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• W4309989474 abstract "Abstract Objective Ultrasound can detect individual motor unit (MU) activity during voluntary isometric contractions based on their subtle axial displacements. The detection pipeline, currently performed offline, is based on displacement velocity images and identifying the subtle axial displacements. This identification can preferably be made through a blind source separation (BSS) algorithm with the feasibility of translating the pipeline from offline to online . However, the question remains how to reduce the computational time for the BSS algorithm, which includes demixing tissue velocities from many different sources, e.g., the active MU displacements, arterial pulsations, bones, connective tissue, and noise. Approach This study proposes a fast velocity-based BSS (velBSS) algorithm suitable for online purposes that decomposes velocity images from low-force voluntary isometric contractions into spatiotemporal components associated with single MU activities. The proposed algorithm will be compared against stICA, i.e., the method used in previous papers, for various subjects, ultrasound- and EMG systems, where the latter acts as MU reference recordings. Main results We found that the spatial and temporal correlation between the MU-associated components from velBSS and stICA was high (0.86 ± 0.05 and 0.87 ± 0.06). The spike-triggered averaged twitch responses (using the MU spike trains from EMG) had an extremely high correlation (0.99 ± 0.01). In addition, the computational time for velBSS was at least 50 times less than for stICA. Significance The present algorithm (velBSS) outperforms the currently available method (stICA). It provides a promising translation towards an online pipeline and will be important in the continued development of this research field of functional neuromuscular imaging." @default.
• W4309989474 created "2022-11-30" @default.
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• W4309989474 date "2022-11-24" @default.
• W4309989474 modified "2023-09-28" @default.
• W4309989474 title "A fast blind source separation algorithm for decomposing ultrafast ultrasound images into spatiotemporal muscle unit kinematics" @default.
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• W4309989474 doi "https://doi.org/10.1101/2022.11.22.517488" @default.
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