FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309721570> ?p ?o ?g. }

• W4309721570 endingPage "3244" @default.
• W4309721570 startingPage "3244" @default.
• W4309721570 abstract "Actinobacillus pleuropneumoniae is a major economically significant bacterial respiratory pig pathogen, and whole cell vaccines are used to prevent disease. However, there is little data available on multi-serovar whole cell vaccine protection. Therefore, we determined the protective efficacies of a whole-cell A. pleuropneumoniae serovar 1 and 2 vaccine comprising ApxI-III toxins (C-vaccine, Coglapix®, Ceva, France) against serovars 1, 2, 4, 5, 6, 7, 9/11, and 13. The infection doses used induced disease representative of endemic field conditions, and standard protocols were used for all studies. Protection against homologous serovars 1 and 2 significantly reduced lung lesion scores (LLS) compared to positive controls: p = 0.00007 and p = 0.00124, respectively. The protection against heterologous serovars 4, 5, 6, 7, 9/11, and 13 also significantly reduced LLS: range p = 2.9 × 10-10 to p = 0.00953. As adjudged by the estimated random effect, reproducibility between studies was high. A highly significant serovar-independent reduction of pathological lung lesions by the C-vaccine was found for all the serovars tested (1, 2, 4, 5, 6, 7, 9/11, and 13). We conclude that the C-vaccine gives high serovar-independent protection against disease and is suitable for this use in the field." @default.
• W4309721570 created "2022-11-29" @default.
• W4309721570 creator A5018262794 @default.
• W4309721570 creator A5021341949 @default.
• W4309721570 creator A5057756077 @default.
• W4309721570 creator A5058915267 @default.
• W4309721570 creator A5061467250 @default.
• W4309721570 creator A5088231779 @default.
• W4309721570 date "2022-11-23" @default.
• W4309721570 modified "2023-09-26" @default.
• W4309721570 title "Comparative Efficacy in Challenge Dose Models of a Toxin Expressing Whole-Cell Vaccine against Eight Serovars of Actinobacillus pleuropneumoniae in Pigs" @default.
• W4309721570 cites W114568797 @default.
• W4309721570 cites W1858495354 @default.
• W4309721570 cites W1910328467 @default.
• W4309721570 cites W1951724000 @default.
• W4309721570 cites W1969851729 @default.
• W4309721570 cites W1973940228 @default.
• W4309721570 cites W1980780067 @default.
• W4309721570 cites W1985657026 @default.
• W4309721570 cites W1995388103 @default.
• W4309721570 cites W2001267854 @default.
• W4309721570 cites W2010889507 @default.
• W4309721570 cites W2021962608 @default.
• W4309721570 cites W2060408901 @default.
• W4309721570 cites W2063815552 @default.
• W4309721570 cites W2064903560 @default.
• W4309721570 cites W2073360301 @default.
• W4309721570 cites W2076503830 @default.
• W4309721570 cites W2096781556 @default.
• W4309721570 cites W2099280476 @default.
• W4309721570 cites W2102136421 @default.
• W4309721570 cites W2111563163 @default.
• W4309721570 cites W2115822590 @default.
• W4309721570 cites W2128237485 @default.
• W4309721570 cites W2137369730 @default.
• W4309721570 cites W2142752690 @default.
• W4309721570 cites W2151451423 @default.
• W4309721570 cites W2168557058 @default.
• W4309721570 cites W2171095356 @default.
• W4309721570 cites W2277777727 @default.
• W4309721570 cites W2309786286 @default.
• W4309721570 cites W2409882731 @default.
• W4309721570 cites W2767189590 @default.
• W4309721570 cites W2774486220 @default.
• W4309721570 cites W2784114096 @default.
• W4309721570 cites W2791168042 @default.
• W4309721570 cites W2792188161 @default.
• W4309721570 cites W2794314732 @default.
• W4309721570 cites W2803413988 @default.
• W4309721570 cites W2892689024 @default.
• W4309721570 cites W2995189424 @default.
• W4309721570 cites W3015431329 @default.
• W4309721570 cites W3123748025 @default.
• W4309721570 cites W3132934346 @default.
• W4309721570 cites W314475788 @default.
• W4309721570 cites W3200084026 @default.
• W4309721570 cites W3212796645 @default.
• W4309721570 cites W38460859 @default.
• W4309721570 cites W4213426522 @default.
• W4309721570 cites W4226102384 @default.
• W4309721570 cites W4249021008 @default.
• W4309721570 cites W790679672 @default.
• W4309721570 cites W1580607933 @default.
• W4309721570 doi "https://doi.org/10.3390/ani12233244" @default.
• W4309721570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36496765" @default.
• W4309721570 hasPublicationYear "2022" @default.
• W4309721570 type Work @default.
• W4309721570 citedByCount "1" @default.
• W4309721570 countsByYear W43097215702023 @default.
• W4309721570 crossrefType "journal-article" @default.
• W4309721570 hasAuthorship W4309721570A5018262794 @default.
• W4309721570 hasAuthorship W4309721570A5021341949 @default.
• W4309721570 hasAuthorship W4309721570A5057756077 @default.
• W4309721570 hasAuthorship W4309721570A5058915267 @default.
• W4309721570 hasAuthorship W4309721570A5061467250 @default.
• W4309721570 hasAuthorship W4309721570A5088231779 @default.
• W4309721570 hasBestOaLocation W43097215701 @default.
• W4309721570 hasConcept C10389963 @default.
• W4309721570 hasConcept C104317684 @default.
• W4309721570 hasConcept C159047783 @default.
• W4309721570 hasConcept C203014093 @default.
• W4309721570 hasConcept C2776460866 @default.
• W4309721570 hasConcept C2780115692 @default.
• W4309721570 hasConcept C2780728835 @default.
• W4309721570 hasConcept C2780861368 @default.
• W4309721570 hasConcept C523546767 @default.
• W4309721570 hasConcept C54355233 @default.
• W4309721570 hasConcept C55493867 @default.
• W4309721570 hasConcept C60987743 @default.
• W4309721570 hasConcept C71924100 @default.
• W4309721570 hasConcept C86803240 @default.
• W4309721570 hasConcept C89423630 @default.
• W4309721570 hasConceptScore W4309721570C10389963 @default.
• W4309721570 hasConceptScore W4309721570C104317684 @default.
• W4309721570 hasConceptScore W4309721570C159047783 @default.
• W4309721570 hasConceptScore W4309721570C203014093 @default.
• W4309721570 hasConceptScore W4309721570C2776460866 @default.
• W4309721570 hasConceptScore W4309721570C2780115692 @default.

• next