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• W4309677682 abstract "Cesare Gennari has contributed to many research areas in organic chemistry. On the occasion of his 70th birthday, his friends, colleagues and former students contributed to a special collection which covers his main fields of interest. Cesare Gennari turned 70 on April 19, 2022, and we celebrate his birthday with a special collection of the European Journal of Organic Chemistry, for which he has been serving for more than two decades as a member of the International Advisory Board (1998–2004, 2017–present), member of the Editorial Board (2008–2012), and chairman of the Editorial Board (2013–2016). After graduating as Doctor in Chemistry cum laude (1975), Cesare Gennari started his research activity at the University of Milan as assistant professor in the groups of Prof. Luigi Canonica and Carlo Scolastico, studying biosynthetic pathways and stereoselective synthetic routes to natural products. In 1982, he moved to the group of Prof. Clark Still at Columbia University (New York) to accomplish the total synthesis of macrocyclic trichothecanoids (baccharin B5 and roridin E).1 Here, as a side project, he developed the Z-selective variant of the Horner–Emmons olefination which today is known as the “Still–Gennari reaction”.2 Back to Italy, Cesare Gennari became associate professor (1985) and then full professor of organic chemistry at the University of Milan (1994). His research interests are very broad and he has provided important contributions to the following areas: stereoselective aldol-type reactions,3 total synthesis of biologically active natural products,4 combinatorial libraries of chiral ligands for enantioselective transition metal catalysis5 (including dynamic libraries of tropos phosphorus ligands6 and supramolecular ligands7), synthesis of peptidomimetics,8 development of peptidomimetic integrin ligands and their conjugation to cytotoxic drugs for tumor-targeting applications.9 The Gennari group is presently active in the field of targeted anti-cancer prodrugs and novel drug release systems,10 as well as of hydrogen transfer reactions promoted by base metal catalysts.11 For his work, Cesare Gennari received a number of awards, which include a NATO senior fellowship (1985), the Ciamician medal of the Organic Chemistry Division of the Italian Chemical Society (1986), the Karl Ziegler–Giulio Natta award and lecture (Gesellschaft Deutscher Chemiker & Italian Chemical Society, 1997), the Merck Frosst lecture (University of Toronto, 2005–2006), the Prize for Research in Synthetic Organic Chemistry of the Organic Chemistry Division of the Italian Chemical Society (2006), the Quilico gold medal of the Organic Chemistry Division of the Italian Chemical Society (2013), and the Piria gold medal of the Italian Chemical Society (2017). During his career, Cesare Gennari has supervised many students and taught several courses of organic chemistry, standing out as a very competent and stimulating teacher: his passion for research has inspired generations of students, who distinguished themselves in leading roles in academia and industry. Over the years, the research carried out by the Gennari group was funded by industrial, national (Italian Ministry of University and Research) and international grants (NATO and the European Commission). Besides research and teaching, Cesare Gennari has always been very committed to the scientific community: in the period 1998–2001 he was a member of the IUPAC Organic Chemistry Division Committee, since 2015 he is a Chemistry Europe Fellow, and in 2021 he was elected as a Member of Academia Europaea. In addition, Cesare Gennari was member of the consulting board of editors of Tetrahedron: Asymmetry since its foundation (1990–2017). Within the University of Milan, he served as Director of the Department of Organic and Industrial Chemistry (2008–2012), as Director of the Centre of Excellence CISI (Centro Interdipartimentale Studi biomolecolari e applicazioni industriali), and as member of the Academic Senate (2012–2018). From the short summary above, it is evident the strong motivation and dedication to organic chemistry which represent the ‘red thread’ of Cesare Gennari's career. He took seriously the warning of Daniel C. Dennett posted in his office: “The juvenile sea squirt wanders through the sea searching for a suitable rock or hunk of coral to cling to and make its home for life. For this task, it has a rudimentary nervous system. When it finds its spot and takes root, it doesn′t need its brain anymore, so it eats it! It′s rather like getting tenure.” Yet tenured and involved in many activities and duties, Cesare Gennari has never given up his commitment to knowledge and science, representing, in this sense, an example for students and colleagues. Scientific discussions with him are always challenging and demanding for students and colleagues, but also represent an invaluable ‘gym for critical thinking’ and a precious occasion of scientific growth. The opinions expressed in this publication are the view of the authors and do not necessarily reflect the opinions or views of the European Journal of Organic Chemistry, the Publisher, Chemistry Europe, or the affiliated editors. Luca Pignataro completed his PhD at the University of Milan with Prof. Franco Cozzi in 2006. After postdoc periods in the group of Prof. David Leigh (University of Edinburgh) and Prof. Cesare Gennari (University of Milan), he became Researcher (2012) and then Associate Professor (2019) at the University of Milan. His current research interests are in the fields of homogeneous catalysis (base metal catalysis, supramolecular catalysis, enantioselective catalysis, light-driven reactions), and targeted delivery of drugs (small molecule-drug conjugates for anti-tumor therapy). Umberto Piarulli obtained his PhD from the University of Lausanne in 1996 with Prof C. Floriani. In 1996 he became assistant professor of organic chemistry at Milan University and from 1998 to 2004 at the University of Insubria in Como. In 2004 he was appointed Associate Professor and in 2016 he was promoted Full Professor of Organic Chemistry. His research interests focus on stereoselective metal catalyzed synthetic methodologies, the synthesis of peptidomimetics and, more recently, the targeted delivery of drugs." @default.
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• W4309677682 date "2022-11-22" @default.
• W4309677682 modified "2023-09-27" @default.
• W4309677682 title "A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday" @default.
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