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- W4309476422 abstract "Myosin binding protein C3 (MYBPC3) is a thick filament contractile protein that interacts with myosin, titin and actin and regulates cardiac muscle contraction. Genetic variations in the MYBPC3 gene are known causal factors for cardiomyopathy and heart failure. Previously, we identified a recurrent MYBPC3 deletion (25 base pairs) among South Asians associated with cardiomyopathy and heart failure. Here, we generated an induced pluripotent stem cell (iPSC) line using peripheral blood mononuclear cells (PBMC) from an Indian harboring MYBPC3 deletion. This iPSC line displayed embryonic stem cell morphology, expressed pluripotency markers, differentiated into three germ layers and exhibited normal karyotype." @default.
- W4309476422 created "2022-11-28" @default.
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- W4309476422 date "2022-12-01" @default.
- W4309476422 modified "2023-10-15" @default.
- W4309476422 title "Generation of a new human induced pluripotent stem cell (hiPSC) line from a South Asian Indian with a MYBPC3Δ variant" @default.
- W4309476422 cites W2098450085 @default.
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- W4309476422 doi "https://doi.org/10.1016/j.scr.2022.102978" @default.
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