FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309660295> ?p ?o ?g. }

• W4309660295 abstract "Background Liver microcirculation dysfunction plays a vital role in the occurrence and development of liver diseases, and thus, there is a clinical need for in vivo, noninvasive, and quantitative evaluation of liver microcirculation. Purpose To evaluate the feasibility of ultrasensitive US microvessel imaging (UMI) in the visualization and quantification of hepatic microvessels in healthy and cirrhotic rats. Materials and Methods In vivo studies were performed to image hepatic microvasculature by means of laparotomy in Sprague-Dawley rats (five cirrhotic and five control rats). In vivo conventional power Doppler US and ex vivo micro-CT were performed for comparison. UMI-based quantifications of perfusion, tortuosity, and integrity of microvessels were compared between the control and cirrhotic groups by using the Wilcoxon test. Spearman correlations between quantification parameters and pathologic fibrosis, perfusion function, and hepatic hypoxia were evaluated. Results UMI helped detect minute vessels below the liver capsule, as compared with conventional power Doppler US and micro-CT. With use of UMI, lower perfusion indicated by vessel density (median, 22% [IQR, 20%–28%] vs 41% [IQR, 37%–46%]; P = .008) and fractional moving blood volume (FMBV) (median, 6.4% [IQR, 4.8%–8.6%] vs 13% [IQR, 12%–14%]; P = .008) and higher tortuosity indicated by the sum of angles metric (SOAM) (median, 3.0 [IQR, 2.9–3.0] vs 2.7 [IQR, 2.6–2.9]; P = .008) were demonstrated in the cirrhotic rat group compared with the control group. Vessel density (r = 0.85, P = .003), FMBV (r = 0.86, P = .002), and median SOAM (r = −0.83, P = .003) showed strong correlations with pathologically derived vessel density labeled with dextran. Vessel density (r = −0.81, P = .005) and median SOAM (r = 0.87, P = .001) also showed strong correlations with hepatic tissue hypoxia. Conclusion Contrast-free ultrasensitive US microvessel imaging provided noninvasive in vivo imaging and quantification of hepatic microvessels in cirrhotic rat liver. © RSNA, 2022 Supplemental material is available for this article. See also the editorial by Fetzer in this issue." @default.
• W4309660295 created "2022-11-29" @default.
• W4309660295 creator A5001557554 @default.
• W4309660295 creator A5029345864 @default.
• W4309660295 creator A5037951010 @default.
• W4309660295 creator A5040269037 @default.
• W4309660295 creator A5046212401 @default.
• W4309660295 creator A5074030191 @default.
• W4309660295 creator A5084449779 @default.
• W4309660295 creator A5090152485 @default.
• W4309660295 date "2023-04-01" @default.
• W4309660295 modified "2023-10-18" @default.
• W4309660295 title "Ultrasensitive US Microvessel Imaging of Hepatic Microcirculation in the Cirrhotic Rat Liver" @default.
• W4309660295 cites W1565953897 @default.
• W4309660295 cites W1974852983 @default.
• W4309660295 cites W1981900811 @default.
• W4309660295 cites W1995848013 @default.
• W4309660295 cites W1995913833 @default.
• W4309660295 cites W1996438825 @default.
• W4309660295 cites W2006526959 @default.
• W4309660295 cites W2009733331 @default.
• W4309660295 cites W2062557346 @default.
• W4309660295 cites W2078036072 @default.
• W4309660295 cites W2089945888 @default.
• W4309660295 cites W2126052291 @default.
• W4309660295 cites W2164689751 @default.
• W4309660295 cites W2347070364 @default.
• W4309660295 cites W2470906679 @default.
• W4309660295 cites W2480790512 @default.
• W4309660295 cites W2512639889 @default.
• W4309660295 cites W2570344710 @default.
• W4309660295 cites W2773813633 @default.
• W4309660295 cites W2800873425 @default.
• W4309660295 cites W2887542134 @default.
