Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309551344> ?p ?o ?g. }
- W4309551344 endingPage "43" @default.
- W4309551344 startingPage "33" @default.
- W4309551344 abstract "This study aims to evaluate the antioxidant, antibacterial, and cytotoxicity activity of in vitro-raised callus and in vivo-grown rhizome of the vulnerable medicinal plant Paris polyphylla. The antioxidant activity was assessed by DPPH (1,1-diphenyl-2-picrylhydrazyl) assay, the antibacterial activity by agar-well diffusion assay, and cytotoxicity by MTT (3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide) assay. The highest antioxidant activity was found in the dichloromethane (DCM) fraction of rhizome (IC50 = 197.06 ± 0.635 µg/mL) followed by a crude extract of rhizome (IC50 = 339.60 ± 0.680 µg/mL). The DCM fractions showed a minimum inhibitory concentration of 5 mg/mL and a minimum bactericidal concentration of 7.5 mg/mL against E. coli. Similarly, the methanol fraction had the lowest IC50 of 211.36 ± 0.570 µg/mL against MCF-7 cells and the DCM fraction 235.94 ± 0.720 µg/mL against HeLa cells, both of which showed no deleterious effects on normal epithelial cells. Additionally, the in vitro callus' antioxidant (IC50 = 650.54 ± 0.515 µg/mL), antibacterial (inhibited 60 % of tested bacteria), and cytotoxic activities (IC50 = 548.49 ± 0.580 µg/mL on HeLa cells) were comparable to those of the rhizome, and were reported for the first time in P. polyphylla. These results showed that P. polyphylla rhizome and in vitro-raised callus could be a rich source of natural antioxidants, antimicrobials, and anticancer for therapeutic usage." @default.
- W4309551344 created "2022-11-28" @default.
- W4309551344 creator A5022875165 @default.
- W4309551344 creator A5053458733 @default.
- W4309551344 creator A5067517411 @default.
- W4309551344 creator A5069613478 @default.
- W4309551344 creator A5077476755 @default.
- W4309551344 creator A5088260257 @default.
- W4309551344 date "2023-01-01" @default.
- W4309551344 modified "2023-10-16" @default.
- W4309551344 title "Antioxidant, antibacterial, and cytotoxic effect of in vitro callus and in vivo rhizome of Paris polyphylla Sm" @default.
- W4309551344 cites W107511811 @default.
- W4309551344 cites W1516872401 @default.
- W4309551344 cites W1807346500 @default.
- W4309551344 cites W1859949385 @default.
- W4309551344 cites W1871146198 @default.
- W4309551344 cites W1967423388 @default.
- W4309551344 cites W1970513170 @default.
- W4309551344 cites W1972234366 @default.
- W4309551344 cites W1998783968 @default.
- W4309551344 cites W1999528132 @default.
- W4309551344 cites W2008075659 @default.
- W4309551344 cites W2024556021 @default.
- W4309551344 cites W2028171454 @default.
- W4309551344 cites W2036964020 @default.
- W4309551344 cites W2042327967 @default.
- W4309551344 cites W2044573491 @default.
- W4309551344 cites W2050573215 @default.
- W4309551344 cites W2065930640 @default.
- W4309551344 cites W2067478729 @default.
- W4309551344 cites W2070930626 @default.
- W4309551344 cites W2076652631 @default.
- W4309551344 cites W2091647255 @default.
- W4309551344 cites W2092003667 @default.
- W4309551344 cites W2093745691 @default.
- W4309551344 cites W2096256753 @default.
- W4309551344 cites W2128178072 @default.
- W4309551344 cites W2128196141 @default.
- W4309551344 cites W2128590413 @default.
- W4309551344 cites W2128822546 @default.
- W4309551344 cites W2143587740 @default.
- W4309551344 cites W2148125367 @default.
- W4309551344 cites W2152768283 @default.
- W4309551344 cites W2253291125 @default.
- W4309551344 cites W2256742438 @default.
- W4309551344 cites W2403990901 @default.
- W4309551344 cites W2586172744 @default.
- W4309551344 cites W2737116437 @default.
- W4309551344 cites W2766725615 @default.
- W4309551344 cites W2804175286 @default.
- W4309551344 cites W2804208107 @default.
- W4309551344 cites W2804375757 @default.
- W4309551344 cites W3017807885 @default.
- W4309551344 cites W3024143867 @default.
- W4309551344 cites W3025152985 @default.
- W4309551344 cites W4207041583 @default.
- W4309551344 cites W4213053038 @default.
- W4309551344 cites W4293016942 @default.
- W4309551344 doi "https://doi.org/10.1016/j.procbio.2022.11.005" @default.
- W4309551344 hasPublicationYear "2023" @default.
- W4309551344 type Work @default.
- W4309551344 citedByCount "3" @default.
- W4309551344 countsByYear W43095513442023 @default.
- W4309551344 crossrefType "journal-article" @default.
- W4309551344 hasAuthorship W4309551344A5022875165 @default.
- W4309551344 hasAuthorship W4309551344A5053458733 @default.
- W4309551344 hasAuthorship W4309551344A5067517411 @default.
- W4309551344 hasAuthorship W4309551344A5069613478 @default.
- W4309551344 hasAuthorship W4309551344A5077476755 @default.
- W4309551344 hasAuthorship W4309551344A5088260257 @default.
- W4309551344 hasConcept C109316439 @default.
- W4309551344 hasConcept C134550120 @default.
- W4309551344 hasConcept C150903083 @default.
- W4309551344 hasConcept C176947019 @default.
- W4309551344 hasConcept C185592680 @default.
- W4309551344 hasConcept C202751555 @default.
- W4309551344 hasConcept C207001950 @default.
- W4309551344 hasConcept C2777366897 @default.
- W4309551344 hasConcept C2777752497 @default.
- W4309551344 hasConcept C2778004101 @default.
- W4309551344 hasConcept C2780104969 @default.
- W4309551344 hasConcept C2780783641 @default.
- W4309551344 hasConcept C2781401929 @default.
- W4309551344 hasConcept C523546767 @default.
- W4309551344 hasConcept C54355233 @default.
- W4309551344 hasConcept C55493867 @default.
- W4309551344 hasConcept C556039675 @default.
- W4309551344 hasConcept C59822182 @default.
- W4309551344 hasConcept C71924100 @default.
- W4309551344 hasConcept C86803240 @default.
- W4309551344 hasConcept C89423630 @default.
- W4309551344 hasConcept C9549007 @default.
- W4309551344 hasConceptScore W4309551344C109316439 @default.
- W4309551344 hasConceptScore W4309551344C134550120 @default.
- W4309551344 hasConceptScore W4309551344C150903083 @default.
- W4309551344 hasConceptScore W4309551344C176947019 @default.
- W4309551344 hasConceptScore W4309551344C185592680 @default.
- W4309551344 hasConceptScore W4309551344C202751555 @default.