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- W4309809344 abstract "There is now a deeper understanding of the biology of hormone receptor-positive (HR+) early breast cancer (EBC) that can be used to inform assessment of risk and prognosis, and also guide more effective adjuvant systemic therapies. For postmenopausal HR+ EBC endocrine therapy remains the mainstay of treatment with extended duration up to 10 years for some, the addition of targeted CDK 4/6 inhibitors for those with node-positive high-risk disease, and de-escalation of chemotherapy use for those in whom it is unlikely to be of benefit. As such, systemic adjuvant therapy is now highly tailored and individualized." @default.
- W4309809344 created "2022-11-29" @default.
- W4309809344 creator A5031915637 @default.
- W4309809344 date "2023-02-01" @default.
- W4309809344 modified "2023-09-30" @default.
- W4309809344 title "Adjuvant Systemic Therapy for Postmenopausal, Hormone Receptor-Positive Early Breast Cancer" @default.
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- W4309809344 doi "https://doi.org/10.1016/j.hoc.2022.08.011" @default.
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