FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309643791> ?p ?o ?g. }

• W4309643791 endingPage "e702" @default.
• W4309643791 startingPage "e694" @default.
• W4309643791 abstract "Background and Objectives Previous research has examined the association between cognition and flavonoids: bioactives found in foods, known to possess anti-inflammatory and antioxidant properties. We extend this research by investigating associations of dietary intakes of total flavonols and constituents (kaempferol, quercetin, myricetin, and isorhamnetin) on the change in cognitive performance in global cognition, episodic memory, semantic memory, visuospatial ability, perceptual speed, and working memory. Methods The study was conducted using 961 participants (aged 60–100 years) of the Rush Memory and Aging Project, a prospective cohort of community-dwelling Chicagoans who were followed for an average of 6.9 years. Diet was assessed using a validated semiquantitative food frequency questionnaire. Cognitive performance was assessed annually with a battery of 19 standardized tests. Flavonol intake was analyzed as a continuous variable using linear mixed-effects models. Cognitive domain scores were regressed on baseline calorie-adjusted flavonol variables. Results Higher dietary intakes of total flavonols and flavonol constituents were associated with a slower rate of decline in global cognition and multiple cognitive domains. In continuous models adjusted for age, sex, education, APOE ɛ4 , late-life cognitive activity, physical activity, and smoking, total flavonol intake was associated with slower decline in global cognition β estimate = 0.004 (95% CI 0.001–0.006), episodic memory β = 0.004 (95% CI 0.002–0.006), semantic memory β = 0.003 (95% CI 0.001–0.007), perceptual speed β = 0.003 (95% CI 0.001–0.004), and working memory β = 0.003 (95% CI 0.001–0.005) and marginally associated with visuospatial ability β = 0.001 (95% CI −0.001 to 0.003). Analyses of individual flavonol constituents demonstrated that intakes of kaempferol and quercetin were associated with slower global cognitive decline (β = 0.01 [95% CI 0.006–0.02] and β = 0.004 [95% CI 0.0005–0.007]), respectively. Myricetin and isorhamnetin were not associated with global cognition. Discussion Results suggest that dietary intakes of total flavonols and several flavonol constituents may be associated with slower decline in global cognition and multiple cognitive abilities with older age." @default.
• W4309643791 created "2022-11-28" @default.
• W4309643791 creator A5000765323 @default.
• W4309643791 creator A5022605809 @default.
• W4309643791 creator A5026996448 @default.
• W4309643791 creator A5042824125 @default.
• W4309643791 creator A5048123378 @default.
• W4309643791 creator A5070294274 @default.
• W4309643791 creator A5073612672 @default.
• W4309643791 creator A5075838514 @default.
• W4309643791 creator A5087611125 @default.
• W4309643791 creator A5088390845 @default.
• W4309643791 date "2023-02-14" @default.
• W4309643791 modified "2023-10-03" @default.
• W4309643791 title "Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities" @default.
• W4309643791 cites W1702095876 @default.
• W4309643791 cites W1906706131 @default.
• W4309643791 cites W1931372835 @default.
• W4309643791 cites W1966607391 @default.
• W4309643791 cites W1988667864 @default.
• W4309643791 cites W2033706756 @default.
• W4309643791 cites W2039851764 @default.
• W4309643791 cites W2045651253 @default.
• W4309643791 cites W2071392773 @default.
• W4309643791 cites W2071402888 @default.
• W4309643791 cites W2076340493 @default.
• W4309643791 cites W2085308870 @default.
• W4309643791 cites W2092403723 @default.
• W4309643791 cites W2097835633 @default.
• W4309643791 cites W2099554704 @default.
• W4309643791 cites W2118719415 @default.
• W4309643791 cites W2132297564 @default.
• W4309643791 cites W2134920988 @default.
• W4309643791 cites W2135374418 @default.
• W4309643791 cites W2137903965 @default.
• W4309643791 cites W2139747033 @default.
• W4309643791 cites W2142093641 @default.
• W4309643791 cites W2142806020 @default.
• W4309643791 cites W2145157761 @default.
• W4309643791 cites W2157154718 @default.
• W4309643791 cites W2163805600 @default.
• W4309643791 cites W2168556140 @default.
• W4309643791 cites W2469357084 @default.
• W4309643791 cites W2780998634 @default.
• W4309643791 cites W2809330972 @default.
• W4309643791 cites W2912184659 @default.
• W4309643791 cites W2996359437 @default.
• W4309643791 cites W3003231031 @default.
• W4309643791 cites W3016597126 @default.
• W4309643791 cites W3023652360 @default.
• W4309643791 cites W3033403703 @default.
• W4309643791 cites W3184011372 @default.
• W4309643791 doi "https://doi.org/10.1212/wnl.0000000000201541" @default.
• W4309643791 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36414424" @default.
• W4309643791 hasPublicationYear "2023" @default.
• W4309643791 type Work @default.
• W4309643791 citedByCount "6" @default.
• W4309643791 countsByYear W43096437912023 @default.
• W4309643791 crossrefType "journal-article" @default.
• W4309643791 hasAuthorship W4309643791A5000765323 @default.
• W4309643791 hasAuthorship W4309643791A5022605809 @default.
• W4309643791 hasAuthorship W4309643791A5026996448 @default.
• W4309643791 hasAuthorship W4309643791A5042824125 @default.
• W4309643791 hasAuthorship W4309643791A5048123378 @default.
• W4309643791 hasAuthorship W4309643791A5070294274 @default.
• W4309643791 hasAuthorship W4309643791A5073612672 @default.
• W4309643791 hasAuthorship W4309643791A5075838514 @default.
• W4309643791 hasAuthorship W4309643791A5087611125 @default.
• W4309643791 hasAuthorship W4309643791A5088390845 @default.
• W4309643791 hasBestOaLocation W43096437912 @default.
• W4309643791 hasConcept C118552586 @default.
• W4309643791 hasConcept C126322002 @default.
• W4309643791 hasConcept C15744967 @default.
• W4309643791 hasConcept C169900460 @default.
• W4309643791 hasConcept C185711340 @default.
• W4309643791 hasConcept C197914299 @default.
• W4309643791 hasConcept C21963081 @default.
• W4309643791 hasConcept C2777810353 @default.
• W4309643791 hasConcept C2778004101 @default.
• W4309643791 hasConcept C2779106036 @default.
• W4309643791 hasConcept C2779134260 @default.
• W4309643791 hasConcept C2779483572 @default.
• W4309643791 hasConcept C2780450397 @default.
• W4309643791 hasConcept C2781263971 @default.
• W4309643791 hasConcept C2984863031 @default.
• W4309643791 hasConcept C548259974 @default.
• W4309643791 hasConcept C55493867 @default.
• W4309643791 hasConcept C71924100 @default.
• W4309643791 hasConcept C86803240 @default.
• W4309643791 hasConcept C88576662 @default.
• W4309643791 hasConceptScore W4309643791C118552586 @default.
• W4309643791 hasConceptScore W4309643791C126322002 @default.
• W4309643791 hasConceptScore W4309643791C15744967 @default.
• W4309643791 hasConceptScore W4309643791C169900460 @default.
• W4309643791 hasConceptScore W4309643791C185711340 @default.
• W4309643791 hasConceptScore W4309643791C197914299 @default.
• W4309643791 hasConceptScore W4309643791C21963081 @default.
• W4309643791 hasConceptScore W4309643791C2777810353 @default.

• next