Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309787582> ?p ?o ?g. }
- W4309787582 endingPage "1659" @default.
- W4309787582 startingPage "1659" @default.
- W4309787582 abstract "Background and Objectives: Chronic hemodialysis (CHD) patients are at increased risk of SARS-CoV-2 infection and the related complications and mortality of COVID-19 due to the high rate of comorbidities combined with advanced age. This observational study investigated the clinical manifestations of SARS-CoV-2 infection in CHD and the risk factors for patients′ death. Materials and Methods: The study included 26 CHD patients with SARS-CoV-2 pneumonia detected by positive RT-PCR on nasopharyngeal swabs and high-resolution computed tomography at hospital admission, aged 71 + 5.9 years, 14 of which (53.8%) were male, 20 (77%) under hemodiafiltration, and 6 (23%) on standard hemodialysis, with a median follow-up of 30 days. Results: Simple logistic regression analysis revealed that the factors associated with a higher risk of death were older age (OR: 1.133; 95%CI: 1.028−1.326, p = 0.0057), IL-6 levels at admission (OR: 1.014; 95%CI: 1.004−1.028, p = 0.0053), and C-reactive protein (OR: 1.424; 95%CI: 1.158−2.044, p < 0.0001). In the multiple logistic regression model, circulating IL-6 values at admission remained the only significant prognosticator of death. The ROC curve indicated the discriminatory cut-off value of 38.20 pg/mL of blood IL-6 for predicting death in chronic hemodialysis patients with SARS-CoV-2 pneumonia (sensitivity: 100%; specificity: 78%; AUC: 0.8750; p = 0.0027). Conclusions: This study identified a threshold of IL-6 levels at hospital admission for death risk in CHD patients with SARS-CoV-2 pneumonia. This might represent a valuable outcome predictor, feasibly better than other clinical, radiological, or laboratory parameters and preceding the IL-6 peak, which is unpredictable." @default.
- W4309787582 created "2022-11-29" @default.
- W4309787582 creator A5005301540 @default.
- W4309787582 creator A5014721120 @default.
- W4309787582 creator A5015826182 @default.
- W4309787582 creator A5024319333 @default.
- W4309787582 creator A5025909416 @default.
- W4309787582 creator A5039621451 @default.
- W4309787582 creator A5053420948 @default.
- W4309787582 creator A5066868536 @default.
- W4309787582 creator A5091858025 @default.
- W4309787582 date "2022-11-16" @default.
- W4309787582 modified "2023-10-18" @default.
- W4309787582 title "Interleukin-6 and Outcome of Chronic Hemodialysis Patients with SARS-CoV-2 Pneumonia" @default.
- W4309787582 cites W1504677535 @default.
- W4309787582 cites W1518874831 @default.
- W4309787582 cites W1976884472 @default.
- W4309787582 cites W1984451352 @default.
- W4309787582 cites W1985292239 @default.
- W4309787582 cites W2000445173 @default.
- W4309787582 cites W2009866154 @default.
- W4309787582 cites W2045697012 @default.
- W4309787582 cites W2070334286 @default.
- W4309787582 cites W2134217123 @default.
- W4309787582 cites W2157679325 @default.
- W4309787582 cites W2167215662 @default.
- W4309787582 cites W2904356389 @default.
- W4309787582 cites W3006961006 @default.
- W4309787582 cites W3012849736 @default.
- W4309787582 cites W3016538467 @default.
- W4309787582 cites W3017086311 @default.
- W4309787582 cites W3019785070 @default.
- W4309787582 cites W3021778339 @default.
- W4309787582 cites W3021998249 @default.
- W4309787582 cites W3023564114 @default.
- W4309787582 cites W3025160648 @default.
- W4309787582 cites W3027377573 @default.
- W4309787582 cites W3035340743 @default.
- W4309787582 cites W3044304208 @default.
- W4309787582 cites W3080981445 @default.
- W4309787582 cites W3085420778 @default.
- W4309787582 cites W3095404113 @default.
- W4309787582 cites W3124612763 @default.
- W4309787582 cites W3125991701 @default.
- W4309787582 cites W3136475830 @default.
- W4309787582 cites W3186912398 @default.
- W4309787582 cites W3194768904 @default.
- W4309787582 cites W4224981651 @default.
- W4309787582 cites W4281636382 @default.
- W4309787582 doi "https://doi.org/10.3390/medicina58111659" @default.
- W4309787582 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36422198" @default.
- W4309787582 hasPublicationYear "2022" @default.
- W4309787582 type Work @default.
- W4309787582 citedByCount "0" @default.
- W4309787582 crossrefType "journal-article" @default.
- W4309787582 hasAuthorship W4309787582A5005301540 @default.
- W4309787582 hasAuthorship W4309787582A5014721120 @default.
- W4309787582 hasAuthorship W4309787582A5015826182 @default.
- W4309787582 hasAuthorship W4309787582A5024319333 @default.
- W4309787582 hasAuthorship W4309787582A5025909416 @default.
- W4309787582 hasAuthorship W4309787582A5039621451 @default.
- W4309787582 hasAuthorship W4309787582A5053420948 @default.
- W4309787582 hasAuthorship W4309787582A5066868536 @default.
- W4309787582 hasAuthorship W4309787582A5091858025 @default.
- W4309787582 hasBestOaLocation W43097875821 @default.
- W4309787582 hasConcept C126322002 @default.
- W4309787582 hasConcept C151956035 @default.
- W4309787582 hasConcept C179755657 @default.
- W4309787582 hasConcept C23131810 @default.
- W4309787582 hasConcept C2777914695 @default.
- W4309787582 hasConcept C2778063415 @default.
- W4309787582 hasConcept C50440223 @default.
- W4309787582 hasConcept C71924100 @default.
- W4309787582 hasConcept C90924648 @default.
- W4309787582 hasConceptScore W4309787582C126322002 @default.
- W4309787582 hasConceptScore W4309787582C151956035 @default.
- W4309787582 hasConceptScore W4309787582C179755657 @default.
- W4309787582 hasConceptScore W4309787582C23131810 @default.
- W4309787582 hasConceptScore W4309787582C2777914695 @default.
- W4309787582 hasConceptScore W4309787582C2778063415 @default.
- W4309787582 hasConceptScore W4309787582C50440223 @default.
- W4309787582 hasConceptScore W4309787582C71924100 @default.
- W4309787582 hasConceptScore W4309787582C90924648 @default.
- W4309787582 hasIssue "11" @default.
- W4309787582 hasLocation W43097875821 @default.
- W4309787582 hasLocation W43097875822 @default.
- W4309787582 hasLocation W43097875823 @default.
- W4309787582 hasLocation W43097875824 @default.
- W4309787582 hasLocation W43097875825 @default.
- W4309787582 hasOpenAccess W4309787582 @default.
- W4309787582 hasPrimaryLocation W43097875821 @default.
- W4309787582 hasRelatedWork W113810927 @default.
- W4309787582 hasRelatedWork W1984576678 @default.
- W4309787582 hasRelatedWork W1989911654 @default.
- W4309787582 hasRelatedWork W2025499134 @default.
- W4309787582 hasRelatedWork W2029508538 @default.
- W4309787582 hasRelatedWork W2324506294 @default.
- W4309787582 hasRelatedWork W2371478958 @default.