
• W4308974759 hasConcept C2780334268 @default.
• W4308974759 hasConcept C2780630273 @default.
• W4308974759 hasConcept C42219234 @default.
• W4308974759 hasConcept C540031477 @default.
• W4308974759 hasConcept C70289976 @default.
• W4308974759 hasConcept C71924100 @default.
• W4308974759 hasConcept C7836513 @default.
• W4308974759 hasConceptScore W4308974759C141071460 @default.
• W4308974759 hasConceptScore W4308974759C168563851 @default.
• W4308974759 hasConceptScore W4308974759C178790620 @default.
• W4308974759 hasConceptScore W4308974759C185592680 @default.
• W4308974759 hasConceptScore W4308974759C2776779939 @default.
• W4308974759 hasConceptScore W4308974759C2776814716 @default.
• W4308974759 hasConceptScore W4308974759C2778074680 @default.
• W4308974759 hasConceptScore W4308974759C2780334268 @default.
• W4308974759 hasConceptScore W4308974759C2780630273 @default.
• W4308974759 hasConceptScore W4308974759C42219234 @default.
• W4308974759 hasConceptScore W4308974759C540031477 @default.
• W4308974759 hasConceptScore W4308974759C70289976 @default.
• W4308974759 hasConceptScore W4308974759C71924100 @default.
• W4308974759 hasConceptScore W4308974759C7836513 @default.
• W4308974759 hasIssue "1" @default.
• W4308974759 hasLocation W43089747591 @default.
• W4308974759 hasLocation W43089747592 @default.
• W4308974759 hasLocation W43089747593 @default.
• W4308974759 hasLocation W43089747594 @default.
• W4308974759 hasOpenAccess W4308974759 @default.
• W4308974759 hasPrimaryLocation W43089747591 @default.
• W4308974759 hasRelatedWork W164522067 @default.
• W4308974759 hasRelatedWork W2087393027 @default.
• W4308974759 hasRelatedWork W2570164355 @default.
• W4308974759 hasRelatedWork W2766335932 @default.
• W4308974759 hasRelatedWork W2780182720 @default.
• W4308974759 hasRelatedWork W2998277134 @default.
• W4308974759 hasRelatedWork W3014635033 @default.
• W4308974759 hasRelatedWork W3030521954 @default.
• W4308974759 hasRelatedWork W3147638419 @default.
• W4308974759 hasRelatedWork W3162678242 @default.
• W4308974759 hasVolume "22" @default.
• W4308974759 isParatext "false" @default.
• W4308974759 isRetracted "false" @default.
• W4308974759 workType "article" @default.