Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309356194> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4309356194 endingPage "12" @default.
- W4309356194 startingPage "1" @default.
- W4309356194 abstract "Two major issues have been debated throughout the history of drug metabolism, and are still disputed to some degree. One is the name itself, the other is the physiological purpose of “drug” metabolism. Many current students of metabolism are surprised to learn that drug metabolism experiments were first conducted and published more than 200 years ago, first in dogs in 1824 and next in humans in 1841. Glycine conjugation has the honor of being the first-described metabolism reaction. Because of advances in analytical technologies and biochemical methods, metabolism studies took off starting in about 1950. For the first time, the cofactors of the enzymatic reactions were fully elucidated, and the enzymatic biosynthesis pathways of the cofactors were established. Major advances between 1980–2005 were driven by improved technologies. The major human cytochrome P450 members were identified, purified, and characterized from human liver tissue starting in 1983." @default.
- W4309356194 created "2022-11-26" @default.
- W4309356194 creator A5055235091 @default.
- W4309356194 date "2022-11-18" @default.
- W4309356194 modified "2023-10-16" @default.
- W4309356194 title "Historical Perspective" @default.
- W4309356194 cites W1490329277 @default.
- W4309356194 cites W1498584605 @default.
- W4309356194 cites W1535609664 @default.
- W4309356194 cites W1543649428 @default.
- W4309356194 cites W157997765 @default.
- W4309356194 cites W1591497700 @default.
- W4309356194 cites W174790603 @default.
- W4309356194 cites W1957665457 @default.
- W4309356194 cites W1979993939 @default.
- W4309356194 cites W1980147496 @default.
- W4309356194 cites W1983390126 @default.
- W4309356194 cites W2013675289 @default.
- W4309356194 cites W2032225081 @default.
- W4309356194 cites W2041595680 @default.
- W4309356194 cites W2059118691 @default.
- W4309356194 cites W2062808672 @default.
- W4309356194 cites W2064680168 @default.
- W4309356194 cites W2092116907 @default.
- W4309356194 cites W2112084329 @default.
- W4309356194 cites W2120151491 @default.
- W4309356194 cites W2122721432 @default.
- W4309356194 cites W2139395243 @default.
- W4309356194 cites W2144849809 @default.
- W4309356194 cites W2157353462 @default.
- W4309356194 cites W2163343496 @default.
- W4309356194 cites W2165995367 @default.
- W4309356194 cites W2179955304 @default.
- W4309356194 cites W2395948691 @default.
- W4309356194 cites W2414846001 @default.
- W4309356194 cites W4205969449 @default.
- W4309356194 cites W4240772139 @default.
- W4309356194 cites W4250196649 @default.
- W4309356194 cites W95080166 @default.
- W4309356194 doi "https://doi.org/10.1002/9781119851042.ch1" @default.
- W4309356194 hasPublicationYear "2022" @default.
- W4309356194 type Work @default.
- W4309356194 citedByCount "0" @default.
- W4309356194 crossrefType "other" @default.
- W4309356194 hasAuthorship W4309356194A5055235091 @default.
- W4309356194 hasConcept C181199279 @default.
- W4309356194 hasConcept C197957613 @default.
- W4309356194 hasConcept C526171541 @default.
- W4309356194 hasConcept C55493867 @default.
- W4309356194 hasConcept C62231903 @default.
- W4309356194 hasConcept C86803240 @default.
- W4309356194 hasConcept C89311334 @default.
- W4309356194 hasConceptScore W4309356194C181199279 @default.
- W4309356194 hasConceptScore W4309356194C197957613 @default.
- W4309356194 hasConceptScore W4309356194C526171541 @default.
- W4309356194 hasConceptScore W4309356194C55493867 @default.
- W4309356194 hasConceptScore W4309356194C62231903 @default.
- W4309356194 hasConceptScore W4309356194C86803240 @default.
- W4309356194 hasConceptScore W4309356194C89311334 @default.
- W4309356194 hasLocation W43093561941 @default.
- W4309356194 hasOpenAccess W4309356194 @default.
- W4309356194 hasPrimaryLocation W43093561941 @default.
- W4309356194 hasRelatedWork W1164537646 @default.
- W4309356194 hasRelatedWork W1541331517 @default.
- W4309356194 hasRelatedWork W1584841812 @default.
- W4309356194 hasRelatedWork W1603625312 @default.
- W4309356194 hasRelatedWork W2047764430 @default.
- W4309356194 hasRelatedWork W2079104442 @default.
- W4309356194 hasRelatedWork W2080203695 @default.
- W4309356194 hasRelatedWork W2419414102 @default.
- W4309356194 hasRelatedWork W4381942715 @default.
- W4309356194 hasRelatedWork W966738943 @default.
- W4309356194 isParatext "false" @default.
- W4309356194 isRetracted "false" @default.
- W4309356194 workType "other" @default.