FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309574825> ?p ?o ?g. }

• W4309574825 endingPage "73" @default.
• W4309574825 startingPage "63" @default.
• W4309574825 abstract "Objective: Differentiated thyroid cancer (DTC) is associated with an excellent prognosis, but patients with distant metastatic DTC have a 10-year disease-specific survival (DSS) of just 50%. The incidence of distant metastatic DTC has steadily increased in the United States since the 1980s. The aim of this study was to examine trends in survival and treatment for patients with distant metastatic DTC. Methods: In this population-based, retrospective cohort study, patients with distant metastatic DTC were identified from the Surveillance, Epidemiology, and End Results-13 cancer registry program. Multivariable logistic and Cox regression analyses were used to examine factors associated with DSS and management. Annual percentage changes in treatment patterns were calculated using log-linear regression. Results: During 1992–2018, 1991 patients (69.7% white, 58.0% female, 47.5% aged ≥65 years) were diagnosed with distant metastatic DTC. Papillary thyroid cancer was the most common histological type (74.5%). While the 10-year DSS for overall DTC increased over time (95.4% for patients diagnosed in 1992–1998, 96.6% in 1999–2008, and 97.3% in 2009–2018; p < 0.01), 10-year DSS for DTC with distant metastases did not change (50.2%, 47.3%, and 52.4%, respectively; p = 0.48). Ten-year DSS rates were reduced for patients aged ≥65 years (28.1%), patients undergoing nonsurgical treatment with external beam radiation therapy and/or systemic therapy (6.0%), and patients undergoing no/unknown treatment (32.8%). On multivariable analysis, oncocytic carcinoma, age 65–79 and ≥80 years, male sex, node-positive disease, larger tumor size, nonsurgical treatment, and no/unknown treatment were associated with increased risk of thyroid cancer death. Between 1992 and 2018, the rate of nonsurgical treatment increased, on average, 1.3% per year (1992–1998: 22.9% vs. 2009–2018: 25.6%; p = 0.03), and the rate of patients receiving no/unknown treatment increased 1.9% per year (1992–1998: 11.3% vs. 2009–2018: 15.6%; p = 0.01). Patients aged 65–79 and ≥80 years were more likely than younger patients to receive nonsurgical management or no/unknown treatment. Conclusion: Patients diagnosed with distant metastatic DTC have experienced no improvement in DSS over the past three decades. An increasing proportion of patients diagnosed with distant metastatic DTC are receiving nonsurgical treatment or no/unknown treatment over time; the proportion was highest among the oldest patients." @default.
• W4309574825 created "2022-11-28" @default.
• W4309574825 creator A5037704614 @default.
• W4309574825 creator A5039439529 @default.
• W4309574825 creator A5052004266 @default.
• W4309574825 creator A5065503487 @default.
• W4309574825 creator A5068456665 @default.
• W4309574825 creator A5085701533 @default.
• W4309574825 creator A5087487250 @default.
• W4309574825 date "2023-01-01" @default.
• W4309574825 modified "2023-09-28" @default.
• W4309574825 title "Disease-Specific Survival Trends for Patients Presenting with Differentiated Thyroid Cancer and Distant Metastases in the United States, 1992–2018" @default.
• W4309574825 cites W1957300002 @default.
• W4309574825 cites W1967792499 @default.
• W4309574825 cites W1995267771 @default.
• W4309574825 cites W1996875551 @default.
• W4309574825 cites W1999324180 @default.
• W4309574825 cites W2020326938 @default.
• W4309574825 cites W2023150149 @default.
• W4309574825 cites W2035908446 @default.
• W4309574825 cites W2040642592 @default.
• W4309574825 cites W2044619726 @default.
• W4309574825 cites W2052806549 @default.
• W4309574825 cites W2098223916 @default.
• W4309574825 cites W2112315183 @default.
• W4309574825 cites W2115643427 @default.
• W4309574825 cites W2116542352 @default.
• W4309574825 cites W2122771444 @default.
• W4309574825 cites W2135468945 @default.
• W4309574825 cites W2145150141 @default.
