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• W4309746165 endingPage "11738" @default.
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• W4309746165 abstract "Processing wood leads to the accumulation of considerable amounts of forest waste, such as branches, leaves and especially bark. These byproducts can be exploited for their high content of biomolecules. Our aim was to histo-anatomically and phytochemically characterize the older oak bark and evaluate the potential biological activities. After the histo-anatomical characterization and processing the plant material, the aqueous and hydroalcoholic extracts were obtained using microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE). After the quantification of the total polyphenol content (TPC) and the total tannins content (TTC), the bark extracts were evaluated for antioxidant, antimicrobial and enzyme inhibitory activity. In the transverse section, the rhytidome (the succession of periderms) and the dead secondary phloem can be observed. The results of the polyphenol content of the oak bark extracts show that the hydroethanolic oak bark obtained using MAE has the highest absolute value of the TPC (347.74 mg/g). In comparison with the extracts obtained using UAE, the bark extracts obtained using MAE showed a significantly higher TPC. The greatest antioxidant and antibacterial activity were also recorded for the tested extracts. For gram-positive bacteria, the MBC values ranged from 0.3 (S. aureus) to 5 mg/mL and the oak bark extract obtained using MAE showed good activity against C. krusei (MIC—2.5 mg/mL). Among the assayed enzyme inhibitory activities, the extracts showed a significant antidiabetic effect in vitro with the highest activity corresponding to an IC50 of 3.88 µg/mL. The older oak bark represents a potential source of compounds with antibacterial, antioxidant or antidiabetic activity, which can be exploited through the biorefining processes." @default.
• W4309746165 created "2022-11-29" @default.
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• W4309746165 date "2022-11-18" @default.
• W4309746165 modified "2023-10-18" @default.
• W4309746165 title "Quercus robur Older Bark—A Source of Polyphenolic Extracts with Biological Activities" @default.
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• W4309746165 doi "https://doi.org/10.3390/app122211738" @default.
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