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- W4309481819 endingPage "122421" @default.
- W4309481819 startingPage "122421" @default.
- W4309481819 abstract "The unprecedented outbreak of severe acute respiratory syndrome-2 (SARS-CoV-2) worldwide has rendered it one of the most notorious pandemics ever documented in human history. As of November 2022, nearly 626 million cases of infection and over 6.6 million deaths have been reported globally. The scientific community has made significant progress in therapeutics and prevention for the management of coronavirus disease (COVID-19), including the development of vaccines and antiviral agents such as monoclonal antibodies and antiviral drugs. Although many advancements and a plethora of positive results have been obtained and global restrictions are being uplifted, obstacles in efficiently delivering these therapies, such as their rapid clearance, suboptimal biodistribution, and toxicity to organs, have yet to be addressed. To address these drawbacks, researchers have attempted applying nanotechnology-based formulations. Here, we summarized the recent data about COVID-19, its emergence, pathophysiology and life cycle, diagnosis, and currently-available medications. Subsequently, we discussed the progress in lipid nanocarriers, such as liposomes in infection detection and control. This review provides critical insights into the design of the latest liposomal-based formulations for tackling the barriers to detecting, preventing, and treating SARS-CoV-2." @default.
- W4309481819 created "2022-11-28" @default.
- W4309481819 creator A5014140512 @default.
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- W4309481819 date "2023-01-01" @default.
- W4309481819 modified "2023-09-25" @default.
- W4309481819 title "Recent updates on liposomal formulations for detection, prevention and treatment of coronavirus disease (COVID-19)" @default.
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- W4309481819 doi "https://doi.org/10.1016/j.ijpharm.2022.122421" @default.
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- W4309481819 hasPublicationYear "2023" @default.
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