Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309825902> ?p ?o ?g. }
- W4309825902 endingPage "235" @default.
- W4309825902 startingPage "220" @default.
- W4309825902 abstract "The present study interrogates the interaction of highly efficient antibacterial surfaces containing sharp nanostructures with blood proteins and the subsequent immunological consequences, processes that are of key importance for the fate of every implantable biomaterial. Studies with human serum and plasma pointed to significant differences in the composition of the protein corona that formed on control and nanostructured surfaces. Quantitative analysis using liquid chromatography-mass spectrometry demonstrated that the nanostructured surface attracted more vitronectin and less complement proteins compared to the untreated control. In turn, the protein corona composition modulated the adhesion and cytokine expression by immune cells. Monocytes produced lower amounts of pro-inflammatory cytokines and expressed more anti-inflammatory factors on the nanostructured surface. Studies using an in vivo subcutaneous mouse model showed reduced fibrous capsule thickness which could be a consequence of the attenuated inflammatory response. The results from this work suggest that antibacterial surface modification with sharp spike-like nanostructures may not only lead to the reduction of inflammation but also more favorable foreign body response and enhanced healing, processes that are beneficial for most medical devices implanted in patients." @default.
- W4309825902 created "2022-11-29" @default.
- W4309825902 creator A5021592265 @default.
- W4309825902 creator A5023571108 @default.
- W4309825902 creator A5029289255 @default.
- W4309825902 creator A5034838011 @default.
- W4309825902 creator A5044972470 @default.
- W4309825902 creator A5053094632 @default.
- W4309825902 creator A5053405743 @default.
- W4309825902 creator A5053551404 @default.
- W4309825902 creator A5058037382 @default.
- W4309825902 creator A5066247225 @default.
- W4309825902 creator A5067098032 @default.
- W4309825902 creator A5067460447 @default.
- W4309825902 creator A5069208263 @default.
- W4309825902 creator A5070931998 @default.
- W4309825902 creator A5091503891 @default.
- W4309825902 creator A5091697678 @default.
- W4309825902 date "2022-11-23" @default.
- W4309825902 modified "2023-10-16" @default.
- W4309825902 title "Antibacterial Nanostructured Surfaces Modulate Protein Adsorption, Inflammatory Responses, and Fibrous Capsule Formation" @default.
- W4309825902 cites W1835697155 @default.
- W4309825902 cites W1968479079 @default.
- W4309825902 cites W1973474133 @default.
- W4309825902 cites W1982912398 @default.
- W4309825902 cites W2000293251 @default.
- W4309825902 cites W2021102901 @default.
- W4309825902 cites W2030290965 @default.
- W4309825902 cites W2031041031 @default.
- W4309825902 cites W2031876019 @default.
- W4309825902 cites W2039657186 @default.
- W4309825902 cites W2045383620 @default.
- W4309825902 cites W2048361405 @default.
- W4309825902 cites W2051239218 @default.
- W4309825902 cites W2054468082 @default.
- W4309825902 cites W2059542554 @default.
- W4309825902 cites W2062316046 @default.
- W4309825902 cites W2064413925 @default.
- W4309825902 cites W2067719770 @default.
- W4309825902 cites W2074150439 @default.
- W4309825902 cites W2078774546 @default.
- W4309825902 cites W2079236567 @default.
- W4309825902 cites W2085099489 @default.
- W4309825902 cites W2093883262 @default.
- W4309825902 cites W2096147603 @default.
- W4309825902 cites W2104101524 @default.
- W4309825902 cites W2140616239 @default.
- W4309825902 cites W2141547848 @default.
- W4309825902 cites W2144076105 @default.
- W4309825902 cites W2146726585 @default.
- W4309825902 cites W2155023684 @default.
- W4309825902 cites W2158204011 @default.
- W4309825902 cites W2159226235 @default.
- W4309825902 cites W2165462684 @default.
- W4309825902 cites W2167830630 @default.
- W4309825902 cites W2168715036 @default.
- W4309825902 cites W2284550715 @default.
- W4309825902 cites W2543049806 @default.
- W4309825902 cites W2606910875 @default.
- W4309825902 cites W2740273888 @default.
- W4309825902 cites W2769795640 @default.
- W4309825902 cites W2807815519 @default.
- W4309825902 cites W2883780478 @default.
- W4309825902 cites W2897232908 @default.
- W4309825902 cites W2898677184 @default.
- W4309825902 cites W2901224488 @default.
- W4309825902 cites W2907835634 @default.
- W4309825902 cites W2913468211 @default.
- W4309825902 cites W2954652909 @default.
- W4309825902 cites W2957779183 @default.
- W4309825902 cites W2980291122 @default.
- W4309825902 cites W3120717874 @default.
- W4309825902 cites W3141681677 @default.
- W4309825902 cites W3177044329 @default.
- W4309825902 cites W3193184482 @default.
- W4309825902 cites W3207331436 @default.
- W4309825902 cites W4210324463 @default.
- W4309825902 cites W4210512976 @default.
- W4309825902 cites W4230633835 @default.
- W4309825902 cites W4244568820 @default.
- W4309825902 cites W4281290481 @default.
- W4309825902 doi "https://doi.org/10.1021/acsami.2c13415" @default.
- W4309825902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36416784" @default.
- W4309825902 hasPublicationYear "2022" @default.
- W4309825902 type Work @default.
- W4309825902 citedByCount "2" @default.
- W4309825902 countsByYear W43098259022023 @default.
- W4309825902 crossrefType "journal-article" @default.
- W4309825902 hasAuthorship W4309825902A5021592265 @default.
- W4309825902 hasAuthorship W4309825902A5023571108 @default.
- W4309825902 hasAuthorship W4309825902A5029289255 @default.
- W4309825902 hasAuthorship W4309825902A5034838011 @default.
- W4309825902 hasAuthorship W4309825902A5044972470 @default.
- W4309825902 hasAuthorship W4309825902A5053094632 @default.
- W4309825902 hasAuthorship W4309825902A5053405743 @default.
- W4309825902 hasAuthorship W4309825902A5053551404 @default.
- W4309825902 hasAuthorship W4309825902A5058037382 @default.
- W4309825902 hasAuthorship W4309825902A5066247225 @default.