Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309185737> ?p ?o ?g. }
- W4309185737 abstract "Echocardiographic deformation-based ratios and novel multi-parametric scores have been suggested to discriminate transthyretin cardiac amyloidosis (ATTR-CM) from other causes of increased left ventricular wall thickness among patients referred for ATTR-CM evaluation. Their relative predictive accuracy has not been well studied. We sought to (1) identify echocardiographic parameters predictive of ATTR-CM and (2) compare the diagnostic accuracy of these parameters in patients with suspected ATTR-CM referred for technetium-99m-pyrophosphate scintigraphy.Echocardiograms from 598 patients referred to 3 major amyloidosis centers for technetium-99m-pyrophosphate to detect ATTR-CM were analyzed, including longitudinal strain (LS) analysis. Deformation ratios (septal apex to base ratio, relative apical sparing, ejection fraction to global LS), a multi-center European increased wall thickness score, and Mayo Clinic derived ATTR score (transthyretin cardiac amyloidosis score) were calculated. A logistic regression model was used to identify the parameters that best associated with a diagnosis of ATTR-CM. Comparison of the diagnostic capacity of the parameters was performed by receiver operating characteristic curves and the area under the curve (AUC).Over half of the subjects (54.2%) were diagnosed with ATTR-CM (78% were men, median age of 76 years). Age, inferolateral wall thickness, and basal LS were the strongest predictors of ATTR-CM, AUC of 0.87 (95% CI: 0.83, 0.90), superior to the increased wall thickness score AUC of 0.78 (95% CI: 0.73, 0.83; P=0.004). An inferolateral wall thickness of ≥14 mm (AUC: 0.73) was as accurate as the published cut-offs for transthyretin cardiac amyloidosis score and septal apex to base (AUC: 0.72 and 0.69, P=0.8 and P=0.1, respectively), and was superior to ejection fraction to global LS and relative apical sparing (AUC: 0.64 and 0.53, P<0.001, respectively). A cut-off of ≥-8% for average basal LS (AUC: 0.76, CI: 0.72-0.79) had a similar area under the curve to transthyretin cardiac amyloidosis score (TCAS) (P=0.2); outperforming the other indices (P<0.01).Inferolateral wall thickness and average basal LS performed as well as or better than more complex echo ratios and multiparametric scores to predict ATTR-CM." @default.
- W4309185737 created "2022-11-24" @default.
- W4309185737 creator A5005111256 @default.
- W4309185737 creator A5012664356 @default.
- W4309185737 creator A5038638827 @default.
- W4309185737 creator A5038946983 @default.
- W4309185737 creator A5044226573 @default.
- W4309185737 creator A5044435162 @default.
- W4309185737 creator A5045641510 @default.
- W4309185737 creator A5048185686 @default.
- W4309185737 creator A5059417970 @default.
- W4309185737 creator A5059866539 @default.
- W4309185737 creator A5064126602 @default.
- W4309185737 creator A5066274184 @default.
- W4309185737 creator A5071439155 @default.
- W4309185737 creator A5080799305 @default.
- W4309185737 creator A5089174509 @default.
- W4309185737 creator A5089456277 @default.
- W4309185737 date "2022-11-01" @default.
- W4309185737 modified "2023-10-16" @default.
- W4309185737 title "Optimal Echocardiographic Parameters to Improve the Diagnostic Yield of Tc-99m-Bone Avid Tracer Cardiac Scintigraphy for Transthyretin Cardiac Amyloidosis" @default.
- W4309185737 cites W2006617902 @default.
- W4309185737 cites W2097360283 @default.
- W4309185737 cites W2124624517 @default.
- W4309185737 cites W2132750428 @default.
- W4309185737 cites W2165312755 @default.
- W4309185737 cites W2337532627 @default.
- W4309185737 cites W2513537837 @default.
- W4309185737 cites W2774552946 @default.
- W4309185737 cites W2802991944 @default.
- W4309185737 cites W2885181221 @default.
- W4309185737 cites W2921617821 @default.
- W4309185737 cites W2968722358 @default.
- W4309185737 cites W2991462688 @default.
