FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309271194> ?p ?o ?g. }

• W4309271194 abstract "Background: The purpose of this study is to identify and characterize ocular adverse events (AEs) that are significantly associated with anti-VEGF drugs for treatment of neovascular age-related macular degeneration and compare the differences between each drug, and provide clinical reference. Methods: Ocular AEs submitted to the US Food and Drug Administration were analyzed to map the safety profile of anti-VEGF drugs. The Pharmacovigilance tools used for the quantitative detection of signals were reporting odds ratio and bayesian confidence propagation neural network. Results: A total of 10,608,503 AE reports were retrieved from FAERS, with 20,836 for ranibizumab, 19,107 for aflibercept, and 2,442 for brolucizumab between the reporting period of Q1, 2004 and Q3, 2021. We found and analyzed the different AEs with the strongest signal in each drug-ranibizumab-macular ischaemia (ROR = 205.27, IC-2SD = 3.70), retinal pigment epithelial tear (ROR = 836.54, IC-2SD = 7.19); aflibercept-intraocular pressure increased (ROR = 31.09, IC-2SD = 4.61), endophthalmitis (ROR = 178.27, IC-2SD = 6.70); brolucizumab-retinal vasculitis (ROR = 2930.41, IC-2SD = 7.47) and/or retinal artery occlusion (ROR = 391.11, IC-2SD = 6.10), dry eye (ROR = 12.48, IC-2SD = 2.88). Conclusion: The presence of AEs should bring clinical attention. The use of anti-VEGF drugs should be based on the patient's underlying or present medical condition to reduce any adverse event associated with the treatment." @default.
• W4309271194 created "2022-11-25" @default.
• W4309271194 creator A5000390508 @default.
• W4309271194 creator A5016230509 @default.
• W4309271194 creator A5032371361 @default.
• W4309271194 creator A5034530515 @default.
• W4309271194 creator A5046676286 @default.
• W4309271194 creator A5059161383 @default.
• W4309271194 creator A5066739281 @default.
• W4309271194 creator A5084787075 @default.
• W4309271194 date "2022-11-18" @default.
• W4309271194 modified "2023-09-30" @default.
• W4309271194 title "Ocular adverse events associated with anti-VEGF therapy: A pharmacovigilance study of the FDA adverse event reporting system (FAERS)" @default.
• W4309271194 cites W1789824814 @default.
• W4309271194 cites W1897755666 @default.
• W4309271194 cites W1968666664 @default.
• W4309271194 cites W1976922940 @default.
• W4309271194 cites W1987699263 @default.
• W4309271194 cites W1992264850 @default.
• W4309271194 cites W1995822290 @default.
• W4309271194 cites W1996488113 @default.
• W4309271194 cites W1999970995 @default.
• W4309271194 cites W1999981668 @default.
• W4309271194 cites W2002986738 @default.
• W4309271194 cites W2004117352 @default.
• W4309271194 cites W2015190847 @default.
• W4309271194 cites W2016159338 @default.
• W4309271194 cites W2017136158 @default.
• W4309271194 cites W2024725915 @default.
• W4309271194 cites W2031737722 @default.
• W4309271194 cites W2048625080 @default.
• W4309271194 cites W2055903764 @default.
• W4309271194 cites W2057196912 @default.
• W4309271194 cites W2057266151 @default.
• W4309271194 cites W2066744889 @default.
• W4309271194 cites W2068742492 @default.
• W4309271194 cites W2081063786 @default.
• W4309271194 cites W2091989599 @default.
• W4309271194 cites W2096547439 @default.
• W4309271194 cites W2119086529 @default.
• W4309271194 cites W2150018887 @default.
• W4309271194 cites W2159681472 @default.
• W4309271194 cites W2160226180 @default.
• W4309271194 cites W2165439370 @default.
• W4309271194 cites W2274444581 @default.
• W4309271194 cites W2287587792 @default.
• W4309271194 cites W2316516002 @default.
• W4309271194 cites W2408943173 @default.
• W4309271194 cites W2524064376 @default.
• W4309271194 cites W2738996050 @default.
• W4309271194 cites W2747725012 @default.
• W4309271194 cites W2789582799 @default.
• W4309271194 cites W2936430874 @default.
• W4309271194 cites W2944838373 @default.
• W4309271194 cites W2947161633 @default.
• W4309271194 cites W2995304241 @default.
• W4309271194 cites W3005487212 @default.
• W4309271194 cites W3011413299 @default.
• W4309271194 cites W3014659623 @default.
• W4309271194 cites W3016654382 @default.
• W4309271194 cites W3017504588 @default.
• W4309271194 cites W3029325193 @default.
• W4309271194 cites W3113485358 @default.
• W4309271194 cites W3157686683 @default.
• W4309271194 cites W3159164145 @default.
• W4309271194 cites W3202564256 @default.
• W4309271194 doi "https://doi.org/10.3389/fphar.2022.1017889" @default.
• W4309271194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36467087" @default.
• W4309271194 hasPublicationYear "2022" @default.
• W4309271194 type Work @default.
• W4309271194 citedByCount "4" @default.
• W4309271194 countsByYear W43092711942023 @default.
• W4309271194 crossrefType "journal-article" @default.
• W4309271194 hasAuthorship W4309271194A5000390508 @default.
• W4309271194 hasAuthorship W4309271194A5016230509 @default.
• W4309271194 hasAuthorship W4309271194A5032371361 @default.
• W4309271194 hasAuthorship W4309271194A5034530515 @default.
• W4309271194 hasAuthorship W4309271194A5046676286 @default.
• W4309271194 hasAuthorship W4309271194A5059161383 @default.
• W4309271194 hasAuthorship W4309271194A5066739281 @default.
• W4309271194 hasAuthorship W4309271194A5084787075 @default.
• W4309271194 hasBestOaLocation W43092711941 @default.
• W4309271194 hasConcept C118487528 @default.
• W4309271194 hasConcept C126322002 @default.
• W4309271194 hasConcept C197934379 @default.
• W4309271194 hasConcept C2775888743 @default.
• W4309271194 hasConcept C2776403814 @default.
• W4309271194 hasConcept C2776694085 @default.
• W4309271194 hasConcept C2777105317 @default.
• W4309271194 hasConcept C2777235844 @default.
• W4309271194 hasConcept C2777802072 @default.
• W4309271194 hasConcept C2778749236 @default.
• W4309271194 hasConcept C2781100027 @default.
• W4309271194 hasConcept C57658597 @default.
• W4309271194 hasConcept C71924100 @default.
• W4309271194 hasConcept C98274493 @default.
• W4309271194 hasConceptScore W4309271194C118487528 @default.
• W4309271194 hasConceptScore W4309271194C126322002 @default.
• W4309271194 hasConceptScore W4309271194C197934379 @default.
• W4309271194 hasConceptScore W4309271194C2775888743 @default.

• next