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- W4309486265 abstract "Dielectrophoresis (DEP), different from electrophoresis, is the motion of a dielectric particle in a non-uniform electric field. Recall that a dielectric particle can be polarized by externally applied electric field and form a dipole, i.e., one side of the particle facing the negative electrode has positive charge and the other side of the particle facing the positive electrode has negative charge. If the dielectric particle is suspended in an electrolyte solution, the charged ions in the solution will redistribute near the interface of the particle and the liquid solution under the influence the applied electric field and the electric field of the induced dipole of the dielectric particle. Such charge redistribution depends on the polarizability of the dielectric particle and the surrounding liquid medium. The difference between the charge on the liquid side and the induced charge in the particle is the net charge on each side of the particle, determining the strength of the induced dipole moment, and consequently, the net electric force on the particle. This chapter first presents the basic physics of dielectrophoresis. Then separation of micron-sized particles and cells by size based on DC-DEP is reviewed. Finally, a recently developed novel method of non-uniform electric field produced by using asymmetric orifices on sidewalls of microchannel is introduced. Among its many advantages, this method enables DEP separation of nano-particles with a size difference as small as 10 nm." @default.
- W4309486265 created "2022-11-28" @default.
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- W4309486265 date "2022-11-19" @default.
- W4309486265 modified "2023-09-28" @default.
- W4309486265 title "DC-Dielectrophoresis in Microfluidic Chips" @default.
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- W4309486265 doi "https://doi.org/10.1007/978-3-031-16131-5_3" @default.
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