FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309762008> ?p ?o ?g. }

• W4309762008 endingPage "192" @default.
• W4309762008 startingPage "182" @default.
• W4309762008 abstract "In recent decades, there has been an increased interest in developing a vaccine for chikungunya. However, due to its unpredictable transmission, planning for a chikungunya vaccine trial is challenging. To inform decision making on the selection of sites for a vaccine efficacy trial, we developed a new framework for projecting the expected number of endpoint events at a given site. In this framework, we first accounted for population immunity using serological data collated from a systematic review and used it to estimate parameters related to the timing and size of past outbreaks, as predicted by an SIR transmission model. Then, we used that model to project the infection attack rate of a hypothetical future outbreak, in the event that one were to occur at the time of a future trial. This informed projections of how many endpoint events could be expected if a trial were to take place at that site. Our results suggest that some sites may have sufficient transmission potential and susceptibility to support future vaccine trials, in the event that an outbreak were to occur at those sites. In general, we conclude that sites that have experienced outbreaks within the past 10 years may be poorer targets for chikungunya vaccine efficacy trials in the near future. Our framework also generates projections of the numbers of endpoint events by age, which could inform study participant recruitment efforts." @default.
• W4309762008 created "2022-11-29" @default.
• W4309762008 creator A5011616866 @default.
• W4309762008 creator A5044963538 @default.
• W4309762008 creator A5051973944 @default.
• W4309762008 creator A5070944599 @default.
• W4309762008 creator A5071374164 @default.
• W4309762008 creator A5088884132 @default.
• W4309762008 date "2023-01-01" @default.
• W4309762008 modified "2023-09-27" @default.
• W4309762008 title "Expected endpoints from future chikungunya vaccine trial sites informed by serological data and modeling" @default.
• W4309762008 cites W1974514807 @default.
• W4309762008 cites W2006232166 @default.
• W4309762008 cites W2021307858 @default.
• W4309762008 cites W2035886603 @default.
• W4309762008 cites W2110464701 @default.
• W4309762008 cites W2115040920 @default.
• W4309762008 cites W2115054101 @default.
• W4309762008 cites W2120801593 @default.
• W4309762008 cites W2174874203 @default.
• W4309762008 cites W2299228959 @default.
• W4309762008 cites W235494447 @default.
• W4309762008 cites W2470441134 @default.
• W4309762008 cites W2560300594 @default.
• W4309762008 cites W2594220414 @default.
• W4309762008 cites W2767304872 @default.
• W4309762008 cites W2786772035 @default.
• W4309762008 cites W2803496724 @default.
• W4309762008 cites W2884353330 @default.
• W4309762008 cites W2896061359 @default.
• W4309762008 cites W2911184439 @default.
• W4309762008 cites W2911813319 @default.
• W4309762008 cites W2951825100 @default.
• W4309762008 cites W2953342850 @default.
• W4309762008 cites W2953607000 @default.
• W4309762008 cites W2953867467 @default.
• W4309762008 cites W2997947400 @default.
• W4309762008 cites W2998418911 @default.
• W4309762008 cites W3016271069 @default.
• W4309762008 cites W3038539988 @default.
• W4309762008 cites W3120738845 @default.
• W4309762008 cites W3127872908 @default.
• W4309762008 cites W3135016420 @default.
• W4309762008 cites W4205416089 @default.
• W4309762008 doi "https://doi.org/10.1016/j.vaccine.2022.11.028" @default.
• W4309762008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36424258" @default.
• W4309762008 hasPublicationYear "2023" @default.
• W4309762008 type Work @default.
• W4309762008 citedByCount "2" @default.
• W4309762008 countsByYear W43097620082023 @default.
• W4309762008 crossrefType "journal-article" @default.
• W4309762008 hasAuthorship W4309762008A5011616866 @default.
• W4309762008 hasAuthorship W4309762008A5044963538 @default.
• W4309762008 hasAuthorship W4309762008A5051973944 @default.
• W4309762008 hasAuthorship W4309762008A5070944599 @default.
• W4309762008 hasAuthorship W4309762008A5071374164 @default.
• W4309762008 hasAuthorship W4309762008A5088884132 @default.
• W4309762008 hasBestOaLocation W43097620081 @default.
• W4309762008 hasConcept C106192422 @default.
• W4309762008 hasConcept C116675565 @default.
• W4309762008 hasConcept C126322002 @default.
• W4309762008 hasConcept C159047783 @default.
• W4309762008 hasConcept C22070199 @default.
• W4309762008 hasConcept C2778190748 @default.
• W4309762008 hasConcept C2780441014 @default.
• W4309762008 hasConcept C2781273456 @default.
• W4309762008 hasConcept C2908647359 @default.
• W4309762008 hasConcept C41008148 @default.
• W4309762008 hasConcept C535046627 @default.
• W4309762008 hasConcept C71924100 @default.
• W4309762008 hasConcept C761482 @default.
• W4309762008 hasConcept C76155785 @default.
• W4309762008 hasConcept C99454951 @default.
• W4309762008 hasConceptScore W4309762008C106192422 @default.
• W4309762008 hasConceptScore W4309762008C116675565 @default.
• W4309762008 hasConceptScore W4309762008C126322002 @default.
• W4309762008 hasConceptScore W4309762008C159047783 @default.
• W4309762008 hasConceptScore W4309762008C22070199 @default.
• W4309762008 hasConceptScore W4309762008C2778190748 @default.
• W4309762008 hasConceptScore W4309762008C2780441014 @default.
• W4309762008 hasConceptScore W4309762008C2781273456 @default.
• W4309762008 hasConceptScore W4309762008C2908647359 @default.
• W4309762008 hasConceptScore W4309762008C41008148 @default.
• W4309762008 hasConceptScore W4309762008C535046627 @default.
• W4309762008 hasConceptScore W4309762008C71924100 @default.
• W4309762008 hasConceptScore W4309762008C761482 @default.
• W4309762008 hasConceptScore W4309762008C76155785 @default.
• W4309762008 hasConceptScore W4309762008C99454951 @default.
• W4309762008 hasFunder F4320332180 @default.
• W4309762008 hasIssue "1" @default.
• W4309762008 hasLocation W43097620081 @default.
• W4309762008 hasLocation W43097620082 @default.
• W4309762008 hasLocation W43097620083 @default.
• W4309762008 hasOpenAccess W4309762008 @default.
• W4309762008 hasPrimaryLocation W43097620081 @default.
• W4309762008 hasRelatedWork W2008673200 @default.
• W4309762008 hasRelatedWork W2021537194 @default.
• W4309762008 hasRelatedWork W2139341828 @default.

• next