FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309002247> ?p ?o ?g. }

• W4309002247 endingPage "2895" @default.
• W4309002247 startingPage "2895" @default.
• W4309002247 abstract "Local ablative treatment is another option for improving outcomes and has been evaluated for locally advanced pancreatic cancer. We previously suggested endoscopic ultrasound (EUS)-guided interstitial laser ablation using a cylindrical laser diffuser (CILA) might be a feasible therapeutic option based on experiments performed on pancreatic cancer cell lines and porcine model with a short follow-up (3 days). The aim of this study was to investigate the safety of EUS-CILA performed using optimal settings in porcine pancreas with a long-term follow-up (2 weeks).EUS-CILA (laser energy of 450 J; 5 W for 90 s) was applied to normal pancreatic tissue in porcine (n = 5) under EUS guidance. Animals were observed clinically for 2 weeks after EUS-CILA to evaluate complications. Computed tomography and laboratory tests were carried out to evaluate safety. Two weeks after EUS-CILA, all pigs were sacrificed, and histopathological safety and efficacy evaluations were conducted.EUS-CILA was technically successful in all five cases. No major complications occurred during the follow-up period. Body weight of porcine did not change during the study period without any significant change in feed intake. Animals remained in excellent condition throughout the experimental period, and laboratory tests and computed tomography (CT) scans provided no evidence of a major complication. Histopathological evaluation showed complete ablation in the ablated area with clear delineation of surrounding normal pancreatic tissue. Mean ablated volume was 55.5 mm2 × 29.0 mm and mean ablated areas in the pancreatic sections of the five pigs were not significantly different (p = 0.368).In conclusion, our experimental study suggests that EUS-CILA is safe and has the potential to be an effective local treatment modality. No major morbidity or mortality occurred during the study period. Further evaluations are warranted before clinical application." @default.
• W4309002247 created "2022-11-20" @default.
• W4309002247 creator A5009309147 @default.
• W4309002247 creator A5012280116 @default.
• W4309002247 creator A5027561122 @default.
• W4309002247 creator A5031651983 @default.
• W4309002247 creator A5056976307 @default.
• W4309002247 creator A5059024287 @default.
• W4309002247 creator A5071827703 @default.
• W4309002247 creator A5076065046 @default.
• W4309002247 date "2022-11-11" @default.
• W4309002247 modified "2023-10-05" @default.
• W4309002247 title "Endoscopic Ultrasound-Guided Pancreatic Interstitial Laser Ablation Using a Cylindrical Laser Diffuser: A Long-Term Follow-Up Study" @default.
• W4309002247 cites W1963218025 @default.
• W4309002247 cites W2007994465 @default.
• W4309002247 cites W2011379556 @default.
• W4309002247 cites W2031079883 @default.
• W4309002247 cites W2048754796 @default.
• W4309002247 cites W2059662752 @default.
• W4309002247 cites W2108187778 @default.
• W4309002247 cites W2139547545 @default.
• W4309002247 cites W2159019210 @default.
• W4309002247 cites W2332844714 @default.
• W4309002247 cites W2514008771 @default.
• W4309002247 cites W2626092077 @default.
• W4309002247 cites W2743810706 @default.
• W4309002247 cites W2751201334 @default.
• W4309002247 cites W2770300664 @default.
• W4309002247 cites W2787763426 @default.
• W4309002247 cites W2807967418 @default.
• W4309002247 cites W2948066892 @default.
• W4309002247 cites W3022250631 @default.
• W4309002247 cites W3094033738 @default.
• W4309002247 cites W3128646645 @default.
• W4309002247 cites W3130863604 @default.
• W4309002247 cites W3171756474 @default.
• W4309002247 cites W3198418259 @default.
• W4309002247 cites W4213102285 @default.
• W4309002247 cites W4225314490 @default.
• W4309002247 doi "https://doi.org/10.3390/biomedicines10112895" @default.
• W4309002247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36428465" @default.
• W4309002247 hasPublicationYear "2022" @default.
• W4309002247 type Work @default.
• W4309002247 citedByCount "1" @default.
• W4309002247 countsByYear W43090022472023 @default.
• W4309002247 crossrefType "journal-article" @default.
• W4309002247 hasAuthorship W4309002247A5009309147 @default.
• W4309002247 hasAuthorship W4309002247A5012280116 @default.
• W4309002247 hasAuthorship W4309002247A5027561122 @default.
• W4309002247 hasAuthorship W4309002247A5031651983 @default.
• W4309002247 hasAuthorship W4309002247A5056976307 @default.
• W4309002247 hasAuthorship W4309002247A5059024287 @default.
• W4309002247 hasAuthorship W4309002247A5071827703 @default.
• W4309002247 hasAuthorship W4309002247A5076065046 @default.
• W4309002247 hasBestOaLocation W43090022471 @default.
• W4309002247 hasConcept C121608353 @default.
• W4309002247 hasConcept C126322002 @default.
• W4309002247 hasConcept C126838900 @default.
• W4309002247 hasConcept C143753070 @default.
• W4309002247 hasConcept C2778764654 @default.
• W4309002247 hasConcept C2778902805 @default.
• W4309002247 hasConcept C2780210213 @default.
• W4309002247 hasConcept C2780390042 @default.
• W4309002247 hasConcept C2989005 @default.
• W4309002247 hasConcept C71924100 @default.
• W4309002247 hasConceptScore W4309002247C121608353 @default.
• W4309002247 hasConceptScore W4309002247C126322002 @default.
• W4309002247 hasConceptScore W4309002247C126838900 @default.
• W4309002247 hasConceptScore W4309002247C143753070 @default.
• W4309002247 hasConceptScore W4309002247C2778764654 @default.
• W4309002247 hasConceptScore W4309002247C2778902805 @default.
• W4309002247 hasConceptScore W4309002247C2780210213 @default.
• W4309002247 hasConceptScore W4309002247C2780390042 @default.
• W4309002247 hasConceptScore W4309002247C2989005 @default.
• W4309002247 hasConceptScore W4309002247C71924100 @default.
• W4309002247 hasIssue "11" @default.
• W4309002247 hasLocation W43090022471 @default.
• W4309002247 hasLocation W43090022472 @default.
• W4309002247 hasLocation W43090022473 @default.
• W4309002247 hasLocation W43090022474 @default.
• W4309002247 hasOpenAccess W4309002247 @default.
• W4309002247 hasPrimaryLocation W43090022471 @default.
• W4309002247 hasRelatedWork W1936092177 @default.
• W4309002247 hasRelatedWork W2053545673 @default.
• W4309002247 hasRelatedWork W2082612687 @default.
• W4309002247 hasRelatedWork W2108137221 @default.
• W4309002247 hasRelatedWork W2282618560 @default.
• W4309002247 hasRelatedWork W2948094693 @default.
• W4309002247 hasRelatedWork W2963585294 @default.
• W4309002247 hasRelatedWork W2965490941 @default.
• W4309002247 hasRelatedWork W4386268453 @default.
• W4309002247 hasRelatedWork W47875464 @default.
• W4309002247 hasVolume "10" @default.
• W4309002247 isParatext "false" @default.
• W4309002247 isRetracted "false" @default.
• W4309002247 workType "article" @default.