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- W4309484414 endingPage "111707" @default.
- W4309484414 startingPage "111707" @default.
- W4309484414 abstract "This investigation aims to obtain a thermosensitive platform useful for specific nanomedicine applications through the addition of suitable salts. An aqueous mixture consisting of the copolymer Pluronic F127 and sodium carboxymethyl-cellulose, in a ratio of 20/4 by weight, in the presence of different concentrations of Na2SO4, NaCl, and NaSCN, was investigated using the visual inversion tube approach to estimate a phase map, and then characterized through rheological measurements. The formation of a cubic liquid crystalline phase at temperatures higher than 37 °C was suggested in all systems. The complex viscosity, decreases in the presence of salts in the order Na2SO4 > NaCl > NaSCN with more marked effect for lower concentrations. Salt addition allows to tune the crowding effect of NaCMC. For the polymer mixture and for a sample containing NaCl, 1H NMR self-diffusion experiments display a non-mono-exponential decay of the echo signals of Pluronic F127, caused by the polydispersity of commercial Pluronic F127. The rheological properties along with the diffusion behaviour of the liquid crystal micelles suggest that a sample containing NaCl 0.07 mol/kg, with a sol-hard gel transition temperature around 35 °C, close to that of the body, may be a suitable and biocompatible thermosensitive platform to administer both hydrophobic and hydrophilic drugs such as antibiotics, anticancer drugs or growing factors. Synopsis: A simple thermoresponsive platform for drug delivery: Pluronic F127, NaCMC and NaCl." @default.
- W4309484414 created "2022-11-28" @default.
- W4309484414 creator A5015967362 @default.
- W4309484414 creator A5019146658 @default.
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- W4309484414 creator A5041316797 @default.
- W4309484414 creator A5047185208 @default.
- W4309484414 creator A5089656590 @default.
- W4309484414 date "2022-12-01" @default.
- W4309484414 modified "2023-10-16" @default.
- W4309484414 title "Effect of electrolytes on the sol–gel phase transitions in a Pluronic F127/carboxymethyl cellulose aqueous system: Phase map, rheology and NMR self-diffusion study" @default.
- W4309484414 cites W1535815157 @default.
- W4309484414 cites W1605936672 @default.
- W4309484414 cites W1966345384 @default.
- W4309484414 cites W1967052201 @default.
- W4309484414 cites W1967985930 @default.
- W4309484414 cites W1968768130 @default.
- W4309484414 cites W1968844151 @default.
- W4309484414 cites W1969898359 @default.
- W4309484414 cites W1970157213 @default.
- W4309484414 cites W1970631860 @default.
- W4309484414 cites W1972414508 @default.
- W4309484414 cites W1973228870 @default.
- W4309484414 cites W1978504668 @default.
- W4309484414 cites W1980750889 @default.
- W4309484414 cites W1980797067 @default.
- W4309484414 cites W1981082070 @default.
- W4309484414 cites W1983141227 @default.
- W4309484414 cites W1983517265 @default.
- W4309484414 cites W1984498082 @default.
- W4309484414 cites W1984762264 @default.
- W4309484414 cites W1986200730 @default.
- W4309484414 cites W1988718154 @default.
- W4309484414 cites W1989682611 @default.
- W4309484414 cites W1990568240 @default.
- W4309484414 cites W1992515211 @default.
- W4309484414 cites W1996262004 @default.
- W4309484414 cites W2001861985 @default.
- W4309484414 cites W2002475066 @default.
- W4309484414 cites W2004468488 @default.
- W4309484414 cites W2009288962 @default.
- W4309484414 cites W2012434595 @default.
- W4309484414 cites W2012588842 @default.
- W4309484414 cites W2016134531 @default.
- W4309484414 cites W2021581216 @default.
- W4309484414 cites W2022020757 @default.
- W4309484414 cites W2022116094 @default.
- W4309484414 cites W2023403048 @default.
- W4309484414 cites W2026625310 @default.
- W4309484414 cites W2032252306 @default.
- W4309484414 cites W2032334473 @default.
- W4309484414 cites W2032604486 @default.
- W4309484414 cites W2034394998 @default.
- W4309484414 cites W2034623660 @default.
- W4309484414 cites W2034915133 @default.
- W4309484414 cites W2037476129 @default.
- W4309484414 cites W2038823703 @default.
- W4309484414 cites W2040426941 @default.
- W4309484414 cites W2053116776 @default.
- W4309484414 cites W2055029992 @default.
- W4309484414 cites W2055409818 @default.
- W4309484414 cites W2059472747 @default.
- W4309484414 cites W2060875402 @default.
- W4309484414 cites W2062026088 @default.
- W4309484414 cites W2065348807 @default.
- W4309484414 cites W2070442888 @default.
- W4309484414 cites W2073319355 @default.
- W4309484414 cites W2073461871 @default.
- W4309484414 cites W2075366183 @default.
- W4309484414 cites W2075558589 @default.
- W4309484414 cites W2076305646 @default.
- W4309484414 cites W2077474285 @default.
- W4309484414 cites W2077502813 @default.
- W4309484414 cites W2078532137 @default.
- W4309484414 cites W2082308498 @default.
- W4309484414 cites W2090610633 @default.
- W4309484414 cites W2093045117 @default.
- W4309484414 cites W2095123159 @default.
- W4309484414 cites W2113282146 @default.
- W4309484414 cites W2132255468 @default.
- W4309484414 cites W2315158026 @default.
- W4309484414 cites W2315772424 @default.
- W4309484414 cites W2316545586 @default.
- W4309484414 cites W2327513996 @default.
- W4309484414 cites W2328714035 @default.
- W4309484414 cites W2460602060 @default.
- W4309484414 cites W2562674550 @default.
- W4309484414 cites W2564948154 @default.
- W4309484414 cites W2573157670 @default.
- W4309484414 cites W2573798310 @default.
- W4309484414 cites W2591444020 @default.
- W4309484414 cites W2619664880 @default.
- W4309484414 cites W2733544289 @default.
- W4309484414 cites W2750065394 @default.
- W4309484414 cites W2754128589 @default.
- W4309484414 cites W2783751372 @default.
- W4309484414 cites W2787930959 @default.