FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310030107> ?p ?o ?g. }

• W4310030107 abstract "Abstract Objectives Several countries have authorized a booster vaccine campaign to combat the spread of COVID-19. Data on persistence of booster vaccine-induced immunity against new Omicron subvariants are still limited. Therefore, our study aimed to determine the serological immune response of COVID-19 booster after CoronaVac-priming. Methods A total of 187 CoronaVac-primed participants were enrolled and received an inactivated (BBIBP), viral vector (AZD1222) or mRNA vaccine (full-/half-dose BNT162B2, full-/half-dose mRNA-1273) as a booster dose. The persistence of humoral immunity both binding and neutralizing antibodies against wild-type and Omicron was determined on day 90– 120 after booster. Results A waning of total RBD immunoglobulin (Ig) levels, anti-RBD IgG, and neutralizing antibodies against Omicron BA.1, BA.2, and BA.4/5 variants was observed 90–120 days after booster vaccination. Participants who received mRNA-1273 had the highest persistence of the immunogenicity response, followed by BNT162b2, AZD1222, and BBIBP-CorV. The responses between full and half doses of mRNA-1273 were comparable. The percentage reduction of binding antibody ranged from 50% to 75% among all booster vaccine. Conclusions The antibody response substantially waned after 90–120 days post-booster dose. The heterologous mRNA and the viral vector booster demonstrated higher detectable rate of humoral immune responses against the Omicron variant compared to the inactivated BBIBP booster. Nevertheless, an additional fourth dose is recommended to maintain immune response against infection. Highlights The persistence of antibody responses is different among three vaccine platforms. Highly remained antibody levels were observed with the mRNA and viral vector booster. The half-dose mRNA-1273 can be used interchangeably with the full-dose mRNA-1273. The neutralizing activity against BA.5 was lower than wild type and BA.2 subvariant. A fourth dose is recommended for individuals who received an inactivated booster." @default.
• W4310030107 created "2022-11-30" @default.
• W4310030107 creator A5000380009 @default.
• W4310030107 creator A5001340042 @default.
• W4310030107 creator A5004143697 @default.
• W4310030107 creator A5006530955 @default.
• W4310030107 creator A5012247460 @default.
• W4310030107 creator A5024970229 @default.
• W4310030107 creator A5026081538 @default.
• W4310030107 creator A5026707377 @default.
• W4310030107 creator A5038016690 @default.
• W4310030107 creator A5059959150 @default.
• W4310030107 creator A5066359846 @default.
• W4310030107 creator A5067372935 @default.
• W4310030107 creator A5067511913 @default.
• W4310030107 creator A5067543646 @default.
• W4310030107 creator A5072307927 @default.
• W4310030107 creator A5078469285 @default.
• W4310030107 creator A5082135516 @default.
• W4310030107 creator A5084305363 @default.
• W4310030107 creator A5090299749 @default.
• W4310030107 date "2022-11-27" @default.
• W4310030107 modified "2023-10-15" @default.
• W4310030107 title "Immunogenicity and durability against Omicron BA.1, BA.2 and BA.4/5 variants at 3 to 4 months after a heterologous COVID-19 booster vaccine in healthy adults with a two-doses CoronaVac vaccination" @default.
• W4310030107 cites W3135594926 @default.
• W4310030107 cites W3163785571 @default.
• W4310030107 cites W3164547793 @default.
• W4310030107 cites W3200674187 @default.
• W4310030107 cites W4200180765 @default.
• W4310030107 cites W4200505933 @default.
• W4310030107 cites W4205283268 @default.
• W4310030107 cites W4210844692 @default.
• W4310030107 cites W4220886289 @default.
• W4310030107 cites W4221072241 @default.
• W4310030107 cites W4223599029 @default.
• W4310030107 cites W4225266546 @default.
• W4310030107 cites W4225424875 @default.
• W4310030107 cites W4225472009 @default.
• W4310030107 cites W4225505308 @default.
• W4310030107 cites W4225691034 @default.
• W4310030107 cites W4229363592 @default.
• W4310030107 cites W4281622942 @default.
• W4310030107 cites W4283381154 @default.
• W4310030107 cites W4285803421 @default.
• W4310030107 cites W4285808982 @default.
• W4310030107 cites W4292553247 @default.
• W4310030107 cites W4293764185 @default.
• W4310030107 cites W4294908418 @default.
• W4310030107 cites W4295420158 @default.
• W4310030107 cites W4296983281 @default.
• W4310030107 cites W4297502456 @default.
• W4310030107 cites W4302293777 @default.
• W4310030107 doi "https://doi.org/10.1101/2022.11.24.22282735" @default.
• W4310030107 hasPublicationYear "2022" @default.
• W4310030107 type Work @default.
• W4310030107 citedByCount "1" @default.
• W4310030107 countsByYear W43100301072023 @default.
• W4310030107 crossrefType "posted-content" @default.
• W4310030107 hasAuthorship W4310030107A5000380009 @default.
• W4310030107 hasAuthorship W4310030107A5001340042 @default.
• W4310030107 hasAuthorship W4310030107A5004143697 @default.
• W4310030107 hasAuthorship W4310030107A5006530955 @default.
• W4310030107 hasAuthorship W4310030107A5012247460 @default.
• W4310030107 hasAuthorship W4310030107A5024970229 @default.
• W4310030107 hasAuthorship W4310030107A5026081538 @default.
• W4310030107 hasAuthorship W4310030107A5026707377 @default.
• W4310030107 hasAuthorship W4310030107A5038016690 @default.
• W4310030107 hasAuthorship W4310030107A5059959150 @default.
• W4310030107 hasAuthorship W4310030107A5066359846 @default.
• W4310030107 hasAuthorship W4310030107A5067372935 @default.
• W4310030107 hasAuthorship W4310030107A5067511913 @default.
• W4310030107 hasAuthorship W4310030107A5067543646 @default.
• W4310030107 hasAuthorship W4310030107A5072307927 @default.
• W4310030107 hasAuthorship W4310030107A5078469285 @default.
• W4310030107 hasAuthorship W4310030107A5082135516 @default.
• W4310030107 hasAuthorship W4310030107A5084305363 @default.
• W4310030107 hasAuthorship W4310030107A5090299749 @default.
• W4310030107 hasBestOaLocation W43100301071 @default.
• W4310030107 hasConcept C104317684 @default.
• W4310030107 hasConcept C121332964 @default.
• W4310030107 hasConcept C12590561 @default.
• W4310030107 hasConcept C1276947 @default.
• W4310030107 hasConcept C159047783 @default.
• W4310030107 hasConcept C159654299 @default.
• W4310030107 hasConcept C203014093 @default.
• W4310030107 hasConcept C203165030 @default.
• W4310030107 hasConcept C22070199 @default.
• W4310030107 hasConcept C2779261636 @default.
• W4310030107 hasConcept C2779341262 @default.
• W4310030107 hasConcept C2780115692 @default.
• W4310030107 hasConcept C2780868878 @default.
• W4310030107 hasConcept C32611913 @default.
• W4310030107 hasConcept C54355233 @default.
• W4310030107 hasConcept C71924100 @default.
• W4310030107 hasConcept C86803240 @default.
• W4310030107 hasConcept C8891405 @default.
• W4310030107 hasConceptScore W4310030107C104317684 @default.
• W4310030107 hasConceptScore W4310030107C121332964 @default.
• W4310030107 hasConceptScore W4310030107C12590561 @default.
• W4310030107 hasConceptScore W4310030107C1276947 @default.

• next