- W4309185737 cites W2995871188 @default.
- W4309185737 cites W3128347056 @default.
- W4309185737 cites W3197703209 @default.
- W4309185737 cites W4294541781 @default.
- W4309185737 cites W4294921091 @default.
- W4309185737 cites W55104719 @default.
- W4309185737 doi "https://doi.org/10.1161/circimaging.122.014645" @default.
- W4309185737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36378779" @default.
- W4309185737 hasPublicationYear "2022" @default.
- W4309185737 type Work @default.
- W4309185737 citedByCount "3" @default.
- W4309185737 countsByYear W43091857372023 @default.
- W4309185737 crossrefType "journal-article" @default.
- W4309185737 hasAuthorship W4309185737A5005111256 @default.
- W4309185737 hasAuthorship W4309185737A5012664356 @default.
- W4309185737 hasAuthorship W4309185737A5038638827 @default.
- W4309185737 hasAuthorship W4309185737A5038946983 @default.
- W4309185737 hasAuthorship W4309185737A5044226573 @default.
- W4309185737 hasAuthorship W4309185737A5044435162 @default.
- W4309185737 hasAuthorship W4309185737A5045641510 @default.
- W4309185737 hasAuthorship W4309185737A5048185686 @default.
- W4309185737 hasAuthorship W4309185737A5059417970 @default.
- W4309185737 hasAuthorship W4309185737A5059866539 @default.
- W4309185737 hasAuthorship W4309185737A5064126602 @default.
- W4309185737 hasAuthorship W4309185737A5066274184 @default.
- W4309185737 hasAuthorship W4309185737A5071439155 @default.
- W4309185737 hasAuthorship W4309185737A5080799305 @default.
- W4309185737 hasAuthorship W4309185737A5089174509 @default.
- W4309185737 hasAuthorship W4309185737A5089456277 @default.
- W4309185737 hasBestOaLocation W43091857371 @default.
- W4309185737 hasConcept C105702510 @default.
- W4309185737 hasConcept C121157162 @default.
- W4309185737 hasConcept C126322002 @default.
- W4309185737 hasConcept C126838900 @default.
- W4309185737 hasConcept C164705383 @default.
- W4309185737 hasConcept C2777607188 @default.
- W4309185737 hasConcept C2778198053 @default.
- W4309185737 hasConcept C2779902710 @default.
- W4309185737 hasConcept C2779951007 @default.
- W4309185737 hasConcept C2989005 @default.
- W4309185737 hasConcept C58471807 @default.
- W4309185737 hasConcept C67139541 @default.
- W4309185737 hasConcept C71924100 @default.
- W4309185737 hasConcept C76318530 @default.
- W4309185737 hasConcept C78085059 @default.
- W4309185737 hasConceptScore W4309185737C105702510 @default.
- W4309185737 hasConceptScore W4309185737C121157162 @default.
- W4309185737 hasConceptScore W4309185737C126322002 @default.
- W4309185737 hasConceptScore W4309185737C126838900 @default.
- W4309185737 hasConceptScore W4309185737C164705383 @default.
- W4309185737 hasConceptScore W4309185737C2777607188 @default.
- W4309185737 hasConceptScore W4309185737C2778198053 @default.
- W4309185737 hasConceptScore W4309185737C2779902710 @default.
- W4309185737 hasConceptScore W4309185737C2779951007 @default.
- W4309185737 hasConceptScore W4309185737C2989005 @default.
- W4309185737 hasConceptScore W4309185737C58471807 @default.
- W4309185737 hasConceptScore W4309185737C67139541 @default.
- W4309185737 hasConceptScore W4309185737C71924100 @default.
- W4309185737 hasConceptScore W4309185737C76318530 @default.
- W4309185737 hasConceptScore W4309185737C78085059 @default.
- W4309185737 hasIssue "11" @default.
- W4309185737 hasLocation W43091857371 @default.
- W4309185737 hasLocation W43091857372 @default.
- W4309185737 hasOpenAccess W4309185737 @default.
- W4309185737 hasPrimaryLocation W43091857371 @default.
- W4309185737 hasRelatedWork W2084731390 @default.