Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309310080> ?p ?o ?g. }
- W4309310080 abstract "Plant bacterial disease is a complex outcome achieved through a combination of virulence factors that are activated during infection. However, the common virulence factors across diverse plant pathogens are largely uncharacterized. Here, we established a pan-genome shared across the following plant pathogens: Burkholderia glumae, Ralstonia solanacearum, and Xanthomonas oryzae pv. oryzae. By overlaying in planta transcriptomes onto the pan-genome, we investigated the expression profiles of common genes during infection. We found over 70% of identical patterns for genes commonly expressed by the pathogens in different plant hosts or infection sites. Co-expression patterns revealed the activation of a signal transduction cascade to recognize and respond to external changes within hosts. Using mutagenesis, we uncovered a relationship between bacterial virulence and functions highly conserved and shared in the studied genomes of the bacterial phytopathogens, including flagellar biosynthesis protein, C4-dicarboxylate ABC transporter, 2-methylisocitrate lyase, and protocatechuate 3,4-dioxygenase (PCD). In particular, the disruption of PCD gene led to attenuated virulence in all pathogens and significantly affected phytotoxin production in B. glumae. This PCD gene was ubiquitously distributed in most plant pathogens with high homology. In conclusion, our results provide cross-species in planta models for identifying common virulence factors, which can be useful for the protection of crops against diverse pathogens." @default.
- W4309310080 created "2022-11-26" @default.
- W4309310080 creator A5015827292 @default.
- W4309310080 creator A5017305706 @default.
- W4309310080 creator A5020879057 @default.
- W4309310080 creator A5027383868 @default.
- W4309310080 creator A5034345010 @default.
- W4309310080 creator A5040893153 @default.
- W4309310080 creator A5050704650 @default.
- W4309310080 creator A5060949003 @default.
- W4309310080 creator A5066646408 @default.
- W4309310080 creator A5088882066 @default.
- W4309310080 date "2022-11-16" @default.
- W4309310080 modified "2023-10-09" @default.
- W4309310080 title "Genome-guided comparative in planta transcriptome analyses for identifying cross-species common virulence factors in bacterial phytopathogens" @default.
- W4309310080 cites W1922881108 @default.
- W4309310080 cites W1932609322 @default.
- W4309310080 cites W1935891504 @default.
- W4309310080 cites W1942230840 @default.
- W4309310080 cites W1966039796 @default.
- W4309310080 cites W1973633554 @default.
- W4309310080 cites W1975301430 @default.
- W4309310080 cites W1977557566 @default.
- W4309310080 cites W1977564187 @default.
- W4309310080 cites W1979889123 @default.
- W4309310080 cites W1981770628 @default.
- W4309310080 cites W1991619286 @default.
- W4309310080 cites W1996142621 @default.
- W4309310080 cites W2002275601 @default.
- W4309310080 cites W2011280150 @default.
- W4309310080 cites W2029541102 @default.
- W4309310080 cites W2033772934 @default.
- W4309310080 cites W2036236484 @default.
- W4309310080 cites W2055043489 @default.
- W4309310080 cites W2074118291 @default.
- W4309310080 cites W2074468058 @default.
- W4309310080 cites W2077704006 @default.
- W4309310080 cites W2085871618 @default.
- W4309310080 cites W2090326670 @default.
- W4309310080 cites W2097321270 @default.
- W4309310080 cites W2098567697 @default.
- W4309310080 cites W2105783449 @default.
- W4309310080 cites W2111174026 @default.
- W4309310080 cites W2114111406 @default.
- W4309310080 cites W2114781992 @default.
- W4309310080 cites W2119034410 @default.
- W4309310080 cites W2120649174 @default.
- W4309310080 cites W2123116361 @default.
- W4309310080 cites W2123208777 @default.
- W4309310080 cites W2123618614 @default.
- W4309310080 cites W2129289175 @default.
- W4309310080 cites W2136225763 @default.
- W4309310080 cites W2137034263 @default.
- W4309310080 cites W2143242138 @default.
- W4309310080 cites W2145947053 @default.
- W4309310080 cites W2148195755 @default.
- W4309310080 cites W2150550043 @default.
- W4309310080 cites W2152311551 @default.
- W4309310080 cites W2152921520 @default.
- W4309310080 cites W2166986886 @default.
- W4309310080 cites W2168666828 @default.
- W4309310080 cites W2211558999 @default.
- W4309310080 cites W2419568746 @default.
- W4309310080 cites W2558656420 @default.
- W4309310080 cites W2594713503 @default.
- W4309310080 cites W2765578562 @default.
- W4309310080 cites W2908253050 @default.
- W4309310080 cites W2951544797 @default.
- W4309310080 cites W3125194737 @default.
- W4309310080 cites W3152922322 @default.
- W4309310080 cites W4241325523 @default.
- W4309310080 cites W1996887018 @default.
- W4309310080 cites W2107616608 @default.
- W4309310080 doi "https://doi.org/10.3389/fpls.2022.1030720" @default.
- W4309310080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36466249" @default.
- W4309310080 hasPublicationYear "2022" @default.
- W4309310080 type Work @default.
- W4309310080 citedByCount "0" @default.
- W4309310080 crossrefType "journal-article" @default.
- W4309310080 hasAuthorship W4309310080A5015827292 @default.
- W4309310080 hasAuthorship W4309310080A5017305706 @default.
- W4309310080 hasAuthorship W4309310080A5020879057 @default.
- W4309310080 hasAuthorship W4309310080A5027383868 @default.
- W4309310080 hasAuthorship W4309310080A5034345010 @default.
- W4309310080 hasAuthorship W4309310080A5040893153 @default.
- W4309310080 hasAuthorship W4309310080A5050704650 @default.
- W4309310080 hasAuthorship W4309310080A5060949003 @default.
- W4309310080 hasAuthorship W4309310080A5066646408 @default.
- W4309310080 hasAuthorship W4309310080A5088882066 @default.
- W4309310080 hasBestOaLocation W43093100801 @default.
- W4309310080 hasConcept C104317684 @default.
- W4309310080 hasConcept C141231307 @default.
- W4309310080 hasConcept C150194340 @default.
- W4309310080 hasConcept C162317418 @default.
- W4309310080 hasConcept C2776460866 @default.
- W4309310080 hasConcept C2776964914 @default.
- W4309310080 hasConcept C2780562374 @default.
- W4309310080 hasConcept C2780675535 @default.
- W4309310080 hasConcept C2780746887 @default.
- W4309310080 hasConcept C54355233 @default.