• W4309660295 cites W2904680828 @default.
• W4309660295 cites W2909340549 @default.
• W4309660295 cites W2922852595 @default.
• W4309660295 cites W2935958115 @default.
• W4309660295 cites W2938475891 @default.
• W4309660295 cites W2945916124 @default.
• W4309660295 cites W2948523086 @default.
• W4309660295 cites W2972867751 @default.
• W4309660295 cites W3000957625 @default.
• W4309660295 cites W3010121905 @default.
• W4309660295 cites W3016578761 @default.
• W4309660295 cites W3027740287 @default.
• W4309660295 cites W3125874206 @default.
• W4309660295 cites W3132971647 @default.
• W4309660295 doi "https://doi.org/10.1148/radiol.220739" @default.
• W4309660295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36413130" @default.
• W4309660295 hasPublicationYear "2023" @default.
• W4309660295 type Work @default.
• W4309660295 citedByCount "0" @default.
• W4309660295 crossrefType "journal-article" @default.
• W4309660295 hasAuthorship W4309660295A5001557554 @default.
• W4309660295 hasAuthorship W4309660295A5029345864 @default.
• W4309660295 hasAuthorship W4309660295A5037951010 @default.
• W4309660295 hasAuthorship W4309660295A5040269037 @default.
• W4309660295 hasAuthorship W4309660295A5046212401 @default.
• W4309660295 hasAuthorship W4309660295A5074030191 @default.
• W4309660295 hasAuthorship W4309660295A5084449779 @default.
• W4309660295 hasAuthorship W4309660295A5090152485 @default.
• W4309660295 hasConcept C126322002 @default.
• W4309660295 hasConcept C126838900 @default.
• W4309660295 hasConcept C12722491 @default.
• W4309660295 hasConcept C142724271 @default.
• W4309660295 hasConcept C146957229 @default.
• W4309660295 hasConcept C150903083 @default.
• W4309660295 hasConcept C204232928 @default.
• W4309660295 hasConcept C207001950 @default.
• W4309660295 hasConcept C26291073 @default.
• W4309660295 hasConcept C2776436680 @default.
• W4309660295 hasConcept C2777214474 @default.
• W4309660295 hasConcept C2778808290 @default.
• W4309660295 hasConcept C2989005 @default.
• W4309660295 hasConcept C71924100 @default.
• W4309660295 hasConcept C86803240 @default.
• W4309660295 hasConceptScore W4309660295C126322002 @default.
• W4309660295 hasConceptScore W4309660295C126838900 @default.
• W4309660295 hasConceptScore W4309660295C12722491 @default.
• W4309660295 hasConceptScore W4309660295C142724271 @default.
• W4309660295 hasConceptScore W4309660295C146957229 @default.
• W4309660295 hasConceptScore W4309660295C150903083 @default.
• W4309660295 hasConceptScore W4309660295C204232928 @default.
• W4309660295 hasConceptScore W4309660295C207001950 @default.
• W4309660295 hasConceptScore W4309660295C26291073 @default.
• W4309660295 hasConceptScore W4309660295C2776436680 @default.
• W4309660295 hasConceptScore W4309660295C2777214474 @default.
• W4309660295 hasConceptScore W4309660295C2778808290 @default.
• W4309660295 hasConceptScore W4309660295C2989005 @default.
• W4309660295 hasConceptScore W4309660295C71924100 @default.
• W4309660295 hasConceptScore W4309660295C86803240 @default.
• W4309660295 hasFunder F4320321001 @default.
• W4309660295 hasFunder F4320336405 @default.
• W4309660295 hasIssue "1" @default.
• W4309660295 hasLocation W43096602951 @default.
• W4309660295 hasLocation W43096602952 @default.
• W4309660295 hasOpenAccess W4309660295 @default.
• W4309660295 hasPrimaryLocation W43096602951 @default.
• W4309660295 hasRelatedWork W2023637975 @default.

• next