FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309667218> ?p ?o ?g. }

• W4309667218 endingPage "356" @default.
• W4309667218 startingPage "347" @default.
• W4309667218 abstract "Early life adversity (ELA) is a risk factor for early onset morbidities and mortality, a relationship that may be driven in part by immune system dysregulation. One mechanism of dysregulation that has yet to be fully examined in the context of ELA is alterations to immune cell dynamics in response to acute stress. Using a within-person between-group experimental design, we investigated stress-induced changes in immune cell populations, and how these changes may be altered in individuals with a history of ELA. Participants were young adults (N = 34, aged 18–25 years, 53% female, 47% with a history of ELA). Complete immune cell counts were measured at four time-points over a 5-hour window across two sessions (Trier Social Stress Test [TSST] vs. no-stress) separated by a week. Across all participants, total white blood cells increased over time (F(3,84)=38.97, p < .001) with a greater increase in response to the TSST compared to the no-stress condition at 240 minutes post-test (b = 0.43±.19; t(179)=2.22, p = .027). This pattern was mirrored by neutrophil counts. Lymphocyte counts were initially depressed by TSST exposure (b =−205±.67; t(184)=−3.07, p = .002) but recovered above baseline. ELA status was associated with higher stress-induced immune cell counts, a difference likely driven by increases in neutrophils (F(1,22)=4.45, p = .046). Overall, these results indicate differential immune cell dynamics in response to acute stress in individuals with a history of ELA. This points to altered immune system functioning in the context of stress, a finding that may be driving increased morbidity and mortality risk for ELA-exposed individuals." @default.
• W4309667218 created "2022-11-29" @default.
• W4309667218 creator A5009337522 @default.
• W4309667218 creator A5031758996 @default.
• W4309667218 creator A5045323045 @default.
• W4309667218 creator A5047495439 @default.
• W4309667218 creator A5058957631 @default.
• W4309667218 creator A5059900250 @default.
• W4309667218 creator A5083460285 @default.
• W4309667218 creator A5090244949 @default.
• W4309667218 date "2022-01-02" @default.
• W4309667218 modified "2023-09-26" @default.
• W4309667218 title "Immune cell dynamics in response to an acute laboratory stressor: a within-person between-group analysis of the biological impact of early life adversity" @default.
• W4309667218 cites W1193057051 @default.
• W4309667218 cites W1584609572 @default.
• W4309667218 cites W1592968073 @default.
• W4309667218 cites W1930346527 @default.
• W4309667218 cites W1964081088 @default.
• W4309667218 cites W1980957012 @default.
• W4309667218 cites W1981459575 @default.
• W4309667218 cites W1990361157 @default.
• W4309667218 cites W1994025460 @default.
• W4309667218 cites W1997110253 @default.
• W4309667218 cites W2016658076 @default.
• W4309667218 cites W2023377845 @default.
• W4309667218 cites W2030633414 @default.
• W4309667218 cites W2034491578 @default.
• W4309667218 cites W2041085272 @default.
• W4309667218 cites W2042565214 @default.
• W4309667218 cites W2050021334 @default.
• W4309667218 cites W2055568104 @default.
• W4309667218 cites W2069375519 @default.
• W4309667218 cites W2076263040 @default.
• W4309667218 cites W2076832092 @default.
• W4309667218 cites W2091094291 @default.
• W4309667218 cites W2092917836 @default.
• W4309667218 cites W2110299641 @default.
• W4309667218 cites W2114050104 @default.
• W4309667218 cites W2116839388 @default.
• W4309667218 cites W2117036222 @default.
• W4309667218 cites W2131285266 @default.
• W4309667218 cites W2132152083 @default.
• W4309667218 cites W2135372888 @default.
• W4309667218 cites W2152934881 @default.
• W4309667218 cites W2161365979 @default.
• W4309667218 cites W2168851595 @default.
• W4309667218 cites W2169061346 @default.
• W4309667218 cites W2328979108 @default.
• W4309667218 cites W2518536270 @default.
• W4309667218 cites W2546040128 @default.
• W4309667218 cites W2599592635 @default.
• W4309667218 cites W2614257047 @default.
• W4309667218 cites W2771364118 @default.
• W4309667218 cites W2902125411 @default.
• W4309667218 cites W2905642696 @default.
• W4309667218 cites W3014935908 @default.
• W4309667218 cites W3113946230 @default.
• W4309667218 cites W3155288204 @default.
• W4309667218 cites W4214825861 @default.
• W4309667218 cites W4226424175 @default.
• W4309667218 cites W910906751 @default.
• W4309667218 cites W922914407 @default.
• W4309667218 doi "https://doi.org/10.1080/10253890.2022.2148100" @default.
• W4309667218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36404775" @default.
• W4309667218 hasPublicationYear "2022" @default.
• W4309667218 type Work @default.
• W4309667218 citedByCount "2" @default.
• W4309667218 countsByYear W43096672182023 @default.
• W4309667218 crossrefType "journal-article" @default.
• W4309667218 hasAuthorship W4309667218A5009337522 @default.
• W4309667218 hasAuthorship W4309667218A5031758996 @default.
• W4309667218 hasAuthorship W4309667218A5045323045 @default.
• W4309667218 hasAuthorship W4309667218A5047495439 @default.
• W4309667218 hasAuthorship W4309667218A5058957631 @default.
• W4309667218 hasAuthorship W4309667218A5059900250 @default.
• W4309667218 hasAuthorship W4309667218A5083460285 @default.
• W4309667218 hasAuthorship W4309667218A5090244949 @default.
• W4309667218 hasBestOaLocation W43096672181 @default.
• W4309667218 hasConcept C104317684 @default.
• W4309667218 hasConcept C125370674 @default.
• W4309667218 hasConcept C126322002 @default.
• W4309667218 hasConcept C151730666 @default.
• W4309667218 hasConcept C15744967 @default.
• W4309667218 hasConcept C203014093 @default.
• W4309667218 hasConcept C205545832 @default.
• W4309667218 hasConcept C2777761686 @default.
• W4309667218 hasConcept C2778488018 @default.
• W4309667218 hasConcept C2778597338 @default.
• W4309667218 hasConcept C2779343474 @default.
• W4309667218 hasConcept C2780194698 @default.
• W4309667218 hasConcept C42407357 @default.
• W4309667218 hasConcept C55493867 @default.
• W4309667218 hasConcept C70410870 @default.
• W4309667218 hasConcept C71924100 @default.
• W4309667218 hasConcept C78604142 @default.
• W4309667218 hasConcept C86803240 @default.
• W4309667218 hasConcept C8891405 @default.
• W4309667218 hasConceptScore W4309667218C104317684 @default.

• next