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- W4309765510 abstract "Talquetamab is a first-in-class humanized antibody that targets both the G protein-coupled receptor class 5 member D (GPRC5D), a novel orphan receptor on malignant plasma cells, and CD3, a receptor present in T cells.1 This bispecific T-cell engager is currently being used in phase II clinical trials for the treatment of relapsed or refractory (R/R) multiple myeloma (MM). A preliminary report from a phase I clinical trial reported that 75% of treated patients had some skin-related adverse effect (all grade 3/4) with 18% being nail disorders, though there were no treatment discontinuations." @default.
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- W4309765510 date "2023-01-01" @default.
- W4309765510 modified "2023-09-30" @default.
- W4309765510 title "Onychomadesis and palmoplantar keratoderma associated with talquetamab therapy for relapsed and refractory multiple myeloma" @default.
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- W4309765510 doi "https://doi.org/10.1016/j.jdcr.2022.11.013" @default.
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