• W4309574825 cites W2168076926 @default.
• W4309574825 cites W2603577764 @default.
• W4309574825 cites W2614017429 @default.
• W4309574825 cites W2766453484 @default.
• W4309574825 cites W2883578491 @default.
• W4309574825 cites W3131430223 @default.
• W4309574825 cites W3184438309 @default.
• W4309574825 cites W4210326524 @default.
• W4309574825 cites W4220847290 @default.
• W4309574825 cites W80791343 @default.
• W4309574825 doi "https://doi.org/10.1089/thy.2022.0353" @default.
• W4309574825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36413032" @default.
• W4309574825 hasPublicationYear "2023" @default.
• W4309574825 type Work @default.
• W4309574825 citedByCount "5" @default.
• W4309574825 countsByYear W43095748252023 @default.
• W4309574825 crossrefType "journal-article" @default.
• W4309574825 hasAuthorship W4309574825A5037704614 @default.
• W4309574825 hasAuthorship W4309574825A5039439529 @default.
• W4309574825 hasAuthorship W4309574825A5052004266 @default.
• W4309574825 hasAuthorship W4309574825A5065503487 @default.
• W4309574825 hasAuthorship W4309574825A5068456665 @default.
• W4309574825 hasAuthorship W4309574825A5085701533 @default.
• W4309574825 hasAuthorship W4309574825A5087487250 @default.
• W4309574825 hasBestOaLocation W43095748252 @default.
• W4309574825 hasConcept C107130276 @default.
• W4309574825 hasConcept C120665830 @default.
• W4309574825 hasConcept C121332964 @default.
• W4309574825 hasConcept C121608353 @default.
• W4309574825 hasConcept C126322002 @default.
• W4309574825 hasConcept C143998085 @default.
• W4309574825 hasConcept C151956035 @default.
• W4309574825 hasConcept C167135981 @default.
• W4309574825 hasConcept C2778527826 @default.
• W4309574825 hasConcept C2779134260 @default.
• W4309574825 hasConcept C2779391198 @default.
• W4309574825 hasConcept C2779761222 @default.
• W4309574825 hasConcept C2908647359 @default.
• W4309574825 hasConcept C2993294228 @default.
• W4309574825 hasConcept C50382708 @default.
• W4309574825 hasConcept C526584372 @default.
• W4309574825 hasConcept C61511704 @default.
• W4309574825 hasConcept C71924100 @default.
• W4309574825 hasConcept C72563966 @default.
• W4309574825 hasConcept C99454951 @default.
• W4309574825 hasConceptScore W4309574825C107130276 @default.
• W4309574825 hasConceptScore W4309574825C120665830 @default.
• W4309574825 hasConceptScore W4309574825C121332964 @default.
• W4309574825 hasConceptScore W4309574825C121608353 @default.
• W4309574825 hasConceptScore W4309574825C126322002 @default.
• W4309574825 hasConceptScore W4309574825C143998085 @default.
• W4309574825 hasConceptScore W4309574825C151956035 @default.
• W4309574825 hasConceptScore W4309574825C167135981 @default.
• W4309574825 hasConceptScore W4309574825C2778527826 @default.
• W4309574825 hasConceptScore W4309574825C2779134260 @default.
• W4309574825 hasConceptScore W4309574825C2779391198 @default.
• W4309574825 hasConceptScore W4309574825C2779761222 @default.
• W4309574825 hasConceptScore W4309574825C2908647359 @default.
• W4309574825 hasConceptScore W4309574825C2993294228 @default.
• W4309574825 hasConceptScore W4309574825C50382708 @default.
• W4309574825 hasConceptScore W4309574825C526584372 @default.
• W4309574825 hasConceptScore W4309574825C61511704 @default.
• W4309574825 hasConceptScore W4309574825C71924100 @default.
• W4309574825 hasConceptScore W4309574825C72563966 @default.
• W4309574825 hasConceptScore W4309574825C99454951 @default.
• W4309574825 hasIssue "1" @default.
• W4309574825 hasLocation W43095748251 @default.
• W4309574825 hasLocation W43095748252 @default.

• next