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- W4309779720 abstract "To evaluate an optimized 3D-real IR sequence with a longer TR (16,000 ms) based on the modulated flip angle technique in refocused imaging with extended echo train (MATRIX) for the endolymphatic hydrops (EH) after intravenous (IV) single-dose gadolinium (Gd) administration, and compare it with a heavily T2-weighted 3D-FLAIR sequence with a constant flip angle.The 3D-FLAIR and 3D-real IR sequences were performed in forty patients with definite Meniere's disease (MD) four hours after IV Gd administration. Image qualities of the two sequences were rated and compared. Contrast-to-noise ratios (CNRs) and signal-to-noise ratios (SNRs) of the two sequences were measured for quantitative comparison. EH was graded on the images of the two sequences by two radiologists.Scores and CNRs of the 3D-real IR were significantly higher than those of the 3D-FLAIR (P < 0.05). SNRs of the two sequences were comparable between the two groups. 3D-real IR had a higher inter- and intra-observer reliability for the grading of cochlear and vestibular EH than 3D-FLAIR. Using 3D-real IR sequence, the detection rate of EH of the whole labyrinth was higher than using 3D-FLAIR (86.6 % vs 73.3 %, p = 0.031). In the patients with unilateral MD, SNRs in the affected sides were significantly higher than the unaffected sides (P < 0.05).The optimized 3D-real IR with a longer TR is a robust sequence with an improved depiction of EH after IV administration of single-dose Gd. Compared with 3D-FLAIR, it may allow a more precise evaluation and grading of EH." @default.
- W4309779720 created "2022-11-29" @default.
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- W4309779720 date "2023-01-01" @default.
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- W4309779720 title "Comparison of an optimized 3D-real IR and a 3D-FLAIR with a constant flip angle in the evaluation of endolymphatic hydrops" @default.
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- W4309779720 doi "https://doi.org/10.1016/j.ejrad.2022.110614" @default.
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