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- W4309047069 abstract "Objective To evaluate latency and duration of a brachial plexus block technique in eastern box turtles performed with 2% lidocaine at three dose rates. Study design Prospective, randomized, blinded crossover study. Animals Adult eastern box turtles, two for drug dose evaluation and a group of six (three male, three female) weighing 432 ± 40 g (mean ± standard deviation) for the main study. Methods Animals were randomly assigned to four brachial plexus blocks with lidocaine at 5, 10 and 20 mg kg–1 or 0.9% saline (treatments LID5, LID10, LID20 and CON, respectively), separated by 1 week. Treatment side was randomized and blocks were performed unilaterally. Baseline observations of mentation, heart rate (HR), respiratory rate (fR), skin temperature and limb response to manipulation or toe pinch were evaluated. Assessments were made every 10 minutes until 1 hour of normal sensory and motor function to the treated thoracic limb, or for a total of 2 hours if no block was evident. Results Motor and sensory blockade was achieved in treatments LID10 and LID20 in one turtle, with a latency of 10 minutes and duration of 50 minutes for both doses. Raising of the ipsilateral lower palpebra occurred with both blocks. Turtles administered lidocaine experienced higher HR compared with CON, and HR decreased over time for all individuals. Mentation and fR were not changed with any lidocaine dose. Conclusions The technique was unreliable in producing brachial plexus motor and sensory blockade at the lidocaine doses evaluated in this study. HR was higher in lidocaine-administered turtles but remained within normal limits for the species. No change in mentation or fR was observed among treatments. Clinical relevance General anesthesia with systemic analgesia is recommended for surgical procedures involving the chelonian thoracic limb. Further studies are needed to optimize a brachial plexus block in this species." @default.
- W4309047069 created "2022-11-21" @default.
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- W4309047069 date "2023-01-01" @default.
- W4309047069 modified "2023-09-25" @default.
- W4309047069 title "Evaluation of lidocaine for brachial plexus blockade in eastern box turtles (Terrapene carolina carolina)" @default.
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- W4309047069 doi "https://doi.org/10.1016/j.vaa.2022.11.003" @default.
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