Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309706564> ?p ?o ?g. }
- W4309706564 abstract "Ovarian cancer (OC) is one of the female malignancies with nearly 45% 5-year survival rate. Circular RNAs (circRNAs), a kind of single-stranded non-coding RNAs, are generated from the back-splicing of cellular housekeeping noncoding RNAs and precursor messenger RNAs. Recent studies revealed that circRNAs have different biological function, including sponging miRNAs, encoding micropeptides, regulating stability of cytoplasmic mRNAs, affecting transcription and splicing, via interacting with DNA, RNA and proteins. Due to their stability, circRNAs have the potential of acting as biomarkers and treatment targets. In this review, we briefly illustrate the biogenesis mechanism and biological function of circRNAs in OC, and make a perspective of circRNAs drug targeting immune responses and signaling pathways in OC. This article can provide a systematic view into the current situation and future of circRNAs in OC." @default.
- W4309706564 created "2022-11-29" @default.
- W4309706564 creator A5003742311 @default.
- W4309706564 creator A5014167486 @default.
- W4309706564 creator A5017353282 @default.
- W4309706564 creator A5021587684 @default.
- W4309706564 creator A5028160312 @default.
- W4309706564 creator A5040560230 @default.
- W4309706564 creator A5060664899 @default.
- W4309706564 creator A5062235790 @default.
- W4309706564 date "2022-11-23" @default.
- W4309706564 modified "2023-09-27" @default.
- W4309706564 title "Roles and mechanisms of CircRNAs in ovarian cancer" @default.
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