Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309376563> ?p ?o ?g. }
- W4309376563 endingPage "186" @default.
- W4309376563 startingPage "151" @default.
- W4309376563 abstract "The concept of bioadhesive and phase change polymers initially appeared four decades ago and has since become one of the most investigated polymers for drug delivery systems. Some polymeric drug carriers attach to epithelial tissue or mucous membranes (bioadhesion). Epithelial tissues and mucous membranes often serve as possible adhesive sites for bioadhesive/mucoadhesive polymers, increasing the contact time between the drug and the site of action. Bioadhesive drug delivery systems address the drawbacks of conventional drug delivery systems by significantly reducing dosing frequencies and enabling prolonged controlled/sustained and targeted drug release with enhanced bioavailability. Studies have shown that by increasing the residence time at the application site, these carriers improve local therapeutic action and increase the systemic distribution of the drugs. These drug delivery strategies appear to help deal with drugs that are restrictive in oral or other traditional methods of administration, particularly acid-labile drugs or drugs that undergo first-pass metabolism. On the other hand, phase change polymers act by responding to external stimuli such as temperature, pH, light, and electric current. Many applications have been designed to optimize drug delivery based on the stimulus-induced phase change. This chapter attempts to review several aspects of bioadhesive and phase change polymers, their mechanisms, factors affecting them, their classification, and their applications in drug delivery." @default.
- W4309376563 created "2022-11-26" @default.
- W4309376563 creator A5018547823 @default.
- W4309376563 creator A5028335866 @default.
- W4309376563 creator A5047361611 @default.
- W4309376563 creator A5050338675 @default.
- W4309376563 creator A5052491503 @default.
- W4309376563 creator A5057305533 @default.
- W4309376563 creator A5058701155 @default.
- W4309376563 creator A5066373911 @default.
- W4309376563 creator A5075559034 @default.
- W4309376563 date "2023-01-01" @default.
- W4309376563 modified "2023-10-16" @default.
- W4309376563 title "Bioadhesive and phase change polymers for drug delivery" @default.
- W4309376563 cites W1585026215 @default.
- W4309376563 cites W1849681763 @default.
- W4309376563 cites W1966590541 @default.
- W4309376563 cites W1967985930 @default.
- W4309376563 cites W1973548559 @default.
- W4309376563 cites W1977065263 @default.
- W4309376563 cites W1982617677 @default.
- W4309376563 cites W1984335257 @default.
- W4309376563 cites W1990719839 @default.
- W4309376563 cites W1992363526 @default.
- W4309376563 cites W1995475798 @default.
- W4309376563 cites W2001895546 @default.
- W4309376563 cites W2003770685 @default.
- W4309376563 cites W2003936338 @default.
- W4309376563 cites W2004173569 @default.
- W4309376563 cites W2004616899 @default.
- W4309376563 cites W2005638380 @default.
- W4309376563 cites W2009781864 @default.
- W4309376563 cites W2010865418 @default.
- W4309376563 cites W2012407073 @default.
- W4309376563 cites W2014864181 @default.
- W4309376563 cites W2016725811 @default.
- W4309376563 cites W2017289311 @default.
- W4309376563 cites W2019135567 @default.
- W4309376563 cites W2020406291 @default.
- W4309376563 cites W2020935675 @default.
- W4309376563 cites W2021244409 @default.
- W4309376563 cites W2022279350 @default.
- W4309376563 cites W2022359813 @default.
- W4309376563 cites W2029071448 @default.
- W4309376563 cites W2038802821 @default.
- W4309376563 cites W2041880062 @default.
- W4309376563 cites W2042565735 @default.
- W4309376563 cites W2043509791 @default.
- W4309376563 cites W2049312803 @default.
- W4309376563 cites W2052224045 @default.
- W4309376563 cites W2053424786 @default.
- W4309376563 cites W2053448154 @default.
- W4309376563 cites W2057000213 @default.
- W4309376563 cites W2060397516 @default.
- W4309376563 cites W2066416624 @default.
- W4309376563 cites W2070182118 @default.
- W4309376563 cites W2079551453 @default.
- W4309376563 cites W2085250824 @default.
- W4309376563 cites W2087247100 @default.
- W4309376563 cites W2089869065 @default.
- W4309376563 cites W2092502633 @default.
- W4309376563 cites W2093051860 @default.
- W4309376563 cites W2098879162 @default.
- W4309376563 cites W2101059745 @default.
- W4309376563 cites W2105285918 @default.
- W4309376563 cites W2107660675 @default.
- W4309376563 cites W2122011674 @default.
- W4309376563 cites W2127955898 @default.
- W4309376563 cites W2132484465 @default.
- W4309376563 cites W2148648362 @default.
- W4309376563 cites W2156492800 @default.
- W4309376563 cites W2164101908 @default.
- W4309376563 cites W2168459754 @default.
- W4309376563 cites W2186240208 @default.
- W4309376563 cites W2216174252 @default.
- W4309376563 cites W2313244619 @default.
- W4309376563 cites W2330266849 @default.
- W4309376563 cites W23429057 @default.
- W4309376563 cites W2527569309 @default.
- W4309376563 cites W2532588650 @default.
- W4309376563 cites W2535849056 @default.
- W4309376563 cites W2565695863 @default.
- W4309376563 cites W258735800 @default.
- W4309376563 cites W2591871623 @default.
- W4309376563 cites W2594597745 @default.
- W4309376563 cites W2611803514 @default.
- W4309376563 cites W2736459508 @default.
- W4309376563 cites W2741299362 @default.
- W4309376563 cites W2781029745 @default.
- W4309376563 cites W2783867707 @default.
- W4309376563 cites W2797528083 @default.
- W4309376563 cites W2801616202 @default.
- W4309376563 cites W2808431275 @default.
- W4309376563 cites W2808831286 @default.
- W4309376563 cites W2811125510 @default.
- W4309376563 cites W2883065983 @default.
- W4309376563 cites W2889668372 @default.
- W4309376563 cites W2895052671 @default.