FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4309840119> ?p ?o ?g. }

• W4309840119 abstract "Introduction The Markhoz goat is the only breed that can produce high-quality fiber called mohair in Iran; however, the size of its population has faced a dramatic decline during the last decades, mainly due to the reluctance of farmers to rear Markhoz goats caused by a reduction in goat production income. Litter size at birth (LSB) and weaning (LSW) are two economically important reproductive traits for local goat breeders and have the potential of increasing the population growth rate. The present study was aimed to identify possible genomic regions that are associated with LSB and LSW in Markhoz goats using a genome-wide association study (GWAS). Methods To this end, 136 Markhoz goats with record(s) of kidding were selected for GWAS using the Illumina Caprine 50K bead chip. The individual breeding values (BV) of available LSB and LSW records estimated under an animal mixed model were used as the dependent variable in the GWAS, thereby incorporating repeated categorical variables of litter size. Results Four SNPs on chromosomes 2, 20 and 21 were identified to be significantly associated (FDR p &lt; 0.05) with LSB after multiple testing correction under a Bayesian-information and Linkage-disequilibrium Iteratively Nested Keyway (BLINK) model. Least-square analysis was performed to investigate the effects of detected genotypes on LSB. Ultimately, the GWAS results introduced six candidate genes, including GABRA5, AKAP13, SV2B, PPP1R1C, SSFA2 and TRNAS-GCU in a 100 kb adjacent region of the identified SNPs. Previous studies proposed functional roles of GABRA5 and AKAP13 genes in reproductive processes; however, the role of other candidate genes in reproduction is not clear. Conclusion These findings warrant further investigation for use in marker-assisted selection programs in Markhoz goats." @default.
• W4309840119 created "2022-11-29" @default.
• W4309840119 creator A5046416396 @default.
• W4309840119 creator A5067614432 @default.
• W4309840119 creator A5067879872 @default.
• W4309840119 creator A5075293688 @default.
• W4309840119 creator A5077572089 @default.
• W4309840119 creator A5082223499 @default.
• W4309840119 date "2022-11-23" @default.
• W4309840119 modified "2023-09-25" @default.
• W4309840119 title "Genome-wide association study reveals novel candidate genes for litter size in Markhoz goats" @default.
• W4309840119 cites W1975315797 @default.
• W4309840119 cites W2017746811 @default.
• W4309840119 cites W2029709883 @default.
• W4309840119 cites W2030963277 @default.
• W4309840119 cites W2033151532 @default.
• W4309840119 cites W2035168188 @default.
• W4309840119 cites W2039538586 @default.
• W4309840119 cites W2050773624 @default.
• W4309840119 cites W2072524765 @default.
• W4309840119 cites W2074592806 @default.
• W4309840119 cites W2074956582 @default.
• W4309840119 cites W2083781689 @default.
• W4309840119 cites W2117331379 @default.
• W4309840119 cites W2135581544 @default.
• W4309840119 cites W2166890160 @default.
• W4309840119 cites W2252512272 @default.
• W4309840119 cites W2279222810 @default.
• W4309840119 cites W2594081754 @default.
• W4309840119 cites W2770180412 @default.
• W4309840119 cites W2795787441 @default.
• W4309840119 cites W2796713079 @default.
• W4309840119 cites W2809201892 @default.
• W4309840119 cites W2887181769 @default.
• W4309840119 cites W2901957554 @default.
• W4309840119 cites W2921463600 @default.
• W4309840119 cites W2953380456 @default.
• W4309840119 cites W2954752112 @default.
• W4309840119 cites W2966132762 @default.
• W4309840119 cites W2979729245 @default.
• W4309840119 cites W3010495972 @default.
• W4309840119 cites W3033340958 @default.
• W4309840119 cites W3084034398 @default.
• W4309840119 cites W4232711648 @default.
• W4309840119 cites W4242289937 @default.
• W4309840119 doi "https://doi.org/10.3389/fvets.2022.1045589" @default.
• W4309840119 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36504837" @default.
• W4309840119 hasPublicationYear "2022" @default.
• W4309840119 type Work @default.
• W4309840119 citedByCount "2" @default.
• W4309840119 countsByYear W43098401192023 @default.
• W4309840119 crossrefType "journal-article" @default.
• W4309840119 hasAuthorship W4309840119A5046416396 @default.
• W4309840119 hasAuthorship W4309840119A5067614432 @default.
• W4309840119 hasAuthorship W4309840119A5067879872 @default.
• W4309840119 hasAuthorship W4309840119A5075293688 @default.
• W4309840119 hasAuthorship W4309840119A5077572089 @default.
• W4309840119 hasAuthorship W4309840119A5082223499 @default.
• W4309840119 hasBestOaLocation W43098401191 @default.
• W4309840119 hasConcept C104317684 @default.
• W4309840119 hasConcept C106208931 @default.
• W4309840119 hasConcept C135763542 @default.
• W4309840119 hasConcept C153209595 @default.
• W4309840119 hasConcept C186413461 @default.
• W4309840119 hasConcept C18903297 @default.
• W4309840119 hasConcept C2779429622 @default.
• W4309840119 hasConcept C2908647359 @default.
• W4309840119 hasConcept C35605836 @default.
• W4309840119 hasConcept C54355233 @default.
• W4309840119 hasConcept C69991583 @default.
• W4309840119 hasConcept C71924100 @default.
• W4309840119 hasConcept C86803240 @default.
• W4309840119 hasConcept C99454951 @default.
• W4309840119 hasConceptScore W4309840119C104317684 @default.
• W4309840119 hasConceptScore W4309840119C106208931 @default.
• W4309840119 hasConceptScore W4309840119C135763542 @default.
• W4309840119 hasConceptScore W4309840119C153209595 @default.
• W4309840119 hasConceptScore W4309840119C186413461 @default.
• W4309840119 hasConceptScore W4309840119C18903297 @default.
• W4309840119 hasConceptScore W4309840119C2779429622 @default.
• W4309840119 hasConceptScore W4309840119C2908647359 @default.
• W4309840119 hasConceptScore W4309840119C35605836 @default.
• W4309840119 hasConceptScore W4309840119C54355233 @default.
• W4309840119 hasConceptScore W4309840119C69991583 @default.
• W4309840119 hasConceptScore W4309840119C71924100 @default.
• W4309840119 hasConceptScore W4309840119C86803240 @default.
• W4309840119 hasConceptScore W4309840119C99454951 @default.
• W4309840119 hasLocation W43098401191 @default.
• W4309840119 hasLocation W43098401192 @default.
• W4309840119 hasLocation W43098401193 @default.
• W4309840119 hasLocation W43098401194 @default.
• W4309840119 hasLocation W43098401195 @default.
• W4309840119 hasOpenAccess W4309840119 @default.
• W4309840119 hasPrimaryLocation W43098401191 @default.
• W4309840119 hasRelatedWork W1633169450 @default.
• W4309840119 hasRelatedWork W2002310179 @default.
• W4309840119 hasRelatedWork W2030117176 @default.
• W4309840119 hasRelatedWork W2169474281 @default.
• W4309840119 hasRelatedWork W2914786177 @default.
• W4309840119 hasRelatedWork W3003328317 @default.

• next