Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309646987> ?p ?o ?g. }
- W4309646987 abstract "Abstract When given a choice, humans and many animals prefer smaller but sooner over larger but later rewards, a tendency referred to as temporal discounting. Alterations in devaluation of future rewards have been reported in a range of maladaptive behaviors and clinical conditions. Although temporal discounting is highly stable over time and testing environments (e.g., laboratory vs. virtual reality), it is partly under contextual control. For example, highly appetitive cues such as erotic images might increase preferences for immediate rewards, although overall evidence remains mixed. Dopaminergic circuit activity and striatal dopamine concentrations are often assumed to drive increases in temporal discounting following appetitive cue-exposure, yet this was never explicitly tested. Here we examined cue-reactivity effects (erotic vs. neutral pictures) on subsequent temporal discounting in a pre-registered within-subjects study in healthy male participants (n=38). Functional magnetic resonance imaging (fMRI) assessed neural cue-reactivity, value-computations and choice-related effects. Preregistered analyses replicated previous findings of value coding in ventromedial prefrontal cortices, striatum and cingulate cortex. Likewise, as hypothesized, lateral prefrontal cortex activity increased during choices of delayed rewards, potentially reflecting cognitive control. As predicted, erotic vs. neutral cue exposure was associated with increased activity in attention and reward circuits. Contrary to our preregistered hypotheses, temporal discounting was largely unaffected by cue exposure. Likewise, cue-reactivity in key areas of the dopaminergic reward circuit (Nacc, VTA) was not significantly associated with changes in behavior. Our results indicate that behavioral effects of erotic cue exposure on temporal discounting might not be as unequivocal as previously thought and raise doubt on the hypothesis of an upregulated dopaminergic ramping mechanism, that might support myopic approach behavior towards immediate rewards." @default.
- W4309646987 created "2022-11-29" @default.
- W4309646987 creator A5030256799 @default.
- W4309646987 creator A5051054354 @default.
- W4309646987 creator A5057548135 @default.
- W4309646987 creator A5061249056 @default.
- W4309646987 creator A5085918875 @default.
- W4309646987 date "2022-11-22" @default.
- W4309646987 modified "2023-09-29" @default.
- W4309646987 title "Appetitive cue exposure increases neural reward responses without modulating temporal discounting" @default.
- W4309646987 cites W1545666838 @default.
- W4309646987 cites W1601100579 @default.
- W4309646987 cites W1762110187 @default.
- W4309646987 cites W1915223221 @default.
- W4309646987 cites W1928928322 @default.
- W4309646987 cites W1969214938 @default.
- W4309646987 cites W1974019673 @default.
- W4309646987 cites W1974852668 @default.
- W4309646987 cites W1975745304 @default.
- W4309646987 cites W1976230103 @default.
- W4309646987 cites W1976261289 @default.
- W4309646987 cites W1977234485 @default.
- W4309646987 cites W1977500242 @default.
- W4309646987 cites W1978246260 @default.
- W4309646987 cites W1981786093 @default.
- W4309646987 cites W1984453610 @default.
- W4309646987 cites W1985109675 @default.
- W4309646987 cites W1992488100 @default.
- W4309646987 cites W1994077204 @default.
- W4309646987 cites W1999387961 @default.
- W4309646987 cites W2005033227 @default.
- W4309646987 cites W2005238835 @default.
- W4309646987 cites W2006096283 @default.
- W4309646987 cites W2008970086 @default.
- W4309646987 cites W2010373764 @default.
- W4309646987 cites W2012856073 @default.
- W4309646987 cites W2020041532 @default.
- W4309646987 cites W2021498238 @default.
- W4309646987 cites W2021586194 @default.
- W4309646987 cites W2032502673 @default.
- W4309646987 cites W2033923862 @default.
- W4309646987 cites W2038601419 @default.
- W4309646987 cites W2042485636 @default.
- W4309646987 cites W2043219190 @default.
- W4309646987 cites W2044958594 @default.
- W4309646987 cites W2061731019 @default.
- W4309646987 cites W2066821961 @default.
- W4309646987 cites W2067309572 @default.
- W4309646987 cites W2068715462 @default.
- W4309646987 cites W2071656990 @default.
- W4309646987 cites W2072500831 @default.
- W4309646987 cites W2082648681 @default.
- W4309646987 cites W2083649502 @default.
- W4309646987 cites W2088511157 @default.
- W4309646987 cites W2088853696 @default.
- W4309646987 cites W2094134651 @default.
- W4309646987 cites W2100327536 @default.
- W4309646987 cites W2102419748 @default.
- W4309646987 cites W2105501219 @default.
- W4309646987 cites W2105765381 @default.
- W4309646987 cites W2113616846 @default.
- W4309646987 cites W2114277272 @default.
- W4309646987 cites W2115095583 @default.
- W4309646987 cites W2115719663 @default.
- W4309646987 cites W2115743154 @default.
- W4309646987 cites W2116683201 @default.
- W4309646987 cites W2120927079 @default.
- W4309646987 cites W2126519515 @default.
- W4309646987 cites W2126840659 @default.
- W4309646987 cites W2131099460 @default.
- W4309646987 cites W2133585257 @default.
- W4309646987 cites W2138669222 @default.
- W4309646987 cites W2142477850 @default.
- W4309646987 cites W2147381727 @default.
- W4309646987 cites W2148534890 @default.
- W4309646987 cites W2149564966 @default.
- W4309646987 cites W2149660786 @default.
- W4309646987 cites W2152838366 @default.
- W4309646987 cites W2156516005 @default.
- W4309646987 cites W2160720739 @default.
- W4309646987 cites W2181691336 @default.
- W4309646987 cites W2203714058 @default.
- W4309646987 cites W2340030450 @default.
- W4309646987 cites W2346247261 @default.
- W4309646987 cites W2410111880 @default.
- W4309646987 cites W2412196334 @default.
- W4309646987 cites W2472306680 @default.
- W4309646987 cites W2473403354 @default.
- W4309646987 cites W2511478361 @default.
- W4309646987 cites W2512455032 @default.
- W4309646987 cites W2528866703 @default.
- W4309646987 cites W2531337854 @default.
- W4309646987 cites W2570743725 @default.
- W4309646987 cites W2577537660 @default.
- W4309646987 cites W2584131968 @default.
- W4309646987 cites W2612950433 @default.
- W4309646987 cites W2618093728 @default.
- W4309646987 cites W2786042772 @default.
- W4309646987 cites W2786198454 @default.
- W4309646987 cites W2791586862 @default.