Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309461291> ?p ?o ?g. }
- W4309461291 abstract "Thyroid hormones (THs) play a major role regulating energy balance and brown adipose tissue (BAT) thermogenesis, as well as body temperature, as shown in hyperthyroid patients. However, the current landscape of preclinical thyroid hormone models is complex. For example, while rats become catabolic after TH administration, mice gain weight; so, these differences in species need to be analyzed in detail and specially whether temperature could be a factor. Here, we aimed to investigate the effect of environmental temperature on those actions. Rats were subcutaneously treated with L-thyroxine (T4) or stereotaxically within the ventromedial nucleus of the hypothalamus (VMH) with triiodothyronine (T3) and housed at 23°C, 4°C or 30°C; energy balance, BAT thermogenesis and AMP-activated protein kinase (AMPK) in the VMH were analyzed. Our data showed that the effect of both systemic T4 of central T3 on energy balance and BAT thermogenesis was dependent upon environmental temperature. This evidence is of interest in the design of experimental settings highlighting the species-specific metabolic actions of THs, and in understanding its physiological role in the adaptation to temperature." @default.
- W4309461291 created "2022-11-28" @default.
- W4309461291 creator A5005362009 @default.
- W4309461291 creator A5016276016 @default.
- W4309461291 creator A5020982137 @default.
- W4309461291 creator A5028809564 @default.
- W4309461291 creator A5044168126 @default.
- W4309461291 creator A5056048931 @default.
- W4309461291 creator A5060565425 @default.
- W4309461291 creator A5077712842 @default.
- W4309461291 creator A5085134513 @default.
- W4309461291 creator A5090522575 @default.
- W4309461291 date "2022-11-18" @default.
- W4309461291 modified "2023-10-03" @default.
- W4309461291 title "Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis" @default.
- W4309461291 cites W1484240941 @default.
- W4309461291 cites W1604211023 @default.
- W4309461291 cites W1867360090 @default.
- W4309461291 cites W1966415237 @default.
- W4309461291 cites W1966824338 @default.
- W4309461291 cites W1967608294 @default.
- W4309461291 cites W1972959173 @default.
- W4309461291 cites W1997371910 @default.
- W4309461291 cites W1999310337 @default.
- W4309461291 cites W2007558589 @default.
- W4309461291 cites W2011347812 @default.
- W4309461291 cites W2028347970 @default.
- W4309461291 cites W2057235310 @default.
- W4309461291 cites W2084494302 @default.
- W4309461291 cites W2085412379 @default.
- W4309461291 cites W2088498331 @default.
- W4309461291 cites W2107511244 @default.
- W4309461291 cites W2109873281 @default.
- W4309461291 cites W2124690759 @default.
- W4309461291 cites W2125618313 @default.
- W4309461291 cites W2132358997 @default.
- W4309461291 cites W2138100786 @default.
- W4309461291 cites W2159444491 @default.
- W4309461291 cites W2160033930 @default.
- W4309461291 cites W2164577763 @default.
- W4309461291 cites W2169714338 @default.
- W4309461291 cites W2256418959 @default.
- W4309461291 cites W2281545511 @default.
- W4309461291 cites W2402553346 @default.
- W4309461291 cites W2515318044 @default.
- W4309461291 cites W2518904228 @default.
- W4309461291 cites W2558408965 @default.
- W4309461291 cites W2727251727 @default.
- W4309461291 cites W2785340274 @default.
- W4309461291 cites W2946728233 @default.
- W4309461291 cites W2949177955 @default.
- W4309461291 cites W2971711445 @default.
- W4309461291 cites W3011615297 @default.
- W4309461291 cites W3127200335 @default.
- W4309461291 cites W3131320288 @default.
- W4309461291 cites W3183709545 @default.
- W4309461291 cites W3194196501 @default.
- W4309461291 cites W3196933545 @default.
- W4309461291 cites W3204730538 @default.
- W4309461291 cites W3207377400 @default.
- W4309461291 cites W3215322531 @default.
- W4309461291 cites W4200490813 @default.
- W4309461291 cites W4212809095 @default.
- W4309461291 cites W4280495204 @default.
- W4309461291 cites W84717660 @default.
- W4309461291 doi "https://doi.org/10.3389/fphys.2022.1017381" @default.
- W4309461291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36467699" @default.
- W4309461291 hasPublicationYear "2022" @default.
- W4309461291 type Work @default.
- W4309461291 citedByCount "3" @default.
- W4309461291 countsByYear W43094612912023 @default.
- W4309461291 crossrefType "journal-article" @default.
- W4309461291 hasAuthorship W4309461291A5005362009 @default.
- W4309461291 hasAuthorship W4309461291A5016276016 @default.
- W4309461291 hasAuthorship W4309461291A5020982137 @default.
- W4309461291 hasAuthorship W4309461291A5028809564 @default.
- W4309461291 hasAuthorship W4309461291A5044168126 @default.
- W4309461291 hasAuthorship W4309461291A5056048931 @default.
- W4309461291 hasAuthorship W4309461291A5060565425 @default.
- W4309461291 hasAuthorship W4309461291A5077712842 @default.
- W4309461291 hasAuthorship W4309461291A5085134513 @default.
- W4309461291 hasAuthorship W4309461291A5090522575 @default.
- W4309461291 hasBestOaLocation W43094612911 @default.
- W4309461291 hasConcept C100564792 @default.
- W4309461291 hasConcept C126322002 @default.
- W4309461291 hasConcept C134018914 @default.
- W4309461291 hasConcept C151279926 @default.
- W4309461291 hasConcept C171089720 @default.
- W4309461291 hasConcept C184235292 @default.
- W4309461291 hasConcept C2777003273 @default.
- W4309461291 hasConcept C2778288131 @default.
- W4309461291 hasConcept C2779571634 @default.
- W4309461291 hasConcept C2780124434 @default.
- W4309461291 hasConcept C2780642333 @default.
- W4309461291 hasConcept C526584372 @default.
- W4309461291 hasConcept C71315377 @default.
- W4309461291 hasConcept C71924100 @default.
- W4309461291 hasConcept C86803240 @default.
- W4309461291 hasConcept C95444343 @default.
- W4309461291 hasConcept C97029542 @default.