Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309461502> ?p ?o ?g. }
- W4309461502 endingPage "1421" @default.
- W4309461502 startingPage "1421" @default.
- W4309461502 abstract "Background. Research studies indicate that immunization with protein extracts of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, prevents the appearance of tumors in 60% of mice injected with the murine lung carcinoma tumor line. The molecular basis of this process is unknown, although the presence of specific antigens in tumor cells and on the surface of T. cruzi suggests an antiparasitic immune response, with an effective cross-reaction against cancer cells, hence the importance to identify the antigens involved and determine their potential as target cells in anticancer therapy. Aim. This study aimed to determine the presence of antigenic proteins of T. cruzi shared with acute lymphoblastic leukemia and neuroblastoma cells. Material and methods. To achieve this, polyclonal antibodies against T. cruzi were developed in rabbits, and reactivity was determined with protein extracts of acute lymphoblastic leukemia cells and neuroblastoma. The immunodetection of five different strains of T. cruzi against anti-T. cruzi polyclonal antibodies was also performed. Conclusion. The study allows the knowledge of the immunological interactions between cancer and parasites to be expanded and, therefore, contributes to the design of more and better projects that improve the therapeutic strategies applied in oncology." @default.
- W4309461502 created "2022-11-28" @default.
- W4309461502 creator A5016310552 @default.
- W4309461502 creator A5020530055 @default.
- W4309461502 creator A5025129827 @default.
- W4309461502 creator A5032179283 @default.
- W4309461502 creator A5057381386 @default.
- W4309461502 creator A5064890499 @default.
- W4309461502 date "2022-11-17" @default.
- W4309461502 modified "2023-09-30" @default.
- W4309461502 title "Trypanosoma cruzi Antigenic Proteins Shared with Acute Lymphoblastic Leukemia and Neuroblastoma" @default.
- W4309461502 cites W1757407923 @default.
- W4309461502 cites W1831631893 @default.
- W4309461502 cites W1879221139 @default.
- W4309461502 cites W1965017712 @default.
- W4309461502 cites W2003280335 @default.
- W4309461502 cites W2003814325 @default.
- W4309461502 cites W2007757226 @default.
- W4309461502 cites W2041451382 @default.
- W4309461502 cites W2084239202 @default.
- W4309461502 cites W2091245382 @default.
- W4309461502 cites W2095847059 @default.
- W4309461502 cites W2096288074 @default.
- W4309461502 cites W2107085127 @default.
- W4309461502 cites W2118395707 @default.
- W4309461502 cites W2128066544 @default.
- W4309461502 cites W2130925781 @default.
- W4309461502 cites W2168493692 @default.
- W4309461502 cites W2264594755 @default.
- W4309461502 cites W2519014474 @default.
- W4309461502 cites W2558888782 @default.
- W4309461502 cites W2587171828 @default.
- W4309461502 cites W2734685737 @default.
- W4309461502 cites W2767897165 @default.
- W4309461502 cites W2893675802 @default.
- W4309461502 cites W2986423934 @default.
- W4309461502 cites W3021578663 @default.
- W4309461502 cites W3192105169 @default.
- W4309461502 cites W4211046582 @default.
- W4309461502 cites W4233108259 @default.
- W4309461502 cites W4234558499 @default.
- W4309461502 cites W4246440810 @default.
- W4309461502 cites W4254055155 @default.
- W4309461502 cites W93337180 @default.
- W4309461502 doi "https://doi.org/10.3390/ph15111421" @default.
- W4309461502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36422551" @default.
- W4309461502 hasPublicationYear "2022" @default.
- W4309461502 type Work @default.
- W4309461502 citedByCount "0" @default.
- W4309461502 crossrefType "journal-article" @default.
- W4309461502 hasAuthorship W4309461502A5016310552 @default.
- W4309461502 hasAuthorship W4309461502A5020530055 @default.
- W4309461502 hasAuthorship W4309461502A5025129827 @default.
- W4309461502 hasAuthorship W4309461502A5032179283 @default.
- W4309461502 hasAuthorship W4309461502A5057381386 @default.
- W4309461502 hasAuthorship W4309461502A5064890499 @default.
- W4309461502 hasBestOaLocation W43094615021 @default.
- W4309461502 hasConcept C112418997 @default.
- W4309461502 hasConcept C121608353 @default.
- W4309461502 hasConcept C136764020 @default.
- W4309461502 hasConcept C147483822 @default.
- W4309461502 hasConcept C159047783 @default.
- W4309461502 hasConcept C159654299 @default.
- W4309461502 hasConcept C203014093 @default.
- W4309461502 hasConcept C2776715637 @default.
- W4309461502 hasConcept C2777625466 @default.
- W4309461502 hasConcept C2778461978 @default.
- W4309461502 hasConcept C2780635560 @default.
- W4309461502 hasConcept C41008148 @default.
- W4309461502 hasConcept C502942594 @default.
- W4309461502 hasConcept C54355233 @default.
- W4309461502 hasConcept C71924100 @default.
- W4309461502 hasConcept C71928629 @default.
- W4309461502 hasConcept C81885089 @default.
- W4309461502 hasConcept C86803240 @default.
- W4309461502 hasConcept C8891405 @default.
- W4309461502 hasConcept C956191 @default.
- W4309461502 hasConceptScore W4309461502C112418997 @default.
- W4309461502 hasConceptScore W4309461502C121608353 @default.
- W4309461502 hasConceptScore W4309461502C136764020 @default.
- W4309461502 hasConceptScore W4309461502C147483822 @default.
- W4309461502 hasConceptScore W4309461502C159047783 @default.
- W4309461502 hasConceptScore W4309461502C159654299 @default.
- W4309461502 hasConceptScore W4309461502C203014093 @default.
- W4309461502 hasConceptScore W4309461502C2776715637 @default.
- W4309461502 hasConceptScore W4309461502C2777625466 @default.
- W4309461502 hasConceptScore W4309461502C2778461978 @default.
- W4309461502 hasConceptScore W4309461502C2780635560 @default.
- W4309461502 hasConceptScore W4309461502C41008148 @default.
- W4309461502 hasConceptScore W4309461502C502942594 @default.
- W4309461502 hasConceptScore W4309461502C54355233 @default.
- W4309461502 hasConceptScore W4309461502C71924100 @default.
- W4309461502 hasConceptScore W4309461502C71928629 @default.
- W4309461502 hasConceptScore W4309461502C81885089 @default.
- W4309461502 hasConceptScore W4309461502C86803240 @default.
- W4309461502 hasConceptScore W4309461502C8891405 @default.
- W4309461502 hasConceptScore W4309461502C956191 @default.
- W4309461502 hasIssue "11" @default.