Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309264285> ?p ?o ?g. }
- W4309264285 endingPage "e1010919" @default.
- W4309264285 startingPage "e1010919" @default.
- W4309264285 abstract "Cerebral malaria (CM) is one of the leading causes of death due to malaria. It is characterised by coma, presence of asexual parasites in blood smear, and absence of any other reason that can cause encephalopathy. The fatality rate for CM is high, and those who survive CM often experience long-term sequelae, including cognitive and motor dysfunctions. It is unclear how parasites sequestered in the lumen of endothelial cells of the blood–brain barrier (BBB), and localised breakdown of BBB can manifest gross physiological changes across the brain. The pathological changes associated with CM are mainly due to the dysregulation of inflammatory and coagulation pathways. Other factors like host and parasite genetics, transmission intensity, and the host’s immune status are likely to play a role in the development and progression of CM. This work focuses on the pathological mechanisms underlying CM. Insights from humans, mice, and in vitro studies have been summarised to present a cohesive understanding of molecular mechanisms involved in CM pathology." @default.
- W4309264285 created "2022-11-25" @default.
- W4309264285 creator A5050237671 @default.
- W4309264285 creator A5081357963 @default.
- W4309264285 date "2022-11-17" @default.
- W4309264285 modified "2023-09-25" @default.
- W4309264285 title "Dissecting the mechanisms of pathogenesis in cerebral malaria" @default.
- W4309264285 cites W1522963829 @default.
- W4309264285 cites W1581767355 @default.
- W4309264285 cites W1622422817 @default.
- W4309264285 cites W1968099474 @default.
- W4309264285 cites W1979215660 @default.
- W4309264285 cites W1979493897 @default.
- W4309264285 cites W1986559839 @default.
- W4309264285 cites W1993655373 @default.
- W4309264285 cites W1998966218 @default.
- W4309264285 cites W2005234042 @default.
- W4309264285 cites W2018122290 @default.
- W4309264285 cites W2030707725 @default.
- W4309264285 cites W2034270761 @default.
- W4309264285 cites W2035280000 @default.
- W4309264285 cites W2039976430 @default.
- W4309264285 cites W2051140555 @default.
- W4309264285 cites W2051664736 @default.
- W4309264285 cites W2056401840 @default.
- W4309264285 cites W2057463574 @default.
- W4309264285 cites W2061183950 @default.
- W4309264285 cites W2065346047 @default.
- W4309264285 cites W2066913173 @default.
- W4309264285 cites W2076139670 @default.
- W4309264285 cites W2076216675 @default.
- W4309264285 cites W2082450214 @default.
- W4309264285 cites W2091997943 @default.
- W4309264285 cites W2101286451 @default.
- W4309264285 cites W2106228560 @default.
- W4309264285 cites W2117132127 @default.
- W4309264285 cites W2125411036 @default.
- W4309264285 cites W2134281092 @default.
- W4309264285 cites W2138889905 @default.
- W4309264285 cites W2146384437 @default.
- W4309264285 cites W2147266392 @default.
- W4309264285 cites W2151243449 @default.
- W4309264285 cites W2152846661 @default.
- W4309264285 cites W2157575017 @default.
- W4309264285 cites W2160945791 @default.
- W4309264285 cites W2165158644 @default.
- W4309264285 cites W2165492931 @default.
- W4309264285 cites W2463298498 @default.
- W4309264285 cites W2591751046 @default.
- W4309264285 cites W2594837180 @default.
- W4309264285 cites W2739307655 @default.
- W4309264285 cites W2767879960 @default.
- W4309264285 cites W2887764658 @default.
- W4309264285 cites W2973915753 @default.
- W4309264285 cites W2975847539 @default.
- W4309264285 cites W2996553563 @default.
- W4309264285 cites W2999348284 @default.
- W4309264285 cites W3044365302 @default.
- W4309264285 cites W4211101162 @default.
- W4309264285 cites W4236042401 @default.
- W4309264285 doi "https://doi.org/10.1371/journal.ppat.1010919" @default.
- W4309264285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36395123" @default.
- W4309264285 hasPublicationYear "2022" @default.
- W4309264285 type Work @default.
- W4309264285 citedByCount "3" @default.
- W4309264285 countsByYear W43092642852023 @default.
- W4309264285 crossrefType "journal-article" @default.
- W4309264285 hasAuthorship W4309264285A5050237671 @default.
- W4309264285 hasAuthorship W4309264285A5081357963 @default.
- W4309264285 hasBestOaLocation W43092642851 @default.
- W4309264285 hasConcept C111472728 @default.
- W4309264285 hasConcept C126322002 @default.
- W4309264285 hasConcept C138885662 @default.
- W4309264285 hasConcept C142724271 @default.
- W4309264285 hasConcept C169760540 @default.
- W4309264285 hasConcept C203014093 @default.
- W4309264285 hasConcept C207886595 @default.
- W4309264285 hasConcept C2776914184 @default.
- W4309264285 hasConcept C2778048844 @default.
- W4309264285 hasConcept C2778371730 @default.
- W4309264285 hasConcept C2778402981 @default.
- W4309264285 hasConcept C2778621155 @default.
- W4309264285 hasConcept C2780942790 @default.
- W4309264285 hasConcept C2908793570 @default.
- W4309264285 hasConcept C529278444 @default.
- W4309264285 hasConcept C71924100 @default.
- W4309264285 hasConcept C86803240 @default.
- W4309264285 hasConcept C8891405 @default.
- W4309264285 hasConcept C89611455 @default.
- W4309264285 hasConceptScore W4309264285C111472728 @default.
- W4309264285 hasConceptScore W4309264285C126322002 @default.
- W4309264285 hasConceptScore W4309264285C138885662 @default.
- W4309264285 hasConceptScore W4309264285C142724271 @default.
- W4309264285 hasConceptScore W4309264285C169760540 @default.
- W4309264285 hasConceptScore W4309264285C203014093 @default.
- W4309264285 hasConceptScore W4309264285C207886595 @default.
- W4309264285 hasConceptScore W4309264285C2776914184 @default.
- W4309264285 hasConceptScore W4309264285C2778048844 @default.