Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308979207> ?p ?o ?g. }
- W4308979207 endingPage "1319" @default.
- W4308979207 startingPage "1308" @default.
- W4308979207 abstract "In this study, the immunity-enhancing effect of ginger polysaccharides UGP1 and UGP2 on CTX-induced immunosuppressed mice was evaluated. The results showed that ginger polysaccharide could effectively alleviate the symptoms of weight loss and dietary intake reduction induced by CTX, increase fecal water content, reduce fecal pH, and protect immune organs of immunosuppressed mice. In addition, ginger polysaccharides also stimulated the secretion of cytokines IL-2, IL-4, TNF-α and immunoglobulin Ig-G in the serum of mice, increased the expression of Occludin and Claudin-1, and restored the level of short-chain fatty acids in the intestine to improve immune deficiency. Furthermore, ginger polysaccharides significantly reduced the relative abundance ratio of the Firmicutes and Bacteroidetes in mice and increased the relative abundance of Verrucomicrobia and Bacteroidetes at the phylum level. At the family level, ginger polysaccharides increased the relative abundance of beneficial bacteria such as Muribaculaceae, Bacteroidaceae and Lactobacillaceae, and decreased the relative abundance of harmful bacteria such as Rikenellaceae and Lachnospiraceae. Spearman correlation analysis indicated that ginger polysaccharides could enhance intestinal immunity by modulating gut microbiota associated with immune function. These results indicated that ginger polysaccharides have the potential to be a functional food ingredients or a natural medicine for the treatment of intestinal barrier injury." @default.
- W4308979207 created "2022-11-20" @default.
- W4308979207 creator A5016117536 @default.
- W4308979207 creator A5060943980 @default.
- W4308979207 creator A5065189030 @default.
- W4308979207 creator A5066286401 @default.
- W4308979207 creator A5075877965 @default.
- W4308979207 creator A5081135973 @default.
- W4308979207 date "2022-12-01" @default.
- W4308979207 modified "2023-10-15" @default.
- W4308979207 title "Ginger polysaccharides enhance intestinal immunity by modulating gut microbiota in cyclophosphamide-induced immunosuppressed mice" @default.
- W4308979207 cites W1919048856 @default.
- W4308979207 cites W1970841758 @default.
- W4308979207 cites W1977807397 @default.
- W4308979207 cites W1983283128 @default.
- W4308979207 cites W1992152055 @default.
- W4308979207 cites W2014444288 @default.
- W4308979207 cites W2018745802 @default.
- W4308979207 cites W2020597244 @default.
- W4308979207 cites W2037793614 @default.
- W4308979207 cites W2045601755 @default.
- W4308979207 cites W2048286567 @default.
- W4308979207 cites W2052285453 @default.
- W4308979207 cites W2078224825 @default.
- W4308979207 cites W2089971562 @default.
- W4308979207 cites W2091347173 @default.
- W4308979207 cites W2134296999 @default.
- W4308979207 cites W2142537875 @default.
- W4308979207 cites W2148067809 @default.
- W4308979207 cites W2175425219 @default.
- W4308979207 cites W2208452542 @default.
- W4308979207 cites W2737938730 @default.
- W4308979207 cites W2742196080 @default.
- W4308979207 cites W2766907509 @default.
- W4308979207 cites W2788996218 @default.
- W4308979207 cites W2792085932 @default.
- W4308979207 cites W2803019427 @default.
- W4308979207 cites W2886690355 @default.
- W4308979207 cites W2898469163 @default.
- W4308979207 cites W2899994367 @default.
- W4308979207 cites W2901972393 @default.
- W4308979207 cites W2911267231 @default.
- W4308979207 cites W2913164636 @default.
- W4308979207 cites W2942824734 @default.
- W4308979207 cites W2943709813 @default.
- W4308979207 cites W2944364661 @default.
- W4308979207 cites W2948064083 @default.
- W4308979207 cites W2949616874 @default.
- W4308979207 cites W2955098547 @default.
- W4308979207 cites W2966151838 @default.
- W4308979207 cites W2969258908 @default.
- W4308979207 cites W2981759133 @default.
- W4308979207 cites W2988049488 @default.
- W4308979207 cites W2993542661 @default.
- W4308979207 cites W3011607393 @default.
- W4308979207 cites W3018966941 @default.
- W4308979207 cites W3019767571 @default.
- W4308979207 cites W3104106142 @default.
- W4308979207 cites W3158866109 @default.
- W4308979207 cites W4210686042 @default.
- W4308979207 cites W4295197026 @default.
- W4308979207 doi "https://doi.org/10.1016/j.ijbiomac.2022.11.104" @default.
- W4308979207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36395935" @default.
- W4308979207 hasPublicationYear "2022" @default.
- W4308979207 type Work @default.
- W4308979207 citedByCount "8" @default.
- W4308979207 countsByYear W43089792072023 @default.
- W4308979207 crossrefType "journal-article" @default.
- W4308979207 hasAuthorship W4308979207A5016117536 @default.
- W4308979207 hasAuthorship W4308979207A5060943980 @default.
- W4308979207 hasAuthorship W4308979207A5065189030 @default.
- W4308979207 hasAuthorship W4308979207A5066286401 @default.
- W4308979207 hasAuthorship W4308979207A5075877965 @default.
- W4308979207 hasAuthorship W4308979207A5081135973 @default.
- W4308979207 hasConcept C100817775 @default.
- W4308979207 hasConcept C126322002 @default.
- W4308979207 hasConcept C203014093 @default.
- W4308979207 hasConcept C2777385719 @default.
- W4308979207 hasConcept C2777695942 @default.
- W4308979207 hasConcept C2779341262 @default.
- W4308979207 hasConcept C2779704485 @default.
- W4308979207 hasConcept C3019368612 @default.
- W4308979207 hasConcept C42062724 @default.
- W4308979207 hasConcept C523546767 @default.
- W4308979207 hasConcept C539455810 @default.
- W4308979207 hasConcept C54355233 @default.
- W4308979207 hasConcept C55493867 @default.
- W4308979207 hasConcept C71924100 @default.
- W4308979207 hasConcept C86803240 @default.
- W4308979207 hasConcept C8891405 @default.
- W4308979207 hasConcept C89423630 @default.
- W4308979207 hasConceptScore W4308979207C100817775 @default.
- W4308979207 hasConceptScore W4308979207C126322002 @default.
- W4308979207 hasConceptScore W4308979207C203014093 @default.
- W4308979207 hasConceptScore W4308979207C2777385719 @default.
- W4308979207 hasConceptScore W4308979207C2777695942 @default.
- W4308979207 hasConceptScore W4308979207C2779341262 @default.
- W4308979207 hasConceptScore W4308979207C2779704485 @default.