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- W4309449989 endingPage "8023" @default.
- W4309449989 startingPage "8023" @default.
- W4309449989 abstract "The roles of medicinal plants or their purified bioactive compounds have attracted attention in the field of health sciences due to their low toxicity and minimal side effects. Baicalein is an active polyphenolic compound, isolated from Scutellaria baicalensis, and plays a significant role in the management of different diseases. Epidemiologic studies have proven that there is an inverse association between baicalein consumption and disease severity. Baicalein is known to display anticancer activity through the inhibition of inflammation and cell proliferation. Additionally, the anticancer potential of baicalein is chiefly mediated through the modulation of various cell-signaling pathways, such as the induction of apoptosis, autophagy, cell cycle arrest, inhibition of angiogenesis, signal transducer and activator of transcription 3, and PI3K/Akt pathways, as well as the regulation of other molecular targets. Therefore, the current review aimed to explore the role of baicalein in different types of cancer along with mechanisms of action. Besides this, the synergistic effects with other anti-cancerous drugs and the nano-formulation based delivery of baicalein have also been discussed." @default.
- W4309449989 created "2022-11-28" @default.
- W4309449989 creator A5019957221 @default.
- W4309449989 creator A5053866227 @default.
- W4309449989 creator A5062611579 @default.
- W4309449989 creator A5082284202 @default.
- W4309449989 creator A5084401624 @default.
- W4309449989 creator A5087747901 @default.
- W4309449989 date "2022-11-18" @default.
- W4309449989 modified "2023-10-01" @default.
- W4309449989 title "The Multifaceted Role of Baicalein in Cancer Management through Modulation of Cell Signalling Pathways" @default.
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