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• W4309073119 abstract "Introduction. New onset of diabetes mellitus was noted as the commonest comorbidity in the COVID-19 pandemic, which contributed to a worse prognosis. Existing evidence showed that new-onset diabetes is associated with increased mortality compared to nondiabetic and known diabetic patients in the COVID-19 era. SARS-CoV-2 virus can worsen existing diabetes; at the same time, it can trigger new-onset diabetes that eventually worsens patient outcomes. Thus, this study is aimed at determining the prevalence and factors associated with new onset of diabetes mellitus among COVID-19 patients. Methods. Institution-based retrospective cross-sectional study design was conducted by reviewing 244 patient’s records in the Addis Ababa COVID-19 care center. Descriptive statistics and binary logistic regression were used. During bivariate analysis, variables with <math xmlns=http://www.w3.org/1998/Math/MathML id=M1> <mi>p</mi> <mo>≤</mo> <mn>0.25</mn> </math> were transferred into multivariate analysis. Adjusted odds ratios to determine the strength and presence of the association with a 95% confidence interval and <math xmlns=http://www.w3.org/1998/Math/MathML id=M2> <mi>p</mi> </math> value ≤ 0.05 were considered, respectively. Results. The mean age of the study participants was 53.2 years with ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M3> <mtext>SD</mtext> <mo>=</mo> <mn>13.35</mn> </math> ). The study findings showed that 31.1% (CI: 25.4-37.4) of COVID-19 patients had new onset of diabetes mellitus; of those, 11.8% had type 1 and 88.2% had type 2 diabetes. Being male ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M4> <mtext>aOR</mtext> <mo>=</mo> <mn>2.9</mn> </math> ; 95% CI: 1.2, 7.1), family history of hypertension ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M5> <mtext>aOR</mtext> <mo>=</mo> <mn>3.7</mn> </math> ; 95% CI: 1.3, 10.5), obesity ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M6> <mtext>aOR</mtext> <mo>=</mo> <mn>3.1</mn> </math> ; 95% CI: 1.01, 8.9), having pulmonary embolism ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M7> <mtext>aOR</mtext> <mo>=</mo> <mn>0.2</mn> </math> ; 95% CI: 0.06, 0.04), and hyperkalemia ( <math xmlns=http://www.w3.org/1998/Math/MathML id=M8> <mtext>aOR</mtext> <mo>=</mo> <mn>9.3</mn> </math> ; 95% CI: 1.8, 47.3) showed statistically significant association with new onset of diabetes mellitus. Conclusion. A significant proportion of COVID-19 patients had been diagnosed with new onset of diabetes mellitus, and new-onset type 2 diabetes mellitus is the most common diabetes mellitus type. Being male, obesity, having a pulmonary embolism, family history of hypertension, and hyperkalemia were independently associated with new onset of diabetes mellitus among COVID-19 patients. Therefore, focused interventions need to be strengthened towards the identified factors." @default.
• W4309073119 created "2022-11-21" @default.
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• W4309073119 date "2022-11-12" @default.
• W4309073119 modified "2023-10-06" @default.
• W4309073119 title "New Onset of Diabetes Mellitus and Associated Factors among COVID-19 Patients in COVID-19 Care Centers, Addis Ababa, Ethiopia 2022" @default.
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• W4309073119 doi "https://doi.org/10.1155/2022/9652940" @default.
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