FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309387934> ?p ?o ?g. }

• W4309387934 abstract "Abstract Background Although people are more and more aware of the cardiotoxicity caused by immune checkpoint inhibitors (ICIs) in the treatment of lung cancer, its incidence rate has not been systematically analyzed. This study aims to evaluate the incidence of cardiotoxicity related to the ICI therapies for lung cancer, so as to enhance clinicians' attention to cardiotoxicity, implement proper prevention and intervention for high-risk patients, and minimize the risk of cardiac dysfunction during and after completion of therapy. Methods We conducted a systematic literature search for relevant publications in PubMed and Scopus from inception to 19 April 2022. Pooled incidence and risk ratios with 95% confidence intervals (95% CIs) for cardiotoxicity events were calculated. Results A total of 37 studies covering 38 trials, including 14,342 patients, were identified. The pooled risk ratios of incidence of any cardiac AEs were 1.944 [95% CI 0.8–4.725] (Single ICI versus chemotherapy), 1.677 [95% CI 1.065–2.64] (Single ICI plus chemotherapy versus chemotherapy), and 0.478 [95% CI 0.127–1.798] (Single ICI versus Dual ICI). The incidence of myocarditis and arrhythmia were 0.003[95%CI 0.002–0.006] and 0.014[95%CI 0–0.037], respectively. Conclusion Single ICI did not increase the risk of cardiotoxicity compared with chemotherapy, and single ICI plus chemotherapy increased the risk of cardiotoxicity by 67% compared with chemotherapy alone. Combination immunotherapy did not increase the risk of cardiotoxicity compared with single ICI." @default.
• W4309387934 created "2022-11-26" @default.
• W4309387934 creator A5013297039 @default.
• W4309387934 creator A5023028859 @default.
• W4309387934 creator A5048637587 @default.
• W4309387934 creator A5079927352 @default.
• W4309387934 date "2022-11-19" @default.
• W4309387934 modified "2023-10-01" @default.
• W4309387934 title "Immune checkpoint inhibitor-related adverse cardiac events in patients with lung cancer: a systematic review and meta-analysis" @default.
• W4309387934 cites W1883643540 @default.
• W4309387934 cites W1990405213 @default.
• W4309387934 cites W2098923148 @default.
• W4309387934 cites W2104347254 @default.
• W4309387934 cites W2119340816 @default.
• W4309387934 cites W2125435699 @default.
• W4309387934 cites W2130852062 @default.
• W4309387934 cites W2150058408 @default.
• W4309387934 cites W2156098321 @default.
• W4309387934 cites W2198093519 @default.
• W4309387934 cites W2312569965 @default.
• W4309387934 cites W2418354692 @default.
• W4309387934 cites W2480201404 @default.
• W4309387934 cites W2529904548 @default.
• W4309387934 cites W2537295025 @default.
• W4309387934 cites W2547133566 @default.
• W4309387934 cites W2560367415 @default.
• W4309387934 cites W2560560709 @default.
• W4309387934 cites W2572174216 @default.
• W4309387934 cites W2587327379 @default.
• W4309387934 cites W2588681363 @default.
• W4309387934 cites W2625395613 @default.
• W4309387934 cites W2635951006 @default.
• W4309387934 cites W2753065806 @default.
• W4309387934 cites W2769229435 @default.
• W4309387934 cites W2789315292 @default.
• W4309387934 cites W2791265590 @default.
• W4309387934 cites W2791290180 @default.
• W4309387934 cites W2791483720 @default.
• W4309387934 cites W2793167197 @default.
• W4309387934 cites W2805354595 @default.
• W4309387934 cites W2893602866 @default.
• W4309387934 cites W2893960509 @default.
• W4309387934 cites W2901191795 @default.
• W4309387934 cites W2919091706 @default.
• W4309387934 cites W2925446385 @default.
• W4309387934 cites W2943781197 @default.
• W4309387934 cites W2946386783 @default.
• W4309387934 cites W2977392388 @default.
• W4309387934 cites W2980670340 @default.
• W4309387934 cites W2990621342 @default.
• W4309387934 cites W2991792334 @default.
• W4309387934 cites W3008374819 @default.
• W4309387934 cites W3017322331 @default.
• W4309387934 cites W3072782591 @default.
• W4309387934 cites W3080803693 @default.
• W4309387934 cites W3084285067 @default.
• W4309387934 cites W3084355783 @default.
• W4309387934 cites W3092159910 @default.
• W4309387934 cites W3092727194 @default.
• W4309387934 cites W3095297211 @default.
• W4309387934 cites W3097144251 @default.
• W4309387934 cites W3117633542 @default.
• W4309387934 cites W3124587416 @default.
• W4309387934 cites W3125795216 @default.
• W4309387934 cites W3128646645 @default.
• W4309387934 cites W3129022890 @default.
• W4309387934 cites W3133832379 @default.
• W4309387934 cites W3134997217 @default.
• W4309387934 cites W3139213826 @default.
• W4309387934 cites W3152878368 @default.
• W4309387934 cites W3163414580 @default.
• W4309387934 cites W3181034934 @default.
• W4309387934 cites W3196318196 @default.
• W4309387934 cites W3203613457 @default.
• W4309387934 cites W4206362366 @default.
• W4309387934 cites W4211082352 @default.
• W4309387934 doi "https://doi.org/10.1186/s12935-022-02760-2" @default.
• W4309387934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36402980" @default.
• W4309387934 hasPublicationYear "2022" @default.
• W4309387934 type Work @default.
• W4309387934 citedByCount "3" @default.
• W4309387934 countsByYear W43093879342022 @default.
• W4309387934 countsByYear W43093879342023 @default.
• W4309387934 crossrefType "journal-article" @default.
• W4309387934 hasAuthorship W4309387934A5013297039 @default.
• W4309387934 hasAuthorship W4309387934A5023028859 @default.
• W4309387934 hasAuthorship W4309387934A5048637587 @default.
• W4309387934 hasAuthorship W4309387934A5079927352 @default.
• W4309387934 hasBestOaLocation W43093879341 @default.
• W4309387934 hasConcept C120665830 @default.
• W4309387934 hasConcept C121332964 @default.
• W4309387934 hasConcept C121608353 @default.
• W4309387934 hasConcept C126322002 @default.
• W4309387934 hasConcept C143998085 @default.
• W4309387934 hasConcept C164705383 @default.
• W4309387934 hasConcept C197934379 @default.
• W4309387934 hasConcept C2776256026 @default.
• W4309387934 hasConcept C2776694085 @default.
• W4309387934 hasConcept C2778233292 @default.
• W4309387934 hasConcept C2780875844 @default.

• next