Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309653315> ?p ?o ?g. }
- W4309653315 abstract "Abstract High-throughput “omics” data, including genomic, transcriptomic, and epigenetic data, have become increasingly produced and have contributed in recent years to the advances in cancer research. In particular, multi-modal omics data get now employed in addition to clinical data to stratify patients according to their clinical outcomes. Despite some recent work on benchmarking multi-modal integration strategies for cancer survival prediction, there is still a need for the standardization of the results of model performances and for the consecutive exploration of the relative performance of statistical and deep learning models. Here, we propose a unique benchmark, SurvBoard, which standardizes several important experimental design choices to enable comparability between cancer survival models that incorporate multi-omics data. By designing several benchmarking scenarios, SurvBoard allows for the comparison of single-cancer models and models trained on pan-cancer data; SurvBoard also makes it possible to investigate the added value of using patient data with missing modalities. Additionally, in this work, we point out several potential pitfalls that might arise during the preprocessing and validation of multi-omics cancer survival models and address them in our benchmark. We compare statistical and deep learning models revealing that statistical models often outperform deep learning models, particularly in terms of model calibration. Finally, we offer a web service that enables quick model evaluation against our benchmark ( https://www.survboard.science/ ). All code and other resources are available on GitHub: https://github.com/BoevaLab/survboard/ ." @default.
- W4309653315 created "2022-11-29" @default.
- W4309653315 creator A5009367310 @default.
- W4309653315 creator A5016524881 @default.
- W4309653315 creator A5023557096 @default.
- W4309653315 creator A5041322538 @default.
- W4309653315 creator A5055447150 @default.
- W4309653315 creator A5074876525 @default.
- W4309653315 date "2022-11-20" @default.
- W4309653315 modified "2023-10-16" @default.
- W4309653315 title "SurvBoard: Standardised Benchmarking for Multi-omics Cancer Survival Models" @default.
- W4309653315 cites W1570622790 @default.
- W4309653315 cites W1631913055 @default.
- W4309653315 cites W1986546598 @default.
- W4309653315 cites W2000703258 @default.
- W4309653315 cites W2030678916 @default.
- W4309653315 cites W2050077513 @default.
- W4309653315 cites W2057197272 @default.
- W4309653315 cites W2073241381 @default.
- W4309653315 cites W2084139018 @default.
- W4309653315 cites W2114843025 @default.
- W4309653315 cites W2115875921 @default.
- W4309653315 cites W2120579447 @default.
- W4309653315 cites W2121906867 @default.
- W4309653315 cites W2149441684 @default.
- W4309653315 cites W2157076315 @default.
- W4309653315 cites W2158485828 @default.
- W4309653315 cites W2159370862 @default.
- W4309653315 cites W2230320310 @default.
- W4309653315 cites W2609862046 @default.
- W4309653315 cites W2789924919 @default.
- W4309653315 cites W2797883881 @default.
- W4309653315 cites W2806953728 @default.
- W4309653315 cites W2891381594 @default.
- W4309653315 cites W2896872272 @default.
- W4309653315 cites W2919831875 @default.
- W4309653315 cites W2954499361 @default.
- W4309653315 cites W2996717911 @default.
- W4309653315 cites W3009545736 @default.
- W4309653315 cites W3028304854 @default.
- W4309653315 cites W3041047318 @default.
- W4309653315 cites W3043242675 @default.
- W4309653315 cites W3111736660 @default.
- W4309653315 cites W3124607975 @default.
- W4309653315 cites W4249295594 @default.
- W4309653315 cites W4281478757 @default.
- W4309653315 cites W4285077411 @default.
- W4309653315 cites W4294541781 @default.
- W4309653315 doi "https://doi.org/10.1101/2022.11.18.517043" @default.
- W4309653315 hasPublicationYear "2022" @default.
- W4309653315 type Work @default.
- W4309653315 citedByCount "0" @default.
- W4309653315 crossrefType "posted-content" @default.
- W4309653315 hasAuthorship W4309653315A5009367310 @default.
- W4309653315 hasAuthorship W4309653315A5016524881 @default.
- W4309653315 hasAuthorship W4309653315A5023557096 @default.
- W4309653315 hasAuthorship W4309653315A5041322538 @default.
- W4309653315 hasAuthorship W4309653315A5055447150 @default.
- W4309653315 hasAuthorship W4309653315A5074876525 @default.
- W4309653315 hasBestOaLocation W43096533151 @default.
- W4309653315 hasConcept C108583219 @default.
- W4309653315 hasConcept C111919701 @default.
- W4309653315 hasConcept C114614502 @default.
- W4309653315 hasConcept C119857082 @default.
- W4309653315 hasConcept C124101348 @default.
- W4309653315 hasConcept C13280743 @default.
- W4309653315 hasConcept C144133560 @default.
- W4309653315 hasConcept C154945302 @default.
- W4309653315 hasConcept C157585117 @default.
- W4309653315 hasConcept C162853370 @default.
- W4309653315 hasConcept C185798385 @default.
- W4309653315 hasConcept C188087704 @default.
- W4309653315 hasConcept C197947376 @default.
- W4309653315 hasConcept C205649164 @default.
- W4309653315 hasConcept C2522767166 @default.
- W4309653315 hasConcept C33923547 @default.
- W4309653315 hasConcept C34736171 @default.
- W4309653315 hasConcept C41008148 @default.
- W4309653315 hasConcept C60644358 @default.
- W4309653315 hasConcept C86251818 @default.
- W4309653315 hasConcept C86803240 @default.
- W4309653315 hasConceptScore W4309653315C108583219 @default.
- W4309653315 hasConceptScore W4309653315C111919701 @default.
- W4309653315 hasConceptScore W4309653315C114614502 @default.
- W4309653315 hasConceptScore W4309653315C119857082 @default.
- W4309653315 hasConceptScore W4309653315C124101348 @default.
- W4309653315 hasConceptScore W4309653315C13280743 @default.
- W4309653315 hasConceptScore W4309653315C144133560 @default.
- W4309653315 hasConceptScore W4309653315C154945302 @default.
- W4309653315 hasConceptScore W4309653315C157585117 @default.
- W4309653315 hasConceptScore W4309653315C162853370 @default.
- W4309653315 hasConceptScore W4309653315C185798385 @default.
- W4309653315 hasConceptScore W4309653315C188087704 @default.
- W4309653315 hasConceptScore W4309653315C197947376 @default.
- W4309653315 hasConceptScore W4309653315C205649164 @default.
- W4309653315 hasConceptScore W4309653315C2522767166 @default.
- W4309653315 hasConceptScore W4309653315C33923547 @default.
- W4309653315 hasConceptScore W4309653315C34736171 @default.
- W4309653315 hasConceptScore W4309653315C41008148 @default.
- W4309653315 hasConceptScore W4309653315C60644358 @default.