Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309294249> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W4309294249 abstract "Herein, we report the development of a highly enantioselective aminoallylation reaction of both aldehyde and ketone electrophiles through the Cu-catalyzed reductive coupling of N-substituted allenes (allenamides). Through optimization of the allenamide to avoid an on-cycle rearrangement, high enantioselectivities could be obtained for a variety of ketone and aldehyde electrophiles in up to >99% ee and >98:2 anti:syn diastereoselectivities. Use of the acyclic allenamides described in this report selectively generated anti-diastereomers in contrast to cyclic allenamides that were previously shown to favor the syn form. Rationale for this change in diastereoselectivity and synthetic applications are also presented." @default.
- W4309294249 created "2022-11-25" @default.
- W4309294249 creator A5026768131 @default.
- W4309294249 creator A5047532376 @default.
- W4309294249 creator A5083220867 @default.
- W4309294249 date "2022-11-17" @default.
- W4309294249 modified "2023-10-17" @default.
- W4309294249 title "A Unified Approach to the Aminoallylation of Carbonyl Compounds Through Cu-Catalyzed Enantioselective Reductive Coupling of Allenamides" @default.
- W4309294249 doi "https://doi.org/10.26434/chemrxiv-2022-94pg8" @default.
- W4309294249 hasPublicationYear "2022" @default.
- W4309294249 type Work @default.
- W4309294249 citedByCount "2" @default.
- W4309294249 countsByYear W43092942492023 @default.
- W4309294249 crossrefType "posted-content" @default.
- W4309294249 hasAuthorship W4309294249A5026768131 @default.
- W4309294249 hasAuthorship W4309294249A5047532376 @default.
- W4309294249 hasAuthorship W4309294249A5083220867 @default.
- W4309294249 hasBestOaLocation W43092942491 @default.
- W4309294249 hasConcept C131584629 @default.
- W4309294249 hasConcept C138716334 @default.
- W4309294249 hasConcept C146686406 @default.
- W4309294249 hasConcept C161790260 @default.
- W4309294249 hasConcept C178790620 @default.
- W4309294249 hasConcept C185592680 @default.
- W4309294249 hasConcept C191897082 @default.
- W4309294249 hasConcept C192562407 @default.
- W4309294249 hasConcept C21951064 @default.
- W4309294249 hasConcept C2777738585 @default.
- W4309294249 hasConcept C2779825165 @default.
- W4309294249 hasConcept C50027330 @default.
- W4309294249 hasConceptScore W4309294249C131584629 @default.
- W4309294249 hasConceptScore W4309294249C138716334 @default.
- W4309294249 hasConceptScore W4309294249C146686406 @default.
- W4309294249 hasConceptScore W4309294249C161790260 @default.
- W4309294249 hasConceptScore W4309294249C178790620 @default.
- W4309294249 hasConceptScore W4309294249C185592680 @default.
- W4309294249 hasConceptScore W4309294249C191897082 @default.
- W4309294249 hasConceptScore W4309294249C192562407 @default.
- W4309294249 hasConceptScore W4309294249C21951064 @default.
- W4309294249 hasConceptScore W4309294249C2777738585 @default.
- W4309294249 hasConceptScore W4309294249C2779825165 @default.
- W4309294249 hasConceptScore W4309294249C50027330 @default.
- W4309294249 hasFunder F4320306076 @default.
- W4309294249 hasFunder F4320311096 @default.
- W4309294249 hasLocation W43092942491 @default.
- W4309294249 hasOpenAccess W4309294249 @default.
- W4309294249 hasPrimaryLocation W43092942491 @default.
- W4309294249 hasRelatedWork W1968710126 @default.
- W4309294249 hasRelatedWork W1975248319 @default.
- W4309294249 hasRelatedWork W1982446660 @default.
- W4309294249 hasRelatedWork W1983514663 @default.
- W4309294249 hasRelatedWork W2011389557 @default.
- W4309294249 hasRelatedWork W2154956352 @default.
- W4309294249 hasRelatedWork W2896852757 @default.
- W4309294249 hasRelatedWork W2952410092 @default.
- W4309294249 hasRelatedWork W2953052257 @default.
- W4309294249 hasRelatedWork W4309294249 @default.
- W4309294249 isParatext "false" @default.
- W4309294249 isRetracted "false" @default.
- W4309294249 workType "article" @default.