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- W4309355790 abstract "Henoch–Schonlein purpura (HSP) nephritis and IgA nephropathy are the two most common glomerular diseases occurring in children characterized by predominant glomerular IgA deposits. While IgA nephropathy is a renally limited glomerular disorder, HSP nephritis is associated with extrarenal involvement including the typical rash, arthralgia, arthritis, and gastrointestinal involvement. HSP are anecdotal reports and despite extensive investigation there is no clear pathogen that is accepted as a trigger for the clinical manifestations of HSP. IgA nephropathy comprises mesangial deposition of IgA within the glomerulus. The light microscopy findings on renal biopsy in patients with IgA nephropathy can range from near normal appearing glomeruli to a rapidly progressing glomerulonephritis picture with cellular crescents. Limited evidence-based recommendations can be made for the treatment of IgA nephropathy and HSP nephritis in children due to overall lack of controlled low risk of bias studies in this population." @default.
- W4309355790 created "2022-11-26" @default.
- W4309355790 creator A5007303278 @default.
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- W4309355790 date "2022-11-18" @default.
- W4309355790 modified "2023-10-16" @default.
- W4309355790 title "Henoch–Schonlein Purpura Glomerulonephritis and IgA Nephropathy in Children" @default.
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- W4309355790 doi "https://doi.org/10.1002/9781119105954.ch68" @default.
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