FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309496720> ?p ?o ?g. }

• W4309496720 endingPage "429" @default.
• W4309496720 startingPage "417" @default.
• W4309496720 abstract "Germline pathogenic variants (GPVs) in the cancer predisposition genes BRCA1 , BRCA2 , MLH1 , MSH2 , MSH6 , BRIP1 , PALB2 , RAD51D and RAD51C are identified in approximately 15% of patients with ovarian cancer (OC). While there are clear guidelines around clinical management of cancer risk in patients with GPV in BRCA1 , BRCA2 , MLH1 , MSH2 and MSH6 , there are few guidelines on how to manage the more moderate OC risk in patients with GPV in BRIP1 , PALB2 , RAD51D and RAD51C , with clinical questions about appropriateness and timing of risk-reducing gynaecological surgery. Furthermore, while recognition of RAD51C and R AD51D as OC predisposition genes has been established for several years, an association with breast cancer (BC) has only more recently been described and clinical management of this risk has been unclear. With expansion of genetic testing of these genes to all patients with non-mucinous OC, new data on BC risk and improved estimates of OC risk, the UK Cancer Genetics Group and CanGene-CanVar project convened a 2-day meeting to reach a national consensus on clinical management of BRIP1 , PALB2 , RAD51D and RAD51C carriers in clinical practice. In this paper, we present a summary of the processes used to reach and agree on a consensus, as well as the key recommendations from the meeting." @default.
• W4309496720 created "2022-11-28" @default.
• W4309496720 creator A5003969210 @default.
• W4309496720 creator A5014201505 @default.
• W4309496720 creator A5015131657 @default.
• W4309496720 creator A5017338560 @default.
• W4309496720 creator A5018344543 @default.
• W4309496720 creator A5027945638 @default.
• W4309496720 creator A5030797235 @default.
• W4309496720 creator A5036970869 @default.
• W4309496720 creator A5038773254 @default.
• W4309496720 creator A5045748016 @default.
• W4309496720 creator A5048942058 @default.
• W4309496720 creator A5051430280 @default.
• W4309496720 creator A5053665832 @default.
• W4309496720 creator A5064477745 @default.
• W4309496720 creator A5065103918 @default.
• W4309496720 creator A5076117857 @default.
• W4309496720 creator A5077364719 @default.
• W4309496720 creator A5080235431 @default.
• W4309496720 creator A5081503406 @default.
• W4309496720 creator A5082046542 @default.
• W4309496720 creator A5087003938 @default.
• W4309496720 creator A5090380142 @default.
• W4309496720 creator A5091116580 @default.
• W4309496720 creator A5091234611 @default.
• W4309496720 date "2022-11-21" @default.
• W4309496720 modified "2023-09-25" @default.
• W4309496720 title "UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes:<i>RAD51C</i>,<i>RAD51D</i>,<i>BRIP1</i>and<i>PALB2</i>" @default.
• W4309496720 cites W1970801031 @default.
• W4309496720 cites W1994948218 @default.
• W4309496720 cites W2000810147 @default.
• W4309496720 cites W2003947899 @default.
• W4309496720 cites W2005551796 @default.
• W4309496720 cites W2016373832 @default.
• W4309496720 cites W2017265038 @default.
• W4309496720 cites W2056739417 @default.
• W4309496720 cites W2088309719 @default.
• W4309496720 cites W2091707270 @default.
• W4309496720 cites W2108873448 @default.
• W4309496720 cites W2111012335 @default.
• W4309496720 cites W2119913499 @default.
• W4309496720 cites W2126282065 @default.
• W4309496720 cites W2135195813 @default.
• W4309496720 cites W2135525536 @default.
• W4309496720 cites W2165606389 @default.
• W4309496720 cites W2325363292 @default.
• W4309496720 cites W2379130638 @default.
• W4309496720 cites W2393739232 @default.
• W4309496720 cites W2404782822 @default.
• W4309496720 cites W2480199247 @default.
• W4309496720 cites W2491158000 @default.
• W4309496720 cites W2583820111 @default.
• W4309496720 cites W2593064974 @default.
• W4309496720 cites W2594216872 @default.
• W4309496720 cites W2605529594 @default.
• W4309496720 cites W2623464423 @default.
• W4309496720 cites W2752883156 @default.
• W4309496720 cites W2765195665 @default.
• W4309496720 cites W2783173081 @default.
• W4309496720 cites W2788597512 @default.
• W4309496720 cites W2789404207 @default.
• W4309496720 cites W2792027007 @default.
• W4309496720 cites W2795832917 @default.
• W4309496720 cites W2799880001 @default.
• W4309496720 cites W2802834623 @default.
• W4309496720 cites W2841045415 @default.
• W4309496720 cites W2891466292 @default.
• W4309496720 cites W2900372855 @default.
• W4309496720 cites W2911915301 @default.
• W4309496720 cites W2911982720 @default.
• W4309496720 cites W2918982382 @default.
• W4309496720 cites W2922947009 @default.
• W4309496720 cites W2928369482 @default.
• W4309496720 cites W2938370698 @default.
• W4309496720 cites W2940359298 @default.
• W4309496720 cites W2946440976 @default.
• W4309496720 cites W2981476382 @default.
• W4309496720 cites W2989421973 @default.
• W4309496720 cites W3007067759 @default.
• W4309496720 cites W3023158970 @default.
• W4309496720 cites W3034297661 @default.
• W4309496720 cites W3042087634 @default.
• W4309496720 cites W3084090243 @default.
• W4309496720 cites W3084253116 @default.
• W4309496720 cites W3092238754 @default.
• W4309496720 cites W3093053551 @default.
• W4309496720 cites W3100475287 @default.
• W4309496720 cites W3124119591 @default.
• W4309496720 cites W3156178891 @default.
• W4309496720 cites W3157365429 @default.
• W4309496720 cites W3161545725 @default.
• W4309496720 cites W3162348833 @default.
• W4309496720 cites W3162975920 @default.
• W4309496720 cites W3165403504 @default.
• W4309496720 cites W3192614487 @default.
• W4309496720 cites W3198033444 @default.
• W4309496720 cites W3201891960 @default.

• next