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- W4309558136 abstract "The goal of the present preliminary study was to assess sexual health in breast cancer survivors (BCS) receiving (aromatase inhibitors) AI with genitourinary syndrome of menopause (GSM). preliminary analysis of an ongoing prospective double-blind randomized controlled trial (RCT) with two parallel arms (fractional CO2 laser vs. Sham laser). Main goal RCT: to report an improvement in sexuality. Primary outcome RCT: Female Sexual Function Index (FSFI). Herein, we present cross-sectional observational descriptive analysis focused on baseline sexual data of female BCS receiving AI with GSM, aimed to better understand the previous sexual life of the participants before any intervention. Baseline assessment: epidemiological variables and sexual interview to assess n° sexual activity/week and sexual history. Vaginal Health Index (VHI) is used to vaginal health assessment. Sexual health is assessed with 19-item Spanish validated FSFI questionnaire (1), which score ≤ 26.55 indicates risk of female sexual dysfunction (FSD). A specific Spanish cut-off of ≤21.7 is also proposed (2). Patients reported a visual analogue scale (VAS) 0-10 about disturbance by their sexual life (clinically significant disturbance = scored >3) and on dyspareunia intensity. We included 83 women until August 2021. On average patients had been diagnosed of BC 4,5 years ago and had received different treatments (98.7% surgery, 74% radiotherapy, 71.9% chemotherapy, 100% hormonal therapy). Sample characteristics are described in Table 1. Sexual activity rate was 60%. Our results showed impairment of sexual desire, arousal, lubrication, orgasm and satisfaction; therefore, dyspareunia was not the only dimension which affects sexuality in BCS. Comparing our findings to previous studies on healthy women (1, 2), FSFI mean score was lower and the rate of sexual dysfunction was greater in BCS. So, BCS receiving AI with GSM are at higher risk of FSD and sexual inactivity, both secondary to dyspareunia or other sexual dimensions impairment as desire, arousal, lubrication, orgasm and satisfaction. We have no disclosures." @default.
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- W4309558136 date "2022-11-01" @default.
- W4309558136 modified "2023-10-16" @default.
- W4309558136 title "Sexual health in breast cancer survivors with genitourinary syndrome of menopause: it is only a dyspareunia issue?" @default.
- W4309558136 doi "https://doi.org/10.1016/j.jsxm.2022.10.135" @default.
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