Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309697747> ?p ?o ?g. }
- W4309697747 abstract "Colorectal cancer (CRC) is a major global health problem and one of the major causes of cancer-related death worldwide. It is very important to understand the pathogenesis of CRC for early diagnosis, prevention strategies and identification of new therapeutic targets. Intercellular adhesion molecule-1 (ICAM-1, CD54) displays an important role in the the pathogenesis of CRC. It is a cell surface glycoprotein of the immunoglobulin (Ig) superfamily and plays an essential role in cell-cell, cell-extracellular matrix interaction, cell signaling and immune process. It is also expressed by tumor cells and modulates their functions, including apoptosis, cell motility, invasion and angiogenesis. The interaction between ICAM-1 and its ligand may facilitate adhesion of tumor cells to the vascular endothelium and subsequently in the promotion of metastasis. ICAM-1 expression determines malignant potential of cancer. In this review, we will discuss the expression, function, prognosis, tumorigenesis, polymorphisms and therapeutic implications of ICAM-1 in CRC." @default.
- W4309697747 created "2022-11-29" @default.
- W4309697747 creator A5003642180 @default.
- W4309697747 creator A5004533335 @default.
- W4309697747 creator A5028828034 @default.
- W4309697747 creator A5042326776 @default.
- W4309697747 creator A5045436028 @default.
- W4309697747 creator A5050645206 @default.
- W4309697747 creator A5065361552 @default.
- W4309697747 creator A5070724508 @default.
- W4309697747 creator A5075131710 @default.
- W4309697747 date "2022-11-23" @default.
- W4309697747 modified "2023-10-17" @default.
- W4309697747 title "Roles of intercellular cell adhesion molecule-1 (ICAM-1) in colorectal cancer: expression, functions, prognosis, tumorigenesis, polymorphisms and therapeutic implications" @default.
- W4309697747 cites W150182426 @default.
- W4309697747 cites W1533394020 @default.
- W4309697747 cites W1559573167 @default.
- W4309697747 cites W1626137214 @default.
- W4309697747 cites W1671590615 @default.
- W4309697747 cites W1902748641 @default.
- W4309697747 cites W1941983524 @default.
- W4309697747 cites W1946581309 @default.
- W4309697747 cites W1968347579 @default.
- W4309697747 cites W1976502086 @default.
- W4309697747 cites W1976535848 @default.
- W4309697747 cites W1980402271 @default.
- W4309697747 cites W1983654647 @default.
- W4309697747 cites W1985805477 @default.
- W4309697747 cites W1989329686 @default.
- W4309697747 cites W1998717940 @default.
- W4309697747 cites W2007551953 @default.
- W4309697747 cites W2012729913 @default.
- W4309697747 cites W2015354948 @default.
- W4309697747 cites W2026312566 @default.
- W4309697747 cites W2026843334 @default.
- W4309697747 cites W2028180911 @default.
- W4309697747 cites W2030529446 @default.
- W4309697747 cites W2033658701 @default.
- W4309697747 cites W2034607874 @default.
- W4309697747 cites W2045283830 @default.
- W4309697747 cites W2046182607 @default.
- W4309697747 cites W2053072643 @default.
- W4309697747 cites W2053942778 @default.
- W4309697747 cites W2056241741 @default.
- W4309697747 cites W2060617511 @default.
- W4309697747 cites W2060678605 @default.
- W4309697747 cites W2061056463 @default.
- W4309697747 cites W2063825866 @default.
- W4309697747 cites W2067829376 @default.
- W4309697747 cites W2069169522 @default.
- W4309697747 cites W2070164366 @default.
- W4309697747 cites W2078085938 @default.
- W4309697747 cites W2078763947 @default.
- W4309697747 cites W2083487450 @default.
- W4309697747 cites W2085226319 @default.
- W4309697747 cites W2089890651 @default.
- W4309697747 cites W2089939944 @default.
- W4309697747 cites W2092314542 @default.
- W4309697747 cites W2094816439 @default.
- W4309697747 cites W2095930897 @default.
- W4309697747 cites W2098464453 @default.
- W4309697747 cites W2100750726 @default.
- W4309697747 cites W2104101394 @default.
- W4309697747 cites W2104724504 @default.
- W4309697747 cites W2117517167 @default.
- W4309697747 cites W2122807651 @default.
- W4309697747 cites W2129536244 @default.
- W4309697747 cites W2130132119 @default.
- W4309697747 cites W2132177725 @default.
- W4309697747 cites W2133571503 @default.
- W4309697747 cites W2136556575 @default.
- W4309697747 cites W2137430929 @default.
- W4309697747 cites W2150333647 @default.
- W4309697747 cites W2150668877 @default.
- W4309697747 cites W2154643458 @default.
- W4309697747 cites W2154851868 @default.
- W4309697747 cites W2156375236 @default.
- W4309697747 cites W2158911516 @default.
- W4309697747 cites W2161114499 @default.
- W4309697747 cites W2161148715 @default.
- W4309697747 cites W2162772930 @default.
- W4309697747 cites W2165775234 @default.
- W4309697747 cites W2187639113 @default.
- W4309697747 cites W2196057440 @default.
- W4309697747 cites W2257312229 @default.
- W4309697747 cites W2302003756 @default.
- W4309697747 cites W2318671945 @default.
- W4309697747 cites W233031208 @default.
- W4309697747 cites W238827458 @default.
- W4309697747 cites W2419869435 @default.
- W4309697747 cites W2460679532 @default.
- W4309697747 cites W2581341695 @default.
- W4309697747 cites W2600201088 @default.
- W4309697747 cites W2748765754 @default.
- W4309697747 cites W2757261368 @default.
- W4309697747 cites W2774391767 @default.
- W4309697747 cites W2795491662 @default.
- W4309697747 cites W2889646458 @default.
- W4309697747 cites W2901946436 @default.
- W4309697747 cites W2945537500 @default.