FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309796564> ?p ?o ?g. }

• W4309796564 endingPage "114225" @default.
• W4309796564 startingPage "114225" @default.
• W4309796564 abstract "Prenatal stress is a critical life event often resulting in mental illnesses in the offspring. The critical developmental processes, which might trigger a cascade of molecular events resulting in mental disorders in adulthood, are still to be elucidated. Here we proposed that sex hormones, particularly testosterone, might determine the “developmental programming” of long-term consequences of prenatal stress in foetuses of both sexes. We observed that severe prenatal stress in the model of repeated corticosterone injections enhanced brain levels of corticosterone and testosterone in male foetuses. The expression of GluN1 and GluN2A, but not GluN2B NMDA receptor subunits were significantly reduced in the brain of stressed male foetuses. However, female foetuses were protected against stress effects on the brain corticosterone and testosterone levels. More moderate types of stress, such as repeated restraint stress and chronic unpredictable stress, did not induce an increase in brain corticosterone in dams and testosterone concentrations in foetuses of both sexes. Moreover, chronic unpredictable stress reduced brain testosterone concentration in male foetuses. Altogether, changes in brain testosterone level might be one of the crucial mechanisms determining the development of long-term consequences of severe prenatal stress in male, but not in female foetuses. Targeting this mechanism might allow to develop principally new prediction and therapeutic approaches for prenatal stress-associated psychiatric disorders." @default.
• W4309796564 created "2022-11-29" @default.
• W4309796564 creator A5040729812 @default.
• W4309796564 creator A5047448447 @default.
• W4309796564 creator A5053681854 @default.
• W4309796564 creator A5065088202 @default.
• W4309796564 creator A5067913949 @default.
• W4309796564 creator A5078328219 @default.
• W4309796564 date "2023-02-01" @default.
• W4309796564 modified "2023-10-14" @default.
• W4309796564 title "Sex-specific effects of different types of prenatal stress on foetal testosterone levels and NMDA expression in mice" @default.
• W4309796564 cites W1834035763 @default.
• W4309796564 cites W1917336488 @default.
• W4309796564 cites W1966757737 @default.
• W4309796564 cites W1978820887 @default.
• W4309796564 cites W1981274985 @default.
• W4309796564 cites W2004684279 @default.
• W4309796564 cites W2006268333 @default.
• W4309796564 cites W2010877246 @default.
• W4309796564 cites W2014616136 @default.
• W4309796564 cites W2032679733 @default.
• W4309796564 cites W2044219781 @default.
• W4309796564 cites W2045667106 @default.
• W4309796564 cites W2050045288 @default.
• W4309796564 cites W2051026082 @default.
• W4309796564 cites W2072391746 @default.
• W4309796564 cites W2074397578 @default.
• W4309796564 cites W2089545863 @default.
• W4309796564 cites W2093475197 @default.
• W4309796564 cites W2120310035 @default.
• W4309796564 cites W2121403142 @default.
• W4309796564 cites W2130817201 @default.
• W4309796564 cites W2134706785 @default.
• W4309796564 cites W2138294571 @default.
• W4309796564 cites W2145691687 @default.
• W4309796564 cites W2507945432 @default.
• W4309796564 cites W2604594728 @default.
• W4309796564 cites W2604652480 @default.
• W4309796564 cites W2605110584 @default.
• W4309796564 cites W2743803344 @default.
• W4309796564 cites W2769945558 @default.
• W4309796564 cites W2770575058 @default.
• W4309796564 cites W2793357593 @default.
• W4309796564 cites W2795881597 @default.
• W4309796564 cites W2942191604 @default.
• W4309796564 cites W3092223327 @default.
• W4309796564 cites W3164359378 @default.
• W4309796564 cites W84932982 @default.
• W4309796564 doi "https://doi.org/10.1016/j.bbr.2022.114225" @default.
• W4309796564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36435218" @default.
• W4309796564 hasPublicationYear "2023" @default.
• W4309796564 type Work @default.
• W4309796564 citedByCount "1" @default.
• W4309796564 countsByYear W43097965642023 @default.
• W4309796564 crossrefType "journal-article" @default.
• W4309796564 hasAuthorship W4309796564A5040729812 @default.
• W4309796564 hasAuthorship W4309796564A5047448447 @default.
• W4309796564 hasAuthorship W4309796564A5053681854 @default.
• W4309796564 hasAuthorship W4309796564A5065088202 @default.
• W4309796564 hasAuthorship W4309796564A5067913949 @default.
• W4309796564 hasAuthorship W4309796564A5078328219 @default.
• W4309796564 hasConcept C104317684 @default.
• W4309796564 hasConcept C112672928 @default.
• W4309796564 hasConcept C126322002 @default.
• W4309796564 hasConcept C134018914 @default.
• W4309796564 hasConcept C15744967 @default.
• W4309796564 hasConcept C170493617 @default.
• W4309796564 hasConcept C172680121 @default.
• W4309796564 hasConcept C2776443723 @default.
• W4309796564 hasConcept C2778654844 @default.
• W4309796564 hasConcept C2778945730 @default.
• W4309796564 hasConcept C2779234561 @default.
• W4309796564 hasConcept C2779279991 @default.
• W4309796564 hasConcept C2780352252 @default.
• W4309796564 hasConcept C54355233 @default.
• W4309796564 hasConcept C63405245 @default.
• W4309796564 hasConcept C67018056 @default.
• W4309796564 hasConcept C71315377 @default.
• W4309796564 hasConcept C71924100 @default.
• W4309796564 hasConcept C86803240 @default.
• W4309796564 hasConceptScore W4309796564C104317684 @default.
• W4309796564 hasConceptScore W4309796564C112672928 @default.
• W4309796564 hasConceptScore W4309796564C126322002 @default.
• W4309796564 hasConceptScore W4309796564C134018914 @default.
• W4309796564 hasConceptScore W4309796564C15744967 @default.
• W4309796564 hasConceptScore W4309796564C170493617 @default.
• W4309796564 hasConceptScore W4309796564C172680121 @default.
• W4309796564 hasConceptScore W4309796564C2776443723 @default.
• W4309796564 hasConceptScore W4309796564C2778654844 @default.
• W4309796564 hasConceptScore W4309796564C2778945730 @default.
• W4309796564 hasConceptScore W4309796564C2779234561 @default.
• W4309796564 hasConceptScore W4309796564C2779279991 @default.
• W4309796564 hasConceptScore W4309796564C2780352252 @default.
• W4309796564 hasConceptScore W4309796564C54355233 @default.
• W4309796564 hasConceptScore W4309796564C63405245 @default.
• W4309796564 hasConceptScore W4309796564C67018056 @default.
• W4309796564 hasConceptScore W4309796564C71315377 @default.
• W4309796564 hasConceptScore W4309796564C71924100 @default.

• next