Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309349815> ?p ?o ?g. }
- W4309349815 abstract "Abstract Background So far, limited studies have focused on the role of Macrophages (MQs) in the development or progression of celiac disease (CD). Researchers believe that increasing knowledge about the function of MQs in inflammatory disorders plays a critical role in finding a new treatment for these kinds of diseases. Main body CD is a permanent autoimmune intestinal disorder triggered by gluten exposure in predisposed individuals. This disorder happens due to the loss of intestinal epithelial barrier integrity characterized by dysregulated innate and adaptive immune responses. MQs are known as key players of the innate immune system that link innate and adaptive immunity. MQs of human intestinal lamina propria participate in maintaining tissue homeostasis, and also intestinal inflammation development. Previous studies suggested that gliadin triggers a proinflammatory phenotype (M1 MQ) in human primary MQs. Moreover, M2‐related immunosuppressive mediators are also present in CD. In fact, CD patients present an impaired transition from pro‐inflammatory to anti‐inflammatory responses due to inappropriate responses to gliadin peptides. Conclusion The M1/M2 MQs polarization balancing regulators can be considered novel therapeutic targets for celiac disease." @default.
- W4309349815 created "2022-11-26" @default.
- W4309349815 creator A5001118300 @default.
- W4309349815 creator A5011421631 @default.
- W4309349815 creator A5011528450 @default.
- W4309349815 creator A5037895047 @default.
- W4309349815 creator A5039019858 @default.
- W4309349815 creator A5042286429 @default.
- W4309349815 creator A5047959946 @default.
- W4309349815 creator A5048643037 @default.
- W4309349815 creator A5056121031 @default.
- W4309349815 date "2022-11-16" @default.
- W4309349815 modified "2023-09-26" @default.
- W4309349815 title "The modulation of macrophage subsets in celiac disease pathogenesis" @default.
- W4309349815 cites W1484263832 @default.
- W4309349815 cites W1531267945 @default.
- W4309349815 cites W1560364130 @default.
- W4309349815 cites W1640399046 @default.
- W4309349815 cites W1918028620 @default.
- W4309349815 cites W1926772041 @default.
- W4309349815 cites W1964431874 @default.
- W4309349815 cites W1986077595 @default.
- W4309349815 cites W1988232165 @default.
- W4309349815 cites W1995482748 @default.
- W4309349815 cites W2003801599 @default.
- W4309349815 cites W2008403719 @default.
- W4309349815 cites W2012850942 @default.
- W4309349815 cites W2016633231 @default.
- W4309349815 cites W2019180307 @default.
- W4309349815 cites W2036564362 @default.
- W4309349815 cites W2060654250 @default.
- W4309349815 cites W2061123122 @default.
- W4309349815 cites W2070995184 @default.
- W4309349815 cites W2072462631 @default.
- W4309349815 cites W2089573422 @default.
- W4309349815 cites W2129991968 @default.
- W4309349815 cites W2133929474 @default.
- W4309349815 cites W2139114869 @default.
- W4309349815 cites W2150067149 @default.
- W4309349815 cites W2178411752 @default.
- W4309349815 cites W2560534441 @default.
- W4309349815 cites W2570925328 @default.
- W4309349815 cites W2577621077 @default.
- W4309349815 cites W2586115964 @default.
- W4309349815 cites W2594732596 @default.
- W4309349815 cites W2613625890 @default.
- W4309349815 cites W2616238336 @default.
- W4309349815 cites W2765299453 @default.
- W4309349815 cites W2782685575 @default.
- W4309349815 cites W2786954262 @default.
- W4309349815 cites W2796313978 @default.
- W4309349815 cites W2891824977 @default.
- W4309349815 cites W2900582712 @default.
- W4309349815 cites W2937061963 @default.
- W4309349815 cites W2937717169 @default.
- W4309349815 cites W2937921992 @default.
- W4309349815 cites W2945781043 @default.
- W4309349815 cites W2951500272 @default.
- W4309349815 cites W2963656050 @default.
- W4309349815 cites W2963702053 @default.
- W4309349815 cites W2965186303 @default.
- W4309349815 cites W2981393920 @default.
- W4309349815 cites W2985062150 @default.
- W4309349815 cites W2988351590 @default.
- W4309349815 cites W3004735824 @default.
- W4309349815 cites W3009405970 @default.
- W4309349815 cites W3016165881 @default.
- W4309349815 cites W3028869453 @default.
- W4309349815 cites W3040643851 @default.
- W4309349815 cites W3047596096 @default.
- W4309349815 cites W3124068513 @default.
- W4309349815 cites W3127579046 @default.
- W4309349815 cites W3128983293 @default.
- W4309349815 cites W3129370137 @default.
- W4309349815 cites W3134545765 @default.
- W4309349815 cites W3181736173 @default.
- W4309349815 cites W3193765659 @default.
- W4309349815 cites W3196856833 @default.
- W4309349815 cites W3203809982 @default.
- W4309349815 cites W4210849836 @default.
- W4309349815 cites W4223557025 @default.
- W4309349815 cites W4236836788 @default.
- W4309349815 cites W4293658213 @default.
- W4309349815 doi "https://doi.org/10.1002/iid3.741" @default.
- W4309349815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36444633" @default.
- W4309349815 hasPublicationYear "2022" @default.
- W4309349815 type Work @default.
- W4309349815 citedByCount "1" @default.
- W4309349815 countsByYear W43093498152023 @default.
- W4309349815 crossrefType "journal-article" @default.
- W4309349815 hasAuthorship W4309349815A5001118300 @default.
- W4309349815 hasAuthorship W4309349815A5011421631 @default.
- W4309349815 hasAuthorship W4309349815A5011528450 @default.
- W4309349815 hasAuthorship W4309349815A5037895047 @default.
- W4309349815 hasAuthorship W4309349815A5039019858 @default.
- W4309349815 hasAuthorship W4309349815A5042286429 @default.
- W4309349815 hasAuthorship W4309349815A5047959946 @default.
- W4309349815 hasAuthorship W4309349815A5048643037 @default.
- W4309349815 hasAuthorship W4309349815A5056121031 @default.
- W4309349815 hasBestOaLocation W43093498151 @default.