Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309232462> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W4309232462 endingPage "627" @default.
- W4309232462 startingPage "627" @default.
- W4309232462 abstract "Purpose: Increasing evidence reinforces the benefits of reduction of low-density lipoprotein (LDL-C) levels on cardiovascular outcomes. Different targets are suggested based on cardiovascular risk (CVR). According to the current European guidelines, a goal of LDL-C≤ 115mg/dL is desirable for patients with low-moderate CVR. However, a high percentage of these patients are far from this target. Nutraceuticals are “food supplements” that may help to achieve this goal in this population. In this retrospective analysis, we evaluate the effects of dietary supplementation with a novel monacolin/berberine/bergamot nutraceutical formulation on plasma lipid levels of subjects with low-moderate hypercholesterolemia who are not treated with conventional drug or other dietary supplements. Patients and Methods:526 adult patients with hypercholesterolemia were retrospectively selected from the database of participant family practitioners according to prespecified criteria. All selected patients had a baseline and 30-day value of total cholesterol (TC), LDL-C, high-density lipoprotein cholesterol, triglycerides, C-reactive protein, and transaminases and have started a dietary supplementation with this novel nutraceutical. Similarly, 104 subjects with comparable clinical features but not treated with any supplements were also selected. Results:At 30-day, the administration of nutraceuticals was associated with a significant reduction of LDL-C (124 ± 14 vs. 100 ± 13 mg/dL, Δ 24.5mg, p-value <0.0001) and TC levels (210 ± 56 vs. 187 ± 60, p-value < 0.0001), in the absence of a significant change of transaminase levels. No side effects were reported in the database during the observation period. Conclusion: This novel nutraceutical is an effective dietary supplement to achieve a significant and early LDL-C reduction in patients with hypercholesterolemia at low-moderate CVR.Keywords:Cardiovascular Risk; Hypercholesterolemia; Nutraceuticals" @default.
- W4309232462 created "2022-11-24" @default.
- W4309232462 creator A5000811538 @default.
- W4309232462 creator A5023289885 @default.
- W4309232462 creator A5035857177 @default.
- W4309232462 creator A5049562211 @default.
- W4309232462 creator A5050196447 @default.
- W4309232462 creator A5068660181 @default.
- W4309232462 creator A5070014524 @default.
- W4309232462 creator A5089522910 @default.
- W4309232462 date "2022-11-17" @default.
- W4309232462 modified "2023-09-30" @default.
- W4309232462 title "Effectiveness in the short-term of a novel nutraceutical for the management of hypercholesterolemia: an observational multicenter primary care experience" @default.
- W4309232462 doi "https://doi.org/10.31989/ffhd.v12i11.1023" @default.
- W4309232462 hasPublicationYear "2022" @default.
- W4309232462 type Work @default.
- W4309232462 citedByCount "0" @default.
- W4309232462 crossrefType "journal-article" @default.
- W4309232462 hasAuthorship W4309232462A5000811538 @default.
- W4309232462 hasAuthorship W4309232462A5023289885 @default.
- W4309232462 hasAuthorship W4309232462A5035857177 @default.
- W4309232462 hasAuthorship W4309232462A5049562211 @default.
- W4309232462 hasAuthorship W4309232462A5050196447 @default.
- W4309232462 hasAuthorship W4309232462A5068660181 @default.
- W4309232462 hasAuthorship W4309232462A5070014524 @default.
- W4309232462 hasAuthorship W4309232462A5089522910 @default.
- W4309232462 hasBestOaLocation W43092324621 @default.
- W4309232462 hasConcept C126322002 @default.
- W4309232462 hasConcept C142724271 @default.
- W4309232462 hasConcept C17857428 @default.
- W4309232462 hasConcept C23131810 @default.
- W4309232462 hasConcept C2778163477 @default.
- W4309232462 hasConcept C71924100 @default.
- W4309232462 hasConceptScore W4309232462C126322002 @default.
- W4309232462 hasConceptScore W4309232462C142724271 @default.
- W4309232462 hasConceptScore W4309232462C17857428 @default.
- W4309232462 hasConceptScore W4309232462C23131810 @default.
- W4309232462 hasConceptScore W4309232462C2778163477 @default.
- W4309232462 hasConceptScore W4309232462C71924100 @default.
- W4309232462 hasIssue "11" @default.
- W4309232462 hasLocation W43092324621 @default.
- W4309232462 hasOpenAccess W4309232462 @default.
- W4309232462 hasPrimaryLocation W43092324621 @default.
- W4309232462 hasRelatedWork W2004987327 @default.
- W4309232462 hasRelatedWork W2032958076 @default.
- W4309232462 hasRelatedWork W2035331946 @default.
- W4309232462 hasRelatedWork W2072909849 @default.
- W4309232462 hasRelatedWork W2090982939 @default.
- W4309232462 hasRelatedWork W2142830861 @default.
- W4309232462 hasRelatedWork W2419086010 @default.
- W4309232462 hasRelatedWork W2765980456 @default.
- W4309232462 hasRelatedWork W2976382042 @default.
- W4309232462 hasRelatedWork W3197683400 @default.
- W4309232462 hasVolume "12" @default.
- W4309232462 isParatext "false" @default.
- W4309232462 isRetracted "false" @default.
- W4309232462 workType "article" @default.