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• W4309715478 abstract "Autoantibodies against plasma coagulation factors could be developed by some individuals inducing severe and sometimes fatal bleedings. This clinical entity is called acquired haemophilia. It should be suspected in subjects with acute abnormal bleedings, without personal or familiar history of congenital bleeding disorders with an unexplained prolonged aPTT. It is rare disease, although its incidence may be underestimated due to the low knowledge about it by many specialists, the frequent use of anticoagulant or antiplatelet therapies in the affected population that can mask the diagnosis and, sometimes, a so withering effect that avoid its confirmation. Mortality ranges between 9% and 33% depending on the series in the first 2 months after diagnosis. This mortality is attributed in up to 40% of the cases to infections in the context of immunosuppressive treatments used to eliminate the inhibitor. Factor VIII levels below 1% and high inhibitor titers are conditions of worse response rates. Advanced age, patient's ECOG, and underlying conditions are key prognostic factors for response to treatment and patient survival. To reduce morbidity and mortality in these patients, it is important to have clinical knowledge and access to guidelines to achieve an early diagnosis and to optimize the haemostatic and immunosuppressive treatment. This review aims to contribute to the dissemination of basic concepts on the epidemiology etiopathogenesis, diagnosis, treatment and management of these patients, as well as risk factors to get remission and the longest overall survival to allow individualized care. Especial awareness will be proposed in patients with some underlying conditions like cancer, autoimmune diseases, children, pregnancy or drugs." @default.
• W4309715478 created "2022-11-29" @default.
• W4309715478 creator A5001709346 @default.
• W4309715478 creator A5052183561 @default.
• W4309715478 creator A5059021490 @default.
• W4309715478 creator A5065872523 @default.
• W4309715478 date "2022-11-01" @default.
• W4309715478 modified "2023-10-01" @default.
• W4309715478 title "Acquired Haemophilia A: A Review of What We Know" @default.
• W4309715478 cites W100012739 @default.
• W4309715478 cites W14127768 @default.
• W4309715478 cites W1497516864 @default.
• W4309715478 cites W1503453588 @default.
• W4309715478 cites W1524930492 @default.
• W4309715478 cites W1535402392 @default.
• W4309715478 cites W1569916678 @default.
• W4309715478 cites W15759395 @default.
• W4309715478 cites W1792313494 @default.
• W4309715478 cites W1854248427 @default.
• W4309715478 cites W1889292099 @default.
• W4309715478 cites W1889532155 @default.
• W4309715478 cites W1938288555 @default.
• W4309715478 cites W1964093870 @default.
• W4309715478 cites W1966981739 @default.
• W4309715478 cites W1967479627 @default.
• W4309715478 cites W1976322942 @default.
• W4309715478 cites W1993002849 @default.
• W4309715478 cites W1993662715 @default.
• W4309715478 cites W1996499278 @default.
• W4309715478 cites W1999537646 @default.
• W4309715478 cites W2000368476 @default.
• W4309715478 cites W2001205289 @default.
• W4309715478 cites W2005709386 @default.
• W4309715478 cites W2007905578 @default.
• W4309715478 cites W2008788523 @default.
• W4309715478 cites W2010561398 @default.
• W4309715478 cites W2018152369 @default.
• W4309715478 cites W2019526094 @default.
• W4309715478 cites W2021075966 @default.
• W4309715478 cites W2022724764 @default.
• W4309715478 cites W2029074737 @default.
• W4309715478 cites W2035084005 @default.
• W4309715478 cites W2035744735 @default.
• W4309715478 cites W2038329739 @default.
• W4309715478 cites W2041426282 @default.
• W4309715478 cites W2051272028 @default.
• W4309715478 cites W2068652038 @default.
• W4309715478 cites W2085939775 @default.
• W4309715478 cites W2087131972 @default.
• W4309715478 cites W2087435777 @default.
• W4309715478 cites W2094775900 @default.
• W4309715478 cites W2106656550 @default.
• W4309715478 cites W2115869789 @default.
• W4309715478 cites W2122932762 @default.
• W4309715478 cites W2128653791 @default.
• W4309715478 cites W2138267044 @default.
• W4309715478 cites W2149564822 @default.
• W4309715478 cites W2155674926 @default.
• W4309715478 cites W2157045826 @default.
• W4309715478 cites W2162535497 @default.
• W4309715478 cites W2176089507 @default.
• W4309715478 cites W2199825842 @default.
• W4309715478 cites W2212723657 @default.
• W4309715478 cites W2228999989 @default.
• W4309715478 cites W2280390418 @default.
• W4309715478 cites W2317615448 @default.
• W4309715478 cites W2319225601 @default.
• W4309715478 cites W2343666283 @default.
• W4309715478 cites W2410730751 @default.
• W4309715478 cites W2418143606 @default.
• W4309715478 cites W2419572270 @default.
• W4309715478 cites W2427589464 @default.
• W4309715478 cites W2428021776 @default.
• W4309715478 cites W2434408217 @default.
• W4309715478 cites W24561140 @default.
• W4309715478 cites W2475650002 @default.
• W4309715478 cites W2480134192 @default.
• W4309715478 cites W2494708045 @default.
• W4309715478 cites W2503868905 @default.
• W4309715478 cites W2564416890 @default.
• W4309715478 cites W2581764828 @default.
• W4309715478 cites W2607546256 @default.
• W4309715478 cites W2608375731 @default.
• W4309715478 cites W2611005000 @default.
• W4309715478 cites W2742340837 @default.
• W4309715478 cites W2760804989 @default.
• W4309715478 cites W2789446410 @default.
• W4309715478 cites W2793075683 @default.
• W4309715478 cites W2799654152 @default.
• W4309715478 cites W2803346692 @default.
• W4309715478 cites W2884269864 @default.
• W4309715478 cites W2899382220 @default.
• W4309715478 cites W2901097982 @default.
• W4309715478 cites W2904519847 @default.
• W4309715478 cites W2914044482 @default.
• W4309715478 cites W2922905002 @default.
• W4309715478 cites W2928732052 @default.
• W4309715478 cites W2965876256 @default